Gene description for SEPT1
Gene name septin 1
Gene symbol SEPT1
Other names/aliases DIFF6
LARP
PNUTL3
SEP1
Species Homo sapiens
 Database cross references - SEPT1
ExoCarta ExoCarta_1731
Entrez Gene 1731
HGNC 2879
MIM 612897
UniProt Q8WYJ6  
 SEPT1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SEPT1
Molecular Function
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
Biological Process
    cell division GO:0051301 IEA
    cell cycle GO:0007049 IEA
Subcellular Localization
    midbody GO:0030496 IEA
    cytoplasm GO:0005737 IEA
    microtubule organizing center GO:0005815 IEA
 Experiment description of studies that identified SEPT1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEPT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEPT1 1731
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 TOLLIP 54472
Two-hybrid Homo sapiens
3 SEPT6 23157
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SEPT1 is involved
No pathways found





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