Gene description for SNAP91
Gene name synaptosomal-associated protein, 91kDa
Gene symbol SNAP91
Other names/aliases AP180
CALM
Species Homo sapiens
 Database cross references - SNAP91
ExoCarta ExoCarta_9892
Vesiclepedia VP_9892
Entrez Gene 9892
HGNC 14986
MIM 607923
UniProt O60641  
 SNAP91 identified in exosomes derived from the following tissue/cell type
Chondrocytes 35931686    
Chondrocytes 35931686    
 Gene ontology annotations for SNAP91
Molecular Function
    protein binding GO:0005515 IPI
    clathrin binding GO:0030276 IEA
    1-phosphatidylinositol binding GO:0005545 IEA
    protein kinase binding GO:0019901 ISS
Biological Process
    clathrin coat assembly GO:0048268 IEA
    synaptic transmission GO:0007268 IEA
    regulation of clathrin-mediated endocytosis GO:2000369 IMP
    protein transport GO:0015031 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    coated pit GO:0005905 IEA
    clathrin-coated vesicle GO:0030136 IEA
 Experiment description of studies that identified SNAP91 in exosomes
1
Experiment ID 497
MISEV standards
✘ EV Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
EV Enriched markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD.
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 498
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
EV Enriched markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD.
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SNAP91
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLCG1 5335
Invivo Homo sapiens
Invitro Homo sapiens
2 EPS15 2060
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which SNAP91 is involved
No pathways found





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