Gene description for FAM3B
Gene name family with sequence similarity 3, member B
Gene symbol FAM3B
Other names/aliases 2-21
C21orf11
C21orf76
ORF9
PANDER
PRED44
Species Homo sapiens
 Database cross references - FAM3B
ExoCarta ExoCarta_54097
Vesiclepedia VP_54097
Entrez Gene 54097
HGNC 1253
MIM 608617
UniProt P58499  
 FAM3B identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
Saliva 19199708    
 Gene ontology annotations for FAM3B
Molecular Function
    cytokine activity GO:0005125 NAS
    protein binding GO:0005515 IPI
    carbohydrate binding GO:0030246 IEA
Biological Process
    apoptotic process GO:0006915 IEA
    signal transduction GO:0007165 IEA
    insulin secretion GO:0030073 IBA
    insulin secretion GO:0030073 IDA
Subcellular Localization
    extracellular region GO:0005576 NAS
    extracellular space GO:0005615 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified FAM3B in exosomes
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
2
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for FAM3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 MTX2 10651
Affinity Capture-MS Homo sapiens
3 TM9SF4 9777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 FUT3 2525
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
5 ATP4A 495
Affinity Capture-MS Homo sapiens
6 C9orf89 84270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 ANKRD46 157567
Affinity Capture-MS Homo sapiens
8 CBWD1 55871
Affinity Capture-MS Homo sapiens
9 LRP5 4041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ITPA 3704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 GNPTAB 79158
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM3B is involved
No pathways found





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