Gene description for Tpm1
Gene name	tropomyosin 1, alpha
Gene symbol	Tpm1
Other names/aliases	AA986836 AI854628 TM2 Tm3 Tmpa Tpm-1 alpha-TM
Species	Mus musculus
Database cross references - Tpm1
ExoCarta	ExoCarta_22003
Vesiclepedia	VP_22003
Entrez Gene	22003
UniProt	P58771
Tpm1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tpm1

Molecular Function     actin binding GO:0003779 ISO     structural constituent of cytoskeleton GO:0005200 TAS     protein binding GO:0005515 IPI     cytoskeletal protein binding GO:0008092 ISO     identical protein binding GO:0042802 ISO     identical protein binding GO:0042802 ISS     protein homodimerization activity GO:0042803 ISO     protein homodimerization activity GO:0042803 ISS     protein heterodimerization activity GO:0046982 ISO     protein heterodimerization activity GO:0046982 ISS     actin filament binding GO:0051015 IBA     actin filament binding GO:0051015 IDA     actin filament binding GO:0051015 ISO     actin filament binding GO:0051015 ISS     disordered domain specific binding GO:0097718 ISO Biological Process     in utero embryonic development GO:0001701 IMP     positive regulation of heart rate by epinephrine GO:0003065 IMP     cytoskeleton organization GO:0007010 IEA     actin filament organization GO:0007015 IBA     regulation of cell shape GO:0008360 ISO     embryo development GO:0009790 IMP     muscle filament sliding GO:0030049 ISO     negative regulation of cell migration GO:0030336 ISO     ruffle organization GO:0031529 ISO     wound healing GO:0042060 ISO     sarcomere organization GO:0045214 ISO     positive regulation of cell adhesion GO:0045785 ISO     positive regulation of stress fiber assembly GO:0051496 ISO     actin filament capping GO:0051693 ISO     ventricular cardiac muscle tissue morphogenesis GO:0055010 IMP     ventricular cardiac muscle tissue morphogenesis GO:0055010 ISO     cardiac muscle contraction GO:0060048 IBA     cardiac muscle contraction GO:0060048 IMP     cardiac muscle contraction GO:0060048 ISO     negative regulation of vascular associated smooth muscle cell proliferation GO:1904706 ISO     negative regulation of vascular associated smooth muscle cell migration GO:1904753 ISO Subcellular Localization     stress fiber GO:0001725 ISO     cytoplasm GO:0005737 IDA     cytosol GO:0005829 ISO     muscle thin filament tropomyosin GO:0005862 TAS     actin filament GO:0005884 IBA     actin cytoskeleton GO:0015629 ISO     actin cytoskeleton GO:0015629 ISS     myofibril GO:0030016 IDA     bleb GO:0032059 ISO     ruffle membrane GO:0032587 ISO     protein-containing complex GO:0032991 ISO