Gene description for CBWD1
Gene name COBW domain containing 1
Gene symbol CBWD1
Other names/aliases COBP
Species Homo sapiens
 Database cross references - CBWD1
ExoCarta ExoCarta_55871
Vesiclepedia VP_55871
Entrez Gene 55871
HGNC 17134
MIM 611078
UniProt Q9BRT8  
 CBWD1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CBWD1
Molecular Function
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
    hydrolase activity GO:0016787 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    kidney development GO:0001822 IMP
Subcellular Localization
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified CBWD1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CBWD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZMYND19  
Two-hybrid Homo sapiens
2 SENP3 26168
Affinity Capture-MS Homo sapiens
3 TRMT1L 81627
Affinity Capture-MS Homo sapiens
4 KLK15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 C2orf48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 KLK5 25818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SPRYD4 283377
Affinity Capture-MS Homo sapiens
8 PTPMT1 114971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 FAM43A  
Affinity Capture-MS Homo sapiens
10 CBWD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 OIT3 170392
Affinity Capture-MS Homo sapiens
12 TRMT6 51605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 FAM3B 54097
Affinity Capture-MS Homo sapiens
14 ENDOV  
Affinity Capture-MS Homo sapiens
15 CD79A  
Affinity Capture-MS Homo sapiens
16 SF3B3 23450
Affinity Capture-MS Homo sapiens
17 SNX21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 DUSP28  
Affinity Capture-MS Homo sapiens
19 COX20  
Affinity Capture-MS Homo sapiens
20 HLA-DPB1 3115
Affinity Capture-MS Homo sapiens
21 MUC20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 SERAC1 84947
Affinity Capture-MS Homo sapiens
23 LRRC27  
Affinity Capture-MS Homo sapiens
24 GXYLT1 283464
Affinity Capture-MS Homo sapiens
25 BTLA  
Affinity Capture-MS Homo sapiens
26 PC 5091
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 PFN3  
Affinity Capture-MS Homo sapiens
28 TGFB1 7040
Affinity Capture-MS Homo sapiens
29 APBB2  
Affinity Capture-MS Homo sapiens
30 SPRTN  
Affinity Capture-MS Homo sapiens
31 RFXANK  
Affinity Capture-MS Homo sapiens
32 MRPL23 6150
Affinity Capture-MS Homo sapiens
33 FAM174A 345757
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 CLEC2B  
Affinity Capture-MS Homo sapiens
35 GCAT  
Affinity Capture-MS Homo sapiens
36 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 BAGE2  
Affinity Capture-MS Homo sapiens
38 NXPH3  
Affinity Capture-MS Homo sapiens
39 CBWD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 C2CD2 25966
Affinity Capture-MS Homo sapiens
41 DTWD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 TACSTD2 4070
Affinity Capture-MS Homo sapiens
43 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
44 UXS1 80146
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 HSPA12B 116835
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 FAM196A  
Affinity Capture-MS Homo sapiens
47 IL17RA 23765
Affinity Capture-MS Homo sapiens
48 TIMM50 92609
Affinity Capture-MS Homo sapiens
49 NPAS1  
Affinity Capture-MS Homo sapiens
50 WFDC11  
Affinity Capture-MS Homo sapiens
51 DYNC2LI1 51626
Affinity Capture-MS Homo sapiens
52 SPANXB1  
Affinity Capture-MS Homo sapiens
53 MELK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 AGAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 TSHR 7253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 SFTA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 NUBP2 10101
Affinity Capture-MS Homo sapiens
58 BEX2  
Affinity Capture-MS Homo sapiens
59 PLBD1 79887
Affinity Capture-MS Homo sapiens
60 B4GALT2  
Affinity Capture-MS Homo sapiens
61 TUBA1A 7846
Affinity Capture-MS Homo sapiens
62 RELL2  
Affinity Capture-MS Homo sapiens
63 COMTD1 118881
Affinity Capture-MS Homo sapiens
64 RCCD1  
Affinity Capture-MS Homo sapiens
65 FDXR 2232
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 SERPINC1 462
Affinity Capture-MS Homo sapiens
67 NEK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 XAGE1B  
Affinity Capture-MS Homo sapiens
69 FIGF 2277
Affinity Capture-MS Homo sapiens
70 CDHR4  
Affinity Capture-MS Homo sapiens
71 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 DHFRL1  
Affinity Capture-MS Homo sapiens
73 RPS14P3  
Affinity Capture-MS Homo sapiens
74 ADAMTS1 9510
Affinity Capture-MS Homo sapiens
75 SAMD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 TRMT2A 27037
Affinity Capture-MS Homo sapiens
77 ARL4C 10123
Affinity Capture-MS Homo sapiens
78 PDGFRA 5156
Affinity Capture-MS Homo sapiens
79 IQGAP2 10788
Affinity Capture-MS Homo sapiens
80 UBXN6 80700
Affinity Capture-MS Homo sapiens
81 CST3 1471
Affinity Capture-MS Homo sapiens
82 RTEL1 51750
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 BRINP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 VWA2 340706
Affinity Capture-MS Homo sapiens
85 CCL22 6367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 TUBB 203068
Affinity Capture-MS Homo sapiens
87 PPM1M  
Affinity Capture-MS Homo sapiens
88 MUM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 MRPS12  
Affinity Capture-MS Homo sapiens
90 ICAM1 3383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 NPRL3  
Affinity Capture-MS Homo sapiens
92 IL25  
Affinity Capture-MS Homo sapiens
93 KLK11 11012
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 ANAPC10  
Affinity Capture-MS Homo sapiens
95 B3GNT3 10331
Affinity Capture-MS Homo sapiens
96 SSX3  
Two-hybrid Homo sapiens
97 MGARP  
Affinity Capture-MS Homo sapiens
98 CUL3 8452
Affinity Capture-MS Homo sapiens
99 NPPA  
Affinity Capture-MS Homo sapiens
100 EGFR 1956
Negative Genetic Homo sapiens
101 LOC254896  
Affinity Capture-MS Homo sapiens
102 RPP30 10556
Affinity Capture-MS Homo sapiens
103 LYZL1  
Affinity Capture-MS Homo sapiens
104 DCTN3 11258
Affinity Capture-MS Homo sapiens
105 EGLN1 54583
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 MTFR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 TTF2 8458
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 PUS7 54517
Affinity Capture-MS Homo sapiens
109 RPS27 6232
Affinity Capture-MS Homo sapiens
110 C1QB 713
Affinity Capture-MS Homo sapiens
111 DDX47 51202
Affinity Capture-MS Homo sapiens
112 IL12RB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 MPZL1 9019
Affinity Capture-MS Homo sapiens
114 KLRF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 CDK20  
Affinity Capture-MS Homo sapiens
116 TRAC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 FAM167A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 CLPB 81570
Affinity Capture-MS Homo sapiens
119 OXCT2  
Affinity Capture-MS Homo sapiens
120 MRPS17 51373
Affinity Capture-MS Homo sapiens
121 CPSF3L 54973
Affinity Capture-MS Homo sapiens
122 MAPK15  
Affinity Capture-MS Homo sapiens
123 RAD51C  
Affinity Capture-MS Homo sapiens
124 HIF1A 3091
Affinity Capture-MS Homo sapiens
125 CCL3L1  
Affinity Capture-MS Homo sapiens
126 SIRT6  
Affinity Capture-MS Homo sapiens
127 PRKY  
Affinity Capture-MS Homo sapiens
128 CBWD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 FOXRED2  
Affinity Capture-MS Homo sapiens
130 NDP  
Affinity Capture-MS Homo sapiens
131 HSPA12A 259217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 TCERG1 10915
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 DNAJA2 10294
Affinity Capture-MS Homo sapiens
134 CTAG1B  
Affinity Capture-MS Homo sapiens
135 ADK 132
Affinity Capture-MS Homo sapiens
136 IQGAP3 128239
Affinity Capture-MS Homo sapiens
137 SAP18 10284
Affinity Capture-MS Homo sapiens
138 POP4 10775
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 TUBB3 10381
Affinity Capture-MS Homo sapiens
140 PPOX 5498
Affinity Capture-MS Homo sapiens
141 NDUFS7 374291
Affinity Capture-MS Homo sapiens
142 FAM83F 113828
Affinity Capture-MS Homo sapiens
143 SLAMF1 6504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 RPP38 10557
Affinity Capture-MS Homo sapiens
145 RFPL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 GZMH  
Affinity Capture-MS Homo sapiens
147 HOXB1  
Affinity Capture-MS Homo sapiens
148 TMEM25  
Affinity Capture-MS Homo sapiens
149 SIRPD  
Affinity Capture-MS Homo sapiens
150 LOC554223  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 RPL23 9349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 ERF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 RPUSD3  
Affinity Capture-MS Homo sapiens
154 WDR59 79726
Affinity Capture-MS Homo sapiens
155 EDN3  
Affinity Capture-MS Homo sapiens
156 P2RX2  
Affinity Capture-MS Homo sapiens
157 C9orf72  
Affinity Capture-MS Homo sapiens
158 GPHA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 PODN 127435
Affinity Capture-MS Homo sapiens
160 PLD6  
Affinity Capture-MS Homo sapiens
161 TUBB8 347688
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 TIMP3 7078
Affinity Capture-MS Homo sapiens
163 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 GALNT9  
Affinity Capture-MS Homo sapiens
165 ZNF146  
Affinity Capture-MS Homo sapiens
166 METAP1 23173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 PROSER2 254427
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CBWD1 is involved
No pathways found





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