Gene description for TXNDC16
Gene name thioredoxin domain containing 16
Gene symbol TXNDC16
Other names/aliases ERp90
KIAA1344
Species Homo sapiens
 Database cross references - TXNDC16
ExoCarta ExoCarta_57544
Vesiclepedia VP_57544
Entrez Gene 57544
HGNC 19965
MIM 616179
UniProt Q9P2K2  
 TXNDC16 identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for TXNDC16
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified TXNDC16 in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for TXNDC16
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LYZL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 PDGFA 5154
Affinity Capture-MS Homo sapiens
3 CCL3  
Affinity Capture-MS Homo sapiens
4 LY6H  
Affinity Capture-MS Homo sapiens
5 WFDC6  
Affinity Capture-MS Homo sapiens
6 GPIHBP1  
Affinity Capture-MS Homo sapiens
7 ITGA5 3678
Affinity Capture-MS Homo sapiens
8 CEACAM8 1088
Affinity Capture-MS Homo sapiens
9 MARCKS 4082
Affinity Capture-MS Homo sapiens
10 PRG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 ENO1 2023
Affinity Capture-MS Homo sapiens
12 FOXRED2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 SCGB1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 LRRC59 55379
Proximity Label-MS Homo sapiens
15 PDIA4 9601
Proximity Label-MS Homo sapiens
16 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SCGB1D4  
Affinity Capture-MS Homo sapiens
18 CALR3  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
19 GGH 8836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 PLAUR 5329
Affinity Capture-MS Homo sapiens
21 PDGFRA 5156
Affinity Capture-MS Homo sapiens
22 PPIB 5479
Affinity Capture-MS Homo sapiens
23 ATP5F1 515
Affinity Capture-MS Homo sapiens
24 SEMG2 6407
Affinity Capture-MS Homo sapiens
25 TNFAIP6 7130
Affinity Capture-MS Homo sapiens
26 RPL35 11224
Affinity Capture-MS Homo sapiens
27 OS9 10956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 C1QTNF7  
Affinity Capture-MS Homo sapiens
29 INSL5  
Affinity Capture-MS Homo sapiens
30 HAL 3034
Affinity Capture-MS Homo sapiens
31 SEMG1 6406
Affinity Capture-MS Homo sapiens
32 ACAP3 116983
Affinity Capture-MS Homo sapiens
33 DNASE2B  
Affinity Capture-MS Homo sapiens
34 SUSD4  
Affinity Capture-MS Homo sapiens
35 MYC  
Affinity Capture-MS Homo sapiens
36 ACOX1 51
Affinity Capture-MS Homo sapiens
37 MCM2 4171
Affinity Capture-MS Homo sapiens
38 SCGB2A2  
Affinity Capture-MS Homo sapiens
39 C1orf54  
Affinity Capture-MS Homo sapiens
40 CRTAC1  
Affinity Capture-MS Homo sapiens
41 FLNA 2316
Affinity Capture-MS Homo sapiens
42 HYOU1 10525
Affinity Capture-MS Homo sapiens
43 DHFRL1  
Affinity Capture-MS Homo sapiens
44 TAGLN2 8407
Affinity Capture-MS Homo sapiens
45 HNRNPU 3192
Affinity Capture-MS Homo sapiens
46 FAM19A2 338811
Affinity Capture-MS Homo sapiens
47 BAGE2  
Affinity Capture-MS Homo sapiens
48 POGLUT1 56983
Affinity Capture-MS Homo sapiens
49 PLD6  
Affinity Capture-MS Homo sapiens
50 SEC61B 10952
Proximity Label-MS Homo sapiens
51 EXOSC4 54512
Affinity Capture-MS Homo sapiens
52 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TXNDC16 is involved
No pathways found





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