Gene description for GALNT12
Gene name polypeptide N-acetylgalactosaminyltransferase 12
Gene symbol GALNT12
Other names/aliases CRCS1
GalNAc-T12
Species Homo sapiens
 Database cross references - GALNT12
ExoCarta ExoCarta_79695
Vesiclepedia VP_79695
Entrez Gene 79695
HGNC 19877
MIM 610290
UniProt Q8IXK2  
 GALNT12 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for GALNT12
Molecular Function
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 IBA
    polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 TAS
    protein binding GO:0005515 IPI
    carbohydrate binding GO:0030246 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    protein O-linked glycosylation GO:0006493 IBA
    O-glycan processing GO:0016266 TAS
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    Golgi apparatus GO:0005794 IBA
 Experiment description of studies that identified GALNT12 in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for GALNT12
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TFR2 7036
Affinity Capture-MS Homo sapiens
2 NRG1 3084
Affinity Capture-MS Homo sapiens
3 GPIHBP1  
Affinity Capture-MS Homo sapiens
4 PRG2  
Affinity Capture-MS Homo sapiens
5 ELSPBP1  
Affinity Capture-MS Homo sapiens
6 RNF219  
Affinity Capture-MS Homo sapiens
7 TMEM106A  
Affinity Capture-MS Homo sapiens
8 NAAA  
Affinity Capture-MS Homo sapiens
9 CEACAM8 1088
Affinity Capture-MS Homo sapiens
10 OIT3 170392
Affinity Capture-MS Homo sapiens
11 TTYH1  
Affinity Capture-MS Homo sapiens
12 KCNA4  
Affinity Capture-MS Homo sapiens
13 CD8B 926
Affinity Capture-MS Homo sapiens
14 LAMP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 HLA-E 3133
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 TMPRSS11B 132724
Affinity Capture-MS Homo sapiens
17 TMEM25  
Affinity Capture-MS Homo sapiens
18 CHST8 64377
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 ADAM33 80332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 BTC  
Affinity Capture-MS Homo sapiens
21 ASIC4  
Affinity Capture-MS Homo sapiens
22 CFC1  
Affinity Capture-MS Homo sapiens
23 B3GNT3 10331
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 CD1B 910
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CD1A 909
Affinity Capture-MS Homo sapiens
26 ECEL1  
Affinity Capture-MS Homo sapiens
27 RICTOR 253260
Affinity Capture-MS Homo sapiens
28 EFNB1 1947
Affinity Capture-MS Homo sapiens
29 C4orf26  
Affinity Capture-MS Homo sapiens
30 PDPN  
Affinity Capture-MS Homo sapiens
31 TMEM5  
Affinity Capture-MS Homo sapiens
32 LYZL1  
Affinity Capture-MS Homo sapiens
33 MUC5AC 4586
Biochemical Activity Homo sapiens
34 PDGFRA 5156
Affinity Capture-MS Homo sapiens
35 A2M 2
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 TUBA1A 7846
Affinity Capture-MS Homo sapiens
37 FUT3 2525
Affinity Capture-MS Homo sapiens
38 HPX 3263
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 GZMH  
Affinity Capture-MS Homo sapiens
40 CLEC12B  
Affinity Capture-MS Homo sapiens
41 SAAL1 113174
Affinity Capture-MS Homo sapiens
42 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
43 TANGO6 79613
Affinity Capture-MS Homo sapiens
44 CHRNB4  
Affinity Capture-MS Homo sapiens
45 BRICD5  
Affinity Capture-MS Homo sapiens
46 SPN 6693
Affinity Capture-MS Homo sapiens
47 SDF2L1 23753
Affinity Capture-MS Homo sapiens
48 APP 351
Reconstituted Complex Homo sapiens
49 SCGB2A2  
Affinity Capture-MS Homo sapiens
50 SIRPD  
Affinity Capture-MS Homo sapiens
51 DNAJB9 4189
Affinity Capture-MS Homo sapiens
52 TCTN2  
Affinity Capture-MS Homo sapiens
53 GINM1 116254
Affinity Capture-MS Homo sapiens
54 GALNT7 51809
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CST11  
Affinity Capture-MS Homo sapiens
56 MUC1 4582
Biochemical Activity Homo sapiens
57 RAB3GAP1 22930
Affinity Capture-MS Homo sapiens
58 MPPE1 65258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 KLRC1  
Affinity Capture-MS Homo sapiens
60 IDS  
Affinity Capture-MS Homo sapiens
61 PIANP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 SERPING1 710
Affinity Capture-MS Homo sapiens
63 PTPRA 5786
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 LYPD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 DKKL1  
Affinity Capture-MS Homo sapiens
66 MGAT4C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 GAL3ST2  
Affinity Capture-MS Homo sapiens
68 PI15  
Affinity Capture-MS Homo sapiens
69 ST3GAL3  
Affinity Capture-MS Homo sapiens
70 CXCL16 58191
Affinity Capture-MS Homo sapiens
71 CHRNA1  
Affinity Capture-MS Homo sapiens
72 PNLDC1  
Affinity Capture-MS Homo sapiens
73 ASGR1 432
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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