Gene description for OSTC
Gene name oligosaccharyltransferase complex subunit (non-catalytic)
Gene symbol OSTC
Other names/aliases DC2
Species Homo sapiens
 Database cross references - OSTC
ExoCarta ExoCarta_58505
Entrez Gene 58505
HGNC 24448
UniProt Q9NRP0  
 OSTC identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for OSTC
Molecular Function
    protein binding GO:0005515 IPI
    dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 IC
Biological Process
    protein N-linked glycosylation via asparagine GO:0018279 IC
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    oligosaccharyltransferase complex GO:0008250 IDA
 Experiment description of studies that identified OSTC in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for OSTC
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OSTC is involved
No pathways found

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