Gene description for ILK
Gene name	integrin-linked kinase
Gene symbol	ILK
Other names/aliases	HEL-S-28 ILK-1 ILK-2 P59 p59ILK
Species	Homo sapiens
Database cross references - ILK
ExoCarta	ExoCarta_3611
Entrez Gene	3611
HGNC	6040
MIM	602366
UniProt	Q13418
ILK identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Melanoma cells	25950383
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Prostate cancer cells	25844599
Thymus	23844026

Gene ontology annotations for ILK

Molecular Function     protein kinase binding GO:0019901 IPI     integrin binding GO:0005178 IEA     protein binding GO:0005515 IPI     protein serine/threonine kinase activity GO:0004674 IDA     SH3 domain binding GO:0017124 IEA     ATP binding GO:0005524 IEA     signal transducer activity GO:0004871 IEA Biological Process     nerve development GO:0021675 IEA     protein phosphorylation GO:0006468 IDA     negative regulation of neuron apoptotic process GO:0043524 IEA     platelet aggregation GO:0070527 IMP     positive regulation of protein kinase B signaling GO:0051897 IEA     positive regulation of cell migration GO:0030335 IEA     substrate adhesion-dependent cell spreading GO:0034446 IMP     regulation of actin cytoskeleton organization GO:0032956 IEA     cell junction assembly GO:0034329 TAS     positive regulation of axon extension GO:0045773 IEA     integrin-mediated signaling pathway GO:0007229 IDA     positive regulation of osteoblast differentiation GO:0045669 IEA     cell cycle arrest GO:0007050 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 IMP     negative regulation of smooth muscle cell migration GO:0014912 IEA     positive regulation of transcription, DNA-templated GO:0045893 IMP     branching involved in ureteric bud morphogenesis GO:0001658 IEA     cell proliferation GO:0008283 NAS     positive regulation of cell proliferation GO:0008284 IEA     positive regulation of MAP kinase activity GO:0043406 IEA     myelin assembly GO:0032288 IEA     extracellular fibril organization GO:0043206 IEA     cell aging GO:0007569 IEA     positive regulation of myoblast differentiation GO:0045663 IEA     protein kinase B signaling GO:0043491 IEA     peptidyl-serine phosphorylation GO:0018105 IEA     positive regulation of BMP signaling pathway GO:0030513 IEA     positive regulation of cell-matrix adhesion GO:0001954 IEA     negative regulation of neural precursor cell proliferation GO:2000178 IEA     establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 IEA     neuron projection morphogenesis GO:0048812 IEA     protein heterooligomerization GO:0051291 IEA     cell-matrix adhesion GO:0007160 TAS     negative regulation of protein kinase activity GO:0006469 IEA     myelination in peripheral nervous system GO:0022011 IEA     positive regulation of dendrite morphogenesis GO:0050775 IEA     negative regulation of cardiac muscle cell apoptotic process GO:0010667 IEA     fibroblast migration GO:0010761 IEA     negative regulation of smooth muscle cell proliferation GO:0048662 IEA     positive regulation of phosphorylation GO:0042327 IMP Subcellular Localization     protein complex GO:0043234 IEA     nucleoplasm GO:0005654 IDA     sarcomere GO:0030017 IEA     stress fiber GO:0001725 IEA     focal adhesion GO:0005925 IDA     cytosol GO:0005829 TAS     membrane GO:0016020 IDA     neuronal cell body GO:0043025 IEA     cell-cell junction GO:0005911 IEA     plasma membrane GO:0005886 IEA     terminal bouton GO:0043195 IEA     cell junction GO:0030054 IDA     cytoplasm GO:0005737 IDA     costamere GO:0043034 IEA     dendritic shaft GO:0043198 IEA     extracellular matrix GO:0031012 IEA     lamellipodium GO:0030027 IEA