Gene description for NTMT1
Gene name N-terminal Xaa-Pro-Lys N-methyltransferase 1
Gene symbol NTMT1
Other names/aliases AD-003
C9orf32
HOMT1A
METTL11A
NRMT
NTM1A
Species Homo sapiens
 Database cross references - NTMT1
ExoCarta ExoCarta_28989
Entrez Gene 28989
HGNC 23373
MIM 613560
UniProt Q9BV86  
 NTMT1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NTMT1
Molecular Function
    protein methyltransferase activity GO:0008276 IDA
    N-terminal protein N-methyltransferase activity GO:0071885 IBA
Biological Process
    N-terminal peptidyl-proline dimethylation GO:0018016 IDA
    chromosome segregation GO:0007059 IMP
    N-terminal peptidyl-alanine methylation GO:0018011 IBA
    N-terminal peptidyl-serine trimethylation GO:0035573 IDA
    spindle organization GO:0007051 IMP
    N-terminal peptidyl-serine dimethylation GO:0035572 IDA
    N-terminal peptidyl-alanine trimethylation GO:0018012 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified NTMT1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NTMT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NTMT1 is involved
No pathways found





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