Gene description for FUT3
Gene name fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Gene symbol FUT3
Other names/aliases CD174
FT3B
FucT-III
LE
Les
Species Homo sapiens
 Database cross references - FUT3
ExoCarta ExoCarta_2525
Entrez Gene 2525
HGNC 4014
MIM 111100
UniProt P21217  
 FUT3 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for FUT3
Molecular Function
    3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity GO:0017060 IEA
    fucosyltransferase activity GO:0008417 IDA
    alpha-(1->3)-fucosyltransferase activity GO:0046920 IDA
Biological Process
    oligosaccharide biosynthetic process GO:0009312 IDA
    protein glycosylation GO:0006486 IEA
    cell-cell recognition GO:0009988 IC
    fucosylation GO:0036065 IEA
    macromolecule glycosylation GO:0043413 IDA
Subcellular Localization
    membrane GO:0016020 IDA
    extracellular exosome GO:0070062 IDA
    Golgi cisterna membrane GO:0032580 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified FUT3 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for FUT3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FUT3 is involved
No pathways found





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