Gene description for HAUS5
Gene name HAUS augmin-like complex, subunit 5
Gene symbol HAUS5
Other names/aliases KIAA0841
dgt5
Species Homo sapiens
 Database cross references - HAUS5
ExoCarta ExoCarta_23354
Entrez Gene 23354
HGNC 29130
MIM 613432
UniProt O94927  
 HAUS5 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Urine 19056867    
 Gene ontology annotations for HAUS5
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    centrosome organization GO:0051297 IMP
    spindle assembly GO:0051225 IMP
    cell division GO:0051301 IEA
    mitotic nuclear division GO:0007067 IEA
Subcellular Localization
    HAUS complex GO:0070652 IDA
    cytoplasm GO:0005737 IEA
    centrosome GO:0005813 IDA
    spindle GO:0005819 IEA
    microtubule GO:0005874 IEA
 Experiment description of studies that identified HAUS5 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for HAUS5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HAUS5 is involved
No pathways found





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