Gene description for UCHL5
Gene name	ubiquitin carboxyl-terminal hydrolase L5
Gene symbol	UCHL5
Other names/aliases	CGI-70 INO80R UCH-L5 UCH37
Species	Homo sapiens
Database cross references - UCHL5
ExoCarta	ExoCarta_51377
Entrez Gene	51377
HGNC	19678
MIM	610667
UniProt	Q9Y5K5
UCHL5 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Thymus	23844026

Gene ontology annotations for UCHL5

Molecular Function     ubiquitin-specific protease activity GO:0004843 IDA     omega peptidase activity GO:0008242 IEA     proteasome binding GO:0070628 IDA     poly(A) RNA binding GO:0044822 IDA     endopeptidase inhibitor activity GO:0004866 IMP     protein binding GO:0005515 IPI Biological Process     regulation of proteasomal protein catabolic process GO:0061136 IMP     negative regulation of endopeptidase activity GO:0010951 IMP     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 TAS     regulation of transcription, DNA-templated GO:0006355 IEA     lateral ventricle development GO:0021670 IEA     DNA repair GO:0006281 IEA     midbrain development GO:0030901 IEA     protein deubiquitination GO:0016579 IDA     transforming growth factor beta receptor signaling pathway GO:0007179 TAS     forebrain morphogenesis GO:0048853 IEA     ubiquitin-dependent protein catabolic process GO:0006511 IEA     DNA recombination GO:0006310 IEA     transcription, DNA-templated GO:0006351 IEA Subcellular Localization     Ino80 complex GO:0031011 IDA     cytoplasm GO:0005737 IBA     proteasome complex GO:0000502 IEA     cytosol GO:0005829 IDA     nucleus GO:0005634 IDA