Gene description for ACAP3
Gene name ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Gene symbol ACAP3
Other names/aliases CENTB5
Species Homo sapiens
 Database cross references - ACAP3
ExoCarta ExoCarta_116983
Entrez Gene 116983
HGNC 16754
UniProt Q96P50  
 ACAP3 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ACAP3
Molecular Function
    GTPase activator activity GO:0005096 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    positive regulation of GTPase activity GO:0043547 IEA
 Experiment description of studies that identified ACAP3 in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ACAP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF6 3692
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ACAP3 is involved
No pathways found

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