Gene description for TIMM50
Gene name
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Gene symbol
TIMM50
Other names/aliases
TIM50 TIM50L
Species
Homo sapiens
Database cross references - TIMM50
ExoCarta
ExoCarta_92609
Entrez Gene
92609
HGNC
23656
MIM
607381
UniProt
Q3ZCQ8
TIMM50 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for TIMM50
Experiment description of studies that identified TIMM50 in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for TIMM50
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PAFAH1B2
5049
Two-hybrid
Homo sapiens
2
MAGED1
Affinity Capture-MS
Homo sapiens
3
TIMM23
Affinity Capture-Western
Homo sapiens
Invitro
Homo sapiens
4
TNFRSF10B
8795
Two-hybrid
Homo sapiens
5
PHB2
11331
Affinity Capture-MS
Homo sapiens
6
PELO
53918
Affinity Capture-MS
Homo sapiens
7
FTS
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which TIMM50 is involved