Gene description for PLCG1
Gene name	phospholipase C, gamma 1
Gene symbol	PLCG1
Other names/aliases	NCKAP3 PLC-II PLC1 PLC148 PLCgamma1
Species	Homo sapiens
Database cross references - PLCG1
ExoCarta	ExoCarta_5335
Entrez Gene	5335
HGNC	9065
MIM	172420
UniProt	P19174
PLCG1 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for PLCG1

Molecular Function     calcium ion binding GO:0005509 IEA     glutamate receptor binding GO:0035254 IEA     receptor signaling protein activity GO:0005057 NAS     protein kinase binding GO:0019901 IPI     phospholipase C activity GO:0004629 TAS     receptor tyrosine kinase binding GO:0030971 IEA     neurotrophin TRKA receptor binding GO:0005168 IPI     phosphatidylinositol phospholipase C activity GO:0004435 TAS     protein binding GO:0005515 IPI Biological Process     positive regulation of epithelial cell migration GO:0010634 IMP     calcium-mediated signaling GO:0019722 IMP     Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     in utero embryonic development GO:0001701 IEA     epidermal growth factor receptor signaling pathway GO:0007173 TAS     inositol phosphate metabolic process GO:0043647 TAS     small molecule metabolic process GO:0044281 TAS     axon guidance GO:0007411 TAS     blood coagulation GO:0007596 TAS     activation of MAPKK activity GO:0000186 TAS     T cell receptor signaling pathway GO:0050852 TAS     cell migration GO:0016477 IMP     innate immune response GO:0045087 TAS     activation of phospholipase C activity GO:0007202 TAS     signal transduction GO:0007165 TAS     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     phospholipid catabolic process GO:0009395 IEA     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of blood vessel endothelial cell migration GO:0043536 IDA     cytokine-mediated signaling pathway GO:0019221 TAS     positive regulation of release of sequestered calcium ion into cytosol GO:0051281 IMP     positive regulation of angiogenesis GO:0045766 IDA     viral process GO:0016032 IEA     Fc-epsilon receptor signaling pathway GO:0038095 TAS     leukocyte migration GO:0050900 TAS     cellular response to epidermal growth factor stimulus GO:0071364 IMP Subcellular Localization     cytoplasm GO:0005737 IDA     cell-cell junction GO:0005911 IEA     plasma membrane GO:0005886 TAS     cell projection GO:0042995 IDA     cytosol GO:0005829 TAS     lamellipodium GO:0030027 IDA     ruffle GO:0001726 IDA     COP9 signalosome GO:0008180 IDA