Gene description for CEACAM8
Gene name carcinoembryonic antigen-related cell adhesion molecule 8
Gene symbol CEACAM8
Other names/aliases CD66b
CD67
CGM6
NCA-95
Species Homo sapiens
 Database cross references - CEACAM8
ExoCarta ExoCarta_1088
Entrez Gene 1088
HGNC 1820
MIM 615747
UniProt P31997  
 CEACAM8 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for CEACAM8
Biological Process
    immune response GO:0006955 TAS
    leukocyte migration GO:0050900 TAS
    blood coagulation GO:0007596 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    plasma membrane GO:0005886 TAS
    integral component of plasma membrane GO:0005887 TAS
    anchored component of membrane GO:0031225 IEA
    extracellular space GO:0005615 TAS
 Experiment description of studies that identified CEACAM8 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for CEACAM8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CEACAM1 634
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CEACAM8 is involved
PathwayEvidenceSource
Cell surface interactions at the vascular wall TAS Reactome
Fibronectin matrix formation TAS Reactome





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