Gene description for PICALM
Gene name phosphatidylinositol binding clathrin assembly protein
Gene symbol PICALM
Other names/aliases CALM
CLTH
LAP
Species Homo sapiens
 Database cross references - PICALM
ExoCarta ExoCarta_8301
Vesiclepedia VP_8301
Entrez Gene 8301
HGNC 15514
MIM 603025
UniProt Q13492  
 PICALM identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for PICALM
Molecular Function
    SNARE binding GO:0000149 IBA
    SNARE binding GO:0000149 IDA
    amyloid-beta binding GO:0001540 IC
    protein binding GO:0005515 IPI
    1-phosphatidylinositol binding GO:0005545 IBA
    1-phosphatidylinositol binding GO:0005545 ISS
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IBA
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 ISS
    clathrin binding GO:0030276 IDA
    small GTPase binding GO:0031267 IPI
    clathrin heavy chain binding GO:0032050 IBA
    clathrin heavy chain binding GO:0032050 IDA
    cadherin binding GO:0045296 HDA
    tau protein binding GO:0048156 IPI
    low-density lipoprotein particle receptor binding GO:0050750 IPI
Biological Process
    intracellular iron ion homeostasis GO:0006879 IMP
    endocytosis GO:0006897 IDA
    receptor-mediated endocytosis GO:0006898 IDA
    vesicle budding from membrane GO:0006900 IMP
    axonogenesis GO:0007409 IEA
    learning or memory GO:0007611 ISS
    negative regulation of gene expression GO:0010629 IMP
    synaptic vesicle budding from presynaptic endocytic zone membrane GO:0016185 IBA
    synaptic vesicle maturation GO:0016188 ISS
    vesicle-mediated transport GO:0016192 TAS
    endosomal transport GO:0016197 IMP
    hemopoiesis GO:0030097 IEA
    regulation of endocytosis GO:0030100 IMP
    receptor internalization GO:0031623 IMP
    regulation of protein localization GO:0032880 IDA
    vesicle cargo loading GO:0035459 IMP
    positive regulation of DNA-templated transcription GO:0045893 IDA
    positive regulation of Ras protein signal transduction GO:0046579 IMP
    negative regulation of receptor-mediated endocytosis GO:0048261 IDA
    clathrin coat assembly GO:0048268 IDA
    clathrin coat assembly GO:0048268 IMP
    dendrite morphogenesis GO:0048813 IEA
    multicellular organismal-level iron ion homeostasis GO:0060586 IMP
    protein-containing complex assembly GO:0065003 TAS
    clathrin-dependent endocytosis GO:0072583 IBA
    clathrin-dependent endocytosis GO:0072583 IMP
    regulation of vesicle size GO:0097494 IMP
    membrane bending GO:0097753 IMP
    amyloid-beta clearance by transcytosis GO:0150093 IGI
    amyloid-beta clearance by transcytosis GO:0150093 ISS
    regulation of amyloid-beta formation GO:1902003 ISS
    positive regulation of amyloid-beta formation GO:1902004 IMP
    regulation of amyloid precursor protein catabolic process GO:1902991 IMP
    positive regulation of amyloid precursor protein catabolic process GO:1902993 ISS
    negative regulation of protein localization to plasma membrane GO:1903077 IMP
    negative regulation of protein localization to cell surface GO:2000009 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    early endosome GO:0005769 IDA
    Golgi apparatus GO:0005794 IEA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    clathrin-coated pit GO:0005905 IBA
    clathrin-coated pit GO:0005905 IDA
    clathrin-coated pit GO:0005905 IMP
    synaptic vesicle GO:0008021 IBA
    cell surface GO:0009986 IDA
    membrane GO:0016020 HDA
    membrane GO:0016020 ISS
    clathrin coat of coated pit GO:0030132 IDA
    clathrin-coated vesicle GO:0030136 IBA
    clathrin-coated vesicle GO:0030136 IMP
    vesicle GO:0031982 ISS
    presynaptic membrane GO:0042734 ISS
    neuronal cell body GO:0043025 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    postsynaptic membrane GO:0045211 ISS
    clathrin-coated endocytic vesicle GO:0045334 NAS
    perinuclear region of cytoplasm GO:0048471 ISS
    endosome to plasma membrane transport vesicle GO:0070381 IDA
    neurofibrillary tangle GO:0097418 IMP
    extrinsic component of presynaptic endocytic zone membrane GO:0098894 IBA
 Experiment description of studies that identified PICALM in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PICALM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RBM38  
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 PTPRF 5792
Co-fractionation Homo sapiens
4 ITGB1 3688
Co-fractionation Homo sapiens
5 DDX3Y 8653
Affinity Capture-MS Homo sapiens
6 ISG15 9636
Affinity Capture-MS Homo sapiens
7 AP2B1 163
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 NPLOC4 55666
Co-fractionation Homo sapiens
9 MED17  
Affinity Capture-MS Homo sapiens
10 Tpm1 22003
Affinity Capture-MS Mus musculus
11 OSTC 58505
Affinity Capture-MS Homo sapiens
12 KRTCAP2 200185
Affinity Capture-MS Homo sapiens
13 MARCKS 4082
Proximity Label-MS Homo sapiens
14 LAMP3  
Proximity Label-MS Homo sapiens
15 SMURF1 57154
Biochemical Activity Homo sapiens
16 GJA1 2697
Proximity Label-MS Homo sapiens
17 POGZ 23126
Affinity Capture-MS Homo sapiens
18 Calml3  
Affinity Capture-MS Mus musculus
19 GAK 2580
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 STON2 85439
Affinity Capture-MS Homo sapiens
21 WNK1 65125
Affinity Capture-MS Homo sapiens
22 EPS15 2060
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 KIF20A 10112
Affinity Capture-MS Homo sapiens
24 NTNG1  
Affinity Capture-MS Homo sapiens
25 LAMP2 3920
Proximity Label-MS Homo sapiens
26 PTBP3 9991
Co-fractionation Homo sapiens
27 Actb 11461
Affinity Capture-MS Mus musculus
28 CLTB 1212
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SOX2  
Affinity Capture-MS Homo sapiens
30 HSPA5 3309
Affinity Capture-MS Homo sapiens
31 DNAJB6 10049
Affinity Capture-MS Homo sapiens
32 APEX1 328
Affinity Capture-RNA Homo sapiens
33 CAPZB 832
Affinity Capture-MS Homo sapiens
34 B3GAT1  
Proximity Label-MS Homo sapiens
35 TNRC6A 27327
Affinity Capture-MS Homo sapiens
36 ATP5H 10476
Cross-Linking-MS (XL-MS) Homo sapiens
37 DYRK1A 1859
Affinity Capture-MS Homo sapiens
38 MCM2 4171
Affinity Capture-MS Homo sapiens
39 AP2A1 160
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 SEC24C 9632
Co-fractionation Homo sapiens
41 SIRT1  
Affinity Capture-MS Homo sapiens
42 DDOST 1650
Affinity Capture-MS Homo sapiens
43 PLCG1 5335
Reconstituted Complex Homo sapiens
44 SERPINB1 1992
Co-fractionation Homo sapiens
45 PRRC2B  
Affinity Capture-MS Homo sapiens
46 LAMTOR3 8649
Co-fractionation Homo sapiens
47 OCLN 100506658
Proximity Label-MS Homo sapiens
48 STX6 10228
Proximity Label-MS Homo sapiens
49 ITGA4 3676
Affinity Capture-MS Homo sapiens
50 VCAM1 7412
Affinity Capture-MS Homo sapiens
51 ABCC2 1244
Co-fractionation Homo sapiens
52 GTSE1 51512
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 TRIM25 7706
Co-fractionation Homo sapiens
54 RAB35 11021
Proximity Label-MS Homo sapiens
55 ILVBL 10994
Co-fractionation Homo sapiens
56 FAM20C 56975
Affinity Capture-MS Homo sapiens
57 EEF1A1 1915
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
58 Lima1  
Affinity Capture-MS Mus musculus
59 KIF14 9928
Affinity Capture-MS Homo sapiens
60 EWSR1 2130
Co-fractionation Homo sapiens
61 ITLN1 55600
Affinity Capture-MS Homo sapiens
62 UNK  
Affinity Capture-RNA Homo sapiens
63 PFKM 5213
Co-fractionation Homo sapiens
64 YBX1 4904
Cross-Linking-MS (XL-MS) Homo sapiens
65 MYO18A 399687
Affinity Capture-MS Homo sapiens
66 ATP5A1 498
Cross-Linking-MS (XL-MS) Homo sapiens
67 ZNF444  
Affinity Capture-MS Homo sapiens
68 ATG9A 79065
Proximity Label-MS Homo sapiens
69 LPP 4026
Co-fractionation Homo sapiens
70 C9orf78 51759
Affinity Capture-MS Homo sapiens
71 ECT2 1894
Affinity Capture-MS Homo sapiens
72 PARK2  
Affinity Capture-MS Homo sapiens
73 SNAP91 9892
Affinity Capture-MS Homo sapiens
74 HOXA11  
Affinity Capture-MS Homo sapiens
75 DOT1L 84444
Cross-Linking-MS (XL-MS) Homo sapiens
76 Sec24c  
Affinity Capture-MS Mus musculus
77 MCAM 4162
Proximity Label-MS Homo sapiens
78 CLTCL1 8218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 ATG16L1 55054
Affinity Capture-MS Homo sapiens
80 DNAJC5 80331
Cross-Linking-MS (XL-MS) Homo sapiens
81 CDH1 999
Proximity Label-MS Homo sapiens
82 VCL 7414
Co-fractionation Homo sapiens
83 MYH9 4627
Affinity Capture-MS Homo sapiens
84 OGT 8473
Reconstituted Complex Homo sapiens
85 SLC25A32 81034
Affinity Capture-MS Homo sapiens
86 RDH11 51109
Affinity Capture-MS Homo sapiens
87 CENPQ  
Affinity Capture-MS Homo sapiens
88 BBS1 582
Affinity Capture-MS Homo sapiens
89 RPN1 6184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 DDX1 1653
Co-fractionation Homo sapiens
91 SNRNP27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 UNC13D 201294
Co-fractionation Homo sapiens
93 DNM2 1785
Co-fractionation Homo sapiens
94 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 DBN1 1627
Affinity Capture-MS Homo sapiens
96 DIRAS3  
Proximity Label-MS Homo sapiens
97 CARS 833
Co-fractionation Homo sapiens
98 MTSS1L 92154
Affinity Capture-MS Homo sapiens
99 ANLN 54443
Affinity Capture-MS Homo sapiens
100 HNRNPDL 9987
Co-fractionation Homo sapiens
101 LIMA1 51474
Affinity Capture-MS Homo sapiens
102 HNRNPD 3184
Co-fractionation Homo sapiens
103 NTRK1 4914
Affinity Capture-MS Homo sapiens
104 ZBTB2 57621
Affinity Capture-MS Homo sapiens
105 CLINT1 9685
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 Myh9 17886
Affinity Capture-MS Mus musculus
107 TARS 6897
Cross-Linking-MS (XL-MS) Homo sapiens
108 XPO1 7514
Affinity Capture-MS Homo sapiens
109 PIP 5304
Affinity Capture-MS Homo sapiens
110 BAG2 9532
Affinity Capture-MS Homo sapiens
111 PELI2 57161
Two-hybrid Homo sapiens
112 KLHL20  
Affinity Capture-MS Homo sapiens
113 SEC24D 9871
Co-fractionation Homo sapiens
114 STXBP1 6812
Co-fractionation Homo sapiens
115 FERMT2 10979
Co-fractionation Homo sapiens
116 C11orf49  
Affinity Capture-MS Homo sapiens
117 DOK4 55715
Affinity Capture-MS Homo sapiens
118 DAD1 1603
Affinity Capture-MS Homo sapiens
119 CYP1A1  
Affinity Capture-MS Homo sapiens
120 MYO19  
Affinity Capture-MS Homo sapiens
121 RPN2 6185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 ARF6 382
Proximity Label-MS Homo sapiens
123 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
124 FUS 2521
Co-fractionation Homo sapiens
125 HIP1R 9026
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
126 SLC25A41  
Affinity Capture-MS Homo sapiens
127 FN1 2335
Affinity Capture-MS Homo sapiens
128 AP2M1 1173
Affinity Capture-MS Homo sapiens
129 SEC13 6396
Affinity Capture-MS Homo sapiens
130 PARP1 142
Affinity Capture-MS Homo sapiens
131 MYO6 4646
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 RPA3 6119
Proximity Label-MS Homo sapiens
133 FAM64A 54478
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 EGFR 1956
Co-fractionation Homo sapiens
135 DLST 1743
Affinity Capture-MS Homo sapiens
136 STT3B 201595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 SH3GLB2 56904
Co-fractionation Homo sapiens
138 PTPN23 25930
Proximity Label-MS Homo sapiens
139 FKBP3 2287
Cross-Linking-MS (XL-MS) Homo sapiens
140 DAB2 1601
Affinity Capture-MS Homo sapiens
141 RHOB 388
Proximity Label-MS Homo sapiens
142 ILK 3611
Co-fractionation Homo sapiens
143 CLTC 1213
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
144 CD55 1604
Co-fractionation Homo sapiens
145 STAMBPL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 FSCN1 6624
Affinity Capture-MS Homo sapiens
147 RBM47 54502
Affinity Capture-MS Homo sapiens
148 BMP2K 55589
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 FLOT1 10211
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
150 OST4  
Affinity Capture-MS Homo sapiens
151 ST3GAL5  
Affinity Capture-MS Homo sapiens
152 RALBP1 10928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 RNF43  
Proximity Label-MS Homo sapiens
154 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
155 LAMTOR1 55004
Proximity Label-MS Homo sapiens
156 ITSN1 6453
Two-hybrid Homo sapiens
157 PAPOLA 10914
Co-fractionation Homo sapiens
158 ILF3 3609
Co-fractionation Homo sapiens
159 SEC16A 9919
Affinity Capture-MS Homo sapiens
160 DDX3X 1654
Affinity Capture-MS Homo sapiens
161 HIST2H2AA3 8337
Affinity Capture-MS Homo sapiens
162 Myo1c 17913
Affinity Capture-MS Mus musculus
163 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
164 CAPZA2 830
Affinity Capture-MS Homo sapiens
165 CPPED1 55313
Co-fractionation Homo sapiens
166 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
167 DENND1A 57706
Affinity Capture-MS Homo sapiens
168 C11orf52 91894
Proximity Label-MS Homo sapiens
169 MKI67  
Affinity Capture-MS Homo sapiens
170 WIF1 11197
Affinity Capture-MS Homo sapiens
171 ATP6V1F 9296
Co-fractionation Homo sapiens
172 ATF6B  
Affinity Capture-MS Homo sapiens
173 MBNL1 4154
Affinity Capture-MS Homo sapiens
174 C10orf88  
Affinity Capture-MS Homo sapiens
175 MLEC 9761
Affinity Capture-MS Homo sapiens
176 MICAL3 57553
Affinity Capture-MS Homo sapiens
177 WDR76  
Affinity Capture-MS Homo sapiens
178 ATP6V1E1 529
Co-fractionation Homo sapiens
179 PXN 5829
Co-fractionation Homo sapiens
180 PINK1  
Affinity Capture-MS Homo sapiens
181 CLTA 1211
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 CIT 11113
Affinity Capture-MS Homo sapiens
183 DNAJC6  
Affinity Capture-MS Homo sapiens
184 C14orf166 51637
Co-fractionation Homo sapiens
185 EPHA2 1969
Proximity Label-MS Homo sapiens
186 SERBP1 26135
Affinity Capture-MS Homo sapiens
187 GGA2 23062
Proximity Label-MS Homo sapiens
188 SNW1 22938
Affinity Capture-MS Homo sapiens
189 KRAS 3845
Proximity Label-MS Homo sapiens
190 POLR1D 51082
Affinity Capture-MS Homo sapiens
191 CCR1  
Affinity Capture-MS Homo sapiens
192 FCHO2 115548
Affinity Capture-MS Homo sapiens
193 CDC5L 988
Affinity Capture-MS Homo sapiens
194 CCSER2 54462
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here