Gene description for KCMF1
Gene name potassium channel modulatory factor 1
Gene symbol KCMF1
Other names/aliases DEBT91
FIGC
PCMF
ZZZ1
Species Homo sapiens
 Database cross references - KCMF1
ExoCarta ExoCarta_56888
Entrez Gene 56888
HGNC 20589
MIM 614719
UniProt Q9P0J7  
 KCMF1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for KCMF1
Molecular Function
    ligase activity GO:0016874 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    metabolic process GO:0008152 IEA
 Experiment description of studies that identified KCMF1 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for KCMF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KCMF1 is involved
No pathways found





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