Gene description for MYO6
Gene name myosin VI
Gene symbol MYO6
Other names/aliases DFNA22
DFNB37
Species Homo sapiens
 Database cross references - MYO6
ExoCarta ExoCarta_4646
Vesiclepedia VP_4646
Entrez Gene 4646
HGNC 7605
MIM 600970
UniProt Q9UM54  
 MYO6 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for MYO6
Molecular Function
    microfilament motor activity GO:0000146 IBA
    cytoskeletal motor activity GO:0003774 ISS
    actin binding GO:0003779 TAS
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 ISS
    calmodulin binding GO:0005516 TAS
    ATP binding GO:0005524 IEA
    identical protein binding GO:0042802 IPI
    ADP binding GO:0043531 ISS
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 IDA
    actin filament binding GO:0051015 ISS
    minus-end directed microfilament motor activity GO:0060001 NAS
Biological Process
    intracellular protein transport GO:0006886 ISS
    endocytosis GO:0006897 IBA
    endocytosis GO:0006897 IMP
    endocytosis GO:0006897 ISS
    actin filament organization GO:0007015 IBA
    sensory perception of sound GO:0007605 IEA
    protein localization GO:0008104 ISS
    response to xenobiotic stimulus GO:0009410 IEA
    actin filament-based movement GO:0030048 IBA
    actin filament-based movement GO:0030048 ISS
    actin filament-based movement GO:0030048 NAS
    DNA damage response, signal transduction by p53 class mediator GO:0030330 IDA
    inner ear morphogenesis GO:0042472 IBA
    inner ear auditory receptor cell differentiation GO:0042491 IBA
    regulation of secretion GO:0051046 IMP
Subcellular Localization
    ruffle GO:0001726 IBA
    ruffle GO:0001726 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISS
    lysosomal membrane GO:0005765 TAS
    endosome GO:0005768 IEA
    autophagosome GO:0005776 IEA
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 TAS
    actin filament GO:0005884 ISS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    microvillus GO:0005902 IEA
    clathrin-coated pit GO:0005905 IEA
    cell cortex GO:0005938 ISS
    actin cytoskeleton GO:0015629 IBA
    membrane GO:0016020 HDA
    unconventional myosin complex GO:0016461 TAS
    endocytic vesicle GO:0030139 IBA
    endocytic vesicle GO:0030139 ISS
    filopodium GO:0030175 IEA
    clathrin-coated vesicle membrane GO:0030665 IEA
    cytoplasmic vesicle GO:0031410 IDA
    filamentous actin GO:0031941 IDA
    nuclear membrane GO:0031965 IDA
    ruffle membrane GO:0032587 IEA
    apical part of cell GO:0045177 IEA
    clathrin-coated endocytic vesicle GO:0045334 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    perinuclear region of cytoplasm GO:0048471 ISS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified MYO6 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
20
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for MYO6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Proximity Label-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 KIF14 9928
Affinity Capture-MS Homo sapiens
4 AP2S1 1175
Proximity Label-MS Homo sapiens
5 ACTR2 10097
Affinity Capture-MS Homo sapiens
6 GJD3  
Proximity Label-MS Homo sapiens
7 ARL8A 127829
Affinity Capture-MS Homo sapiens
8 ISG15 9636
Affinity Capture-MS Homo sapiens
9 AP2B1 163
Affinity Capture-MS Homo sapiens
10 ZNF24  
Proximity Label-MS Homo sapiens
11 PPP1R3C  
Affinity Capture-MS Homo sapiens
12 SNRPE 6635
Affinity Capture-MS Homo sapiens
13 Tpm1 22003
Affinity Capture-MS Mus musculus
14 SEC16A 9919
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
15 BNIP2  
Proximity Label-MS Homo sapiens
16 GULP1 51454
Proximity Label-MS Homo sapiens
17 GJA1 2697
Proximity Label-MS Homo sapiens
18 SH3BP4 23677
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
19 SP1  
Affinity Capture-MS Homo sapiens
20 VPRBP 9730
Affinity Capture-MS Homo sapiens
21 CARD10  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
22 FBXO25  
Affinity Capture-MS Homo sapiens
23 APC  
Two-hybrid Homo sapiens
24 PAK2 5062
Co-fractionation Homo sapiens
25 CALM1 801
Affinity Capture-MS Homo sapiens
26 STRN3 29966
Proximity Label-MS Homo sapiens
27 KIF20A 10112
Affinity Capture-MS Homo sapiens
28 HNRNPC 3183
Proximity Label-MS Homo sapiens
29 UBC 7316
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
30 LAMP2 3920
Proximity Label-MS Homo sapiens
31 MYO5C 55930
Affinity Capture-MS Homo sapiens
32 LNPEP 4012
Proximity Label-MS Homo sapiens
33 ZFYVE16  
Proximity Label-MS Homo sapiens
34 Actb 11461
Affinity Capture-MS Mus musculus
35 CLTB 1212
Affinity Capture-MS Homo sapiens
36 SNRPF 6636
Affinity Capture-MS Homo sapiens
37 ANKRD28 23243
Proximity Label-MS Homo sapiens
38 FBXO34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 DNAJB6 10049
Proximity Label-MS Homo sapiens
40 APEX1 328
Affinity Capture-RNA Homo sapiens
41 SEPT9 10801
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
42 CAPZB 832
Affinity Capture-MS Homo sapiens
43 LAMTOR1 55004
Proximity Label-MS Homo sapiens
44 TOP2A 7153
Proximity Label-MS Homo sapiens
45 B3GAT1  
Proximity Label-MS Homo sapiens
46 PPP1CB 5500
Affinity Capture-MS Homo sapiens
47 CPSF1 29894
Proximity Label-MS Homo sapiens
48 AP2A1 160
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
49 COPB2 9276
Affinity Capture-MS Homo sapiens
50 HNRNPA1 3178
Co-fractionation Homo sapiens
51 ERC1 23085
Proximity Label-MS Homo sapiens
52 CALM3 808
Affinity Capture-MS Homo sapiens
53 HSPH1 10808
Cross-Linking-MS (XL-MS) Homo sapiens
54 PPP6R1 22870
Proximity Label-MS Homo sapiens
55 CALCOCO2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
56 KRI1  
Proximity Label-MS Homo sapiens
57 FMNL3 91010
Proximity Label-MS Homo sapiens
58 SRRM2 23524
Proximity Label-MS Homo sapiens
59 TOM1 10043
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 ABCE1 6059
Affinity Capture-MS Homo sapiens
61 EPS15L1 58513
Proximity Label-MS Homo sapiens
62 IPO8 10526
Proximity Label-MS Homo sapiens
63 CLINT1 9685
Affinity Capture-MS Homo sapiens
64 ALK 238
Affinity Capture-MS Homo sapiens
65 STX6 10228
Proximity Label-MS Homo sapiens
66 Cd2ap 12488
Affinity Capture-MS Mus musculus
67 YEATS2  
Proximity Label-MS Homo sapiens
68 PCM1 5108
Proximity Label-MS Homo sapiens
69 GTSE1 51512
Affinity Capture-MS Homo sapiens
70 PFN2 5217
Affinity Capture-MS Homo sapiens
71 NSFL1C 55968
Proximity Label-MS Homo sapiens
72 RNF126  
Affinity Capture-MS Homo sapiens
73 TFCP2 7024
Affinity Capture-MS Homo sapiens
74 FAM13A 10144
Affinity Capture-MS Homo sapiens
75 WBP2 23558
Two-hybrid Homo sapiens
76 PARP4 143
Proximity Label-MS Homo sapiens
77 ZFYVE9  
Proximity Label-MS Homo sapiens
78 MCAM 4162
Proximity Label-MS Homo sapiens
79 APPL2 55198
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 RAD23A 5886
Co-fractionation Homo sapiens
81 DOCK8 81704
Proximity Label-MS Homo sapiens
82 RNF11 26994
Two-hybrid Homo sapiens
83 GEMIN2 8487
Affinity Capture-MS Homo sapiens
84 PAK1 5058
Biochemical Activity Homo sapiens
85 RBMX 27316
Proximity Label-MS Homo sapiens
86 CALM2 805
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 SHROOM3 57619
Proximity Label-MS Homo sapiens
88 ELF3 1999
Affinity Capture-MS Homo sapiens
89 SEMA4C 54910
Proximity Label-MS Homo sapiens
90 RAD23B 5887
Co-fractionation Homo sapiens
91 MYO18A 399687
Affinity Capture-MS Homo sapiens
92 SNRNP70 6625
Affinity Capture-MS Homo sapiens
93 TRIML2  
Proximity Label-MS Homo sapiens
94 COX15 1355
Affinity Capture-MS Homo sapiens
95 ANKRD40 91369
Proximity Label-MS Homo sapiens
96 CAPZA1 829
Affinity Capture-Western Homo sapiens
97 USP11 8237
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 C9orf78 51759
Affinity Capture-MS Homo sapiens
99 PKP2 5318
Proximity Label-MS Homo sapiens
100 CUL3 8452
Affinity Capture-MS Homo sapiens
101 CEP192 55125
Proximity Label-MS Homo sapiens
102 SIPA1L1 26037
Proximity Label-MS Homo sapiens
103 OPTN 10133
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
104 LYN 4067
Proximity Label-MS Homo sapiens
105 RNF38  
Affinity Capture-MS Homo sapiens
106 TUFM 7284
Co-fractionation Homo sapiens
107 OFD1 8481
Proximity Label-MS Homo sapiens
108 DIABLO 56616
Proximity Label-MS Homo sapiens
109 ITSN2 50618
Proximity Label-MS Homo sapiens
110 DNAJC5 80331
Proximity Label-MS Homo sapiens
111 DDX20 11218
Affinity Capture-MS Homo sapiens
112 ZNF638 27332
Proximity Label-MS Homo sapiens
113 CDH1 999
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
114 YAP1 10413
Affinity Capture-MS Homo sapiens
115 MYH9 4627
Affinity Capture-MS Homo sapiens
116 VCP 7415
Proximity Label-MS Homo sapiens
117 NTRK1 4914
Affinity Capture-MS Homo sapiens
118 AKAP11 11215
Proximity Label-MS Homo sapiens
119 DPP9 91039
Co-fractionation Homo sapiens
120 ZIC3  
Affinity Capture-MS Homo sapiens
121 PHLDB2 90102
Proximity Label-MS Homo sapiens
122 DCTN1 1639
Affinity Capture-MS Homo sapiens
123 MOV10 4343
Affinity Capture-RNA Homo sapiens
124 P4HB 5034
Proximity Label-MS Homo sapiens
125 Calml3  
Affinity Capture-MS Mus musculus
126 ENO1 2023
Affinity Capture-RNA Homo sapiens
127 REPS2  
Affinity Capture-MS Homo sapiens
128 PML 5371
Affinity Capture-MS Homo sapiens
129 DBT 1629
Proximity Label-MS Homo sapiens
130 ARHGEF12 23365
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
132 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
133 FLOT2 2319
Proximity Label-MS Homo sapiens
134 PICALM 8301
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
135 GAK 2580
Affinity Capture-MS Homo sapiens
136 GTPBP4 23560
Affinity Capture-MS Homo sapiens
137 CYLD  
Affinity Capture-MS Homo sapiens
138 TOM1L2 146691
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 LRCH3 84859
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 LRCH1 23143
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 GSN 2934
Affinity Capture-MS Homo sapiens
143 GEMIN8 54960
Affinity Capture-MS Homo sapiens
144 TMPO 7112
Affinity Capture-MS Homo sapiens
145 EPS15 2060
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
146 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
147 Myh9 17886
Affinity Capture-MS Mus musculus
148 ACTBL2 345651
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 TPGS1  
Proximity Label-MS Homo sapiens
150 TRIM31  
Affinity Capture-MS Homo sapiens
151 TAX1BP1 8887
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
152 NOL8  
Proximity Label-MS Homo sapiens
153 RAB5A 5868
Proximity Label-MS Homo sapiens
154 ARRDC4  
Affinity Capture-MS Homo sapiens
155 POTEI 653269
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 DOCK7 85440
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 DNAJC2 27000
Co-fractionation Homo sapiens
158 LRCH4  
Proximity Label-MS Homo sapiens
159 RLIM 51132
Affinity Capture-MS Homo sapiens
160 CTTN 2017
Affinity Capture-MS Homo sapiens
161 AHCY 191
Proximity Label-MS Homo sapiens
162 FAM171A1 221061
Proximity Label-MS Homo sapiens
163 WDR33 55339
Proximity Label-MS Homo sapiens
164 Polrmt  
Two-hybrid Mus musculus
165 USP36  
Affinity Capture-MS Homo sapiens
166 Itga5 16402
Affinity Capture-MS Mus musculus
167 LMTK2 22853
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
168 NR3C1 2908
Proximity Label-MS Homo sapiens
169 BTF3 689
Affinity Capture-MS Homo sapiens
170 MYO19  
Affinity Capture-MS Homo sapiens
171 HOOK3 84376
Proximity Label-MS Homo sapiens
172 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
173 FBXO6 26270
Affinity Capture-MS Homo sapiens
174 FOXL1  
Proximity Label-MS Homo sapiens
175 EPRS 2058
Affinity Capture-MS Homo sapiens
176 POLR2A 5430
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
177 HSD17B10 3028
Affinity Capture-MS Homo sapiens
178 LARS 51520
Affinity Capture-MS Homo sapiens
179 MYO1C 4641
Co-fractionation Homo sapiens
180 NXF1 10482
Affinity Capture-RNA Homo sapiens
181 CDC42 998
Two-hybrid Homo sapiens
182 STRAP 11171
Affinity Capture-MS Homo sapiens
183 LZTS2 84445
Proximity Label-MS Homo sapiens
184 CDK2 1017
Affinity Capture-MS Homo sapiens
185 GEMIN4 50628
Affinity Capture-MS Homo sapiens
186 KIRREL 55243
Proximity Label-MS Homo sapiens
187 MKRN2 23609
Affinity Capture-MS Homo sapiens
188 MYL6B 140465
Affinity Capture-MS Homo sapiens
189 SYNPO 11346
Affinity Capture-MS Homo sapiens
190 NMT1 4836
Cross-Linking-MS (XL-MS) Homo sapiens
191 FOS 2353
Proximity Label-MS Homo sapiens
192 MYO6 4646
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Reconstituted Complex Homo sapiens
193 MYC  
Affinity Capture-MS Homo sapiens
194 RPA3 6119
Proximity Label-MS Homo sapiens
195 LTV1  
Proximity Label-MS Homo sapiens
196 Tmod3 50875
Affinity Capture-MS Mus musculus
197 TMOD2 29767
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 DLST 1743
Affinity Capture-MS Homo sapiens
199 RAB9A 9367
Proximity Label-MS Homo sapiens
200 AP2A2 161
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
201 TXNL1 9352
Proximity Label-MS Homo sapiens
202 CEP131 22994
Proximity Label-MS Homo sapiens
203 MAP4K4 9448
Cross-Linking-MS (XL-MS) Homo sapiens
204 DDB1 1642
Affinity Capture-MS Homo sapiens
205 SMN1 6606
Affinity Capture-MS Homo sapiens
206 AP2M1 1173
Affinity Capture-MS Homo sapiens
207 RHOB 388
Proximity Label-MS Homo sapiens
208 CLTC 1213
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
209 LRCH2  
Proximity Label-MS Homo sapiens
210 BMP2K 55589
Proximity Label-MS Homo sapiens
211 FTSJ3 117246
Proximity Label-MS Homo sapiens
212 UBXN1 51035
Affinity Capture-MS Homo sapiens
213 DAB1 1600
Reconstituted Complex Homo sapiens
214 APPL1 26060
Proximity Label-MS Homo sapiens
215 SYNRG 11276
Proximity Label-MS Homo sapiens
216 ZRANB1 54764
Affinity Capture-MS Homo sapiens
217 DZIP3  
Affinity Capture-MS Homo sapiens
218 YTHDC2 64848
Affinity Capture-MS Homo sapiens
219 RNF43  
Proximity Label-MS Homo sapiens
220 SURF6  
Proximity Label-MS Homo sapiens
221 GGA3 23163
Proximity Label-MS Homo sapiens
222 RPS27A 6233
Affinity Capture-MS Homo sapiens
223 ZDHHC5 25921
Proximity Label-MS Homo sapiens
224 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
225 GIPC1 10755
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 DAB2 1601
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Co-localization Homo sapiens
FRET Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
227 ITSN1 6453
Proximity Label-MS Homo sapiens
228 KIAA0753  
Proximity Label-MS Homo sapiens
229 WRNIP1 56897
Proximity Label-MS Homo sapiens
230 USP25  
Affinity Capture-MS Homo sapiens
231 JUP 3728
Affinity Capture-MS Homo sapiens
232 TP53 7157
Affinity Capture-MS Homo sapiens
233 G6PD 2539
Co-fractionation Homo sapiens
234 VANGL1 81839
Proximity Label-MS Homo sapiens
235 SYNJ1 8867
Proximity Label-MS Homo sapiens
236 GEMIN6  
Affinity Capture-MS Homo sapiens
237 DBN1 1627
Affinity Capture-MS Homo sapiens
238 KANK1  
Proximity Label-MS Homo sapiens
239 Myo1c 17913
Affinity Capture-MS Mus musculus
240 SIPA1L3  
Proximity Label-MS Homo sapiens
241 PDHA1 5160
Affinity Capture-MS Homo sapiens
242 LCK 3932
Proximity Label-MS Homo sapiens
243 CAPZA2 830
Affinity Capture-MS Homo sapiens
244 SQSTM1 8878
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
245 NHLRC2 374354
Co-fractionation Homo sapiens
246 DCTN2 10540
Affinity Capture-MS Homo sapiens
247 FCHO2 115548
Proximity Label-MS Homo sapiens
248 HNRNPA3 220988
Proximity Label-MS Homo sapiens
249 EPN2 22905
Proximity Label-MS Homo sapiens
250 TRA2B 6434
Proximity Label-MS Homo sapiens
251 PCGF3  
Affinity Capture-MS Homo sapiens
252 Myh10 77579
Affinity Capture-MS Mus musculus
253 FAM120C 54954
Proximity Label-MS Homo sapiens
254 ESR1  
Affinity Capture-MS Homo sapiens
255 UFL1 23376
Affinity Capture-MS Homo sapiens
256 PPP1R9A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
257 PAX7  
Affinity Capture-MS Homo sapiens
258 C10orf88  
Proximity Label-MS Homo sapiens
259 FAM160A1  
Proximity Label-MS Homo sapiens
260 CLCN7 1186
Proximity Label-MS Homo sapiens
261 FBXO30 84085
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 REPS1 85021
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 PCBP1 5093
Proximity Label-MS Homo sapiens
264 FLNA 2316
Affinity Capture-MS Homo sapiens
265 PINK1  
Affinity Capture-MS Homo sapiens
266 CIT 11113
Affinity Capture-MS Homo sapiens
267 TOLLIP 54472
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 STAT1 6772
Proximity Label-MS Homo sapiens
269 C9orf72  
Affinity Capture-MS Homo sapiens
270 AR 367
Affinity Capture-MS Homo sapiens
271 MTCL1 23255
Proximity Label-MS Homo sapiens
272 LRRC49  
Proximity Label-MS Homo sapiens
273 CFTR 1080
Affinity Capture-Western Homo sapiens
274 CUEDC1 404093
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
275 AP3D1 8943
Cross-Linking-MS (XL-MS) Homo sapiens
276 MAGI1  
Proximity Label-MS Homo sapiens
277 CAV1 857
Proximity Label-MS Homo sapiens
278 MYL12B 103910
Affinity Capture-MS Homo sapiens
279 CCSER2 54462
Proximity Label-MS Homo sapiens
280 IRF8  
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here