Experiment description of studies that identified SEPT5 in exosomes

1 Experiment ID 224 ISEV standards ✔ EM|AFM EV Biophysical techniques ✔ Alix|TSG101 EV Cytosolic markers ✔ CD63|CD81 EV Membrane markers ✔ GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

2 Experiment ID 217 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101 EV Cytosolic markers ✔ CD81|CD9|CD63 EV Membrane markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for SEPT5

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MYST2   Two-hybrid Homo sapiens 2 LSM8   Two-hybrid Homo sapiens 3 PFN2 5217 Two-hybrid Homo sapiens 4 STX1A 6804 Invivo Homo sapiens Invitro Homo sapiens 5 PARK2   Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens 6 SEPT8 23176 Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 7 STX4 6810 Invitro Homo sapiens 8 SEPT2 4735 Invivo Homo sapiens Invitro Homo sapiens View the network

Pathways in which SEPT5 is involved

No pathways found