Gene description for SEMG1
Gene name semenogelin I
Gene symbol SEMG1
Other names/aliases CT103
SEMG
SGI
dJ172H20.2
Species Homo sapiens
 Database cross references - SEMG1
ExoCarta ExoCarta_6406
Entrez Gene 6406
HGNC 10742
MIM 182140
UniProt P04279  
 SEMG1 identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for SEMG1
Molecular Function
    protein binding GO:0005515 IPI
    structural molecule activity GO:0005198 IEA
Biological Process
    negative regulation of sperm motility GO:1901318 IDA
    negative regulation of calcium ion import GO:0090281 IDA
    insemination GO:0007320 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    secretory granule GO:0030141 IEA
    nucleus GO:0005634 IDA
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 TAS
 Experiment description of studies that identified SEMG1 in exosomes
1
Experiment ID 196
ISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|TSG101|HSP70
EV Cytosolic markers
✔
CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
ISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|TSG101|HSP70
EV Cytosolic markers
✔
CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEMG1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TGM1 7051
Invitro Homo sapiens
2 SEMG2 6407
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which SEMG1 is involved
PathwayEvidenceSource
Amyloids TAS Reactome





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