Gene description for ELMO3
Gene name engulfment and cell motility 3
Gene symbol ELMO3
Other names/aliases CED-12
CED12
ELMO-3
Species Homo sapiens
 Database cross references - ELMO3
ExoCarta ExoCarta_79767
Vesiclepedia VP_79767
Entrez Gene 79767
HGNC 17289
MIM 606422
UniProt Q96BJ8  
 ELMO3 identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ELMO3
Molecular Function
    protein binding GO:0005515 IPI
    SH3 domain binding GO:0017124 IEA
Biological Process
    phagocytosis GO:0006909 IEA
    apoptotic process GO:0006915 IEA
    actin filament organization GO:0007015 IBA
    cell motility GO:0048870 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ELMO3 in sEVs
1
Experiment ID 211
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ELMO3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Smchd1  
Affinity Capture-MS Mus musculus
2 SDC2 6383
Affinity Capture-MS Homo sapiens
3 Cry1  
Affinity Capture-MS Mus musculus
4 Ptpn2  
Affinity Capture-MS Mus musculus
5 LLGL2 3993
Affinity Capture-MS Homo sapiens
6 UBE2S  
Affinity Capture-MS Homo sapiens
7 DOCK4 9732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 Cyr61  
Affinity Capture-MS Mus musculus
9 FOXP2 93986
Affinity Capture-MS Homo sapiens
10 ELMO2 63916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 KIF15 56992
Affinity Capture-MS Homo sapiens
12 ELMO1 9844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 HSPA8 3312
Affinity Capture-MS Homo sapiens
14 DOCK5 80005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 UBR4 23352
Affinity Capture-MS Homo sapiens
16 TUSC2  
Affinity Capture-MS Homo sapiens
17 KCMF1 56888
Affinity Capture-MS Homo sapiens
18 SYMPK 8189
Affinity Capture-MS Homo sapiens
19 Rabep2  
Affinity Capture-MS Mus musculus
20 HAUS5 23354
Affinity Capture-MS Homo sapiens
21 METTL21B  
Affinity Capture-MS Homo sapiens
22 RBM7  
Affinity Capture-MS Homo sapiens
23 TUBA1A 7846
Affinity Capture-MS Homo sapiens
24 PCNA 5111
Affinity Capture-MS Homo sapiens
25 ARL4A  
Affinity Capture-Western Homo sapiens
26 Mis12  
Affinity Capture-MS Mus musculus
27 LOC100506753  
Protein-RNA Homo sapiens
28 DOCK1 1793
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
30 FAM174A 345757
Affinity Capture-MS Homo sapiens
31 CD244 51744
Affinity Capture-MS Homo sapiens
32 RAC2 5880
Affinity Capture-MS Homo sapiens
33 CAB39L 81617
Affinity Capture-MS Homo sapiens
34 VPS18 57617
Affinity Capture-MS Homo sapiens
35 SLC33A1 9197
Affinity Capture-MS Homo sapiens
36 DOCK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ELMO3 is involved
No pathways found





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