Gene description for MYO6
Gene name	myosin VI
Gene symbol	MYO6
Other names/aliases	DFNA22 DFNB37
Species	Homo sapiens
Database cross references - MYO6
ExoCarta	ExoCarta_4646
Entrez Gene	4646
HGNC	7605
MIM	600970
UniProt	Q9UM54
MYO6 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Neuroblastoma cells	25944692
Thymus	23844026
Urine	19056867

Gene ontology annotations for MYO6

Molecular Function     motor activity GO:0003774 ISS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     minus-end directed microfilament motor activity GO:0060001 NAS     actin filament binding GO:0051015 ISS     ADP binding GO:0043531 ISS     actin binding GO:0003779 TAS     calmodulin binding GO:0005516 TAS Biological Process     actin filament-based movement GO:0030048 NAS     regulation of synaptic plasticity GO:0048167 IEA     inner ear morphogenesis GO:0042472 IEA     synaptic transmission GO:0007268 TAS     DNA damage response, signal transduction by p53 class mediator GO:0030330 IDA     endocytosis GO:0006897 ISS     metabolic process GO:0008152 NAS     regulation of secretion GO:0051046 IMP     locomotory behavior GO:0007626 IEA     sensory perception of sound GO:0007605 IEA     glutamate secretion GO:0014047 IEA     synapse assembly GO:0007416 IEA     intracellular protein transport GO:0006886 ISS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP     protein targeting GO:0006605 IEA     membrane organization GO:0061024 TAS     auditory receptor cell differentiation GO:0042491 IEA     dendrite development GO:0016358 IEA     response to drug GO:0042493 IEA     cellular response to electrical stimulus GO:0071257 IEA Subcellular Localization     membrane GO:0016020 IDA     filamentous actin GO:0031941 ISS     nucleus GO:0005634 IDA     perinuclear region of cytoplasm GO:0048471 ISS     clathrin-coated endocytic vesicle GO:0045334 IDA     unconventional myosin complex GO:0016461 TAS     axon GO:0030424 IEA     nuclear membrane GO:0031965 IDA     coated pit GO:0005905 IEA     ruffle GO:0001726 IDA     cytoplasmic membrane-bounded vesicle GO:0016023 IDA     extracellular exosome GO:0070062 IDA     DNA-directed RNA polymerase II, holoenzyme GO:0016591 IDA     endocytic vesicle GO:0030139 ISS     cytoplasm GO:0005737 ISS     cytosol GO:0005829 TAS     apical part of cell GO:0045177 IEA     ruffle membrane GO:0032587 IEA     neuronal cell body GO:0043025 IEA     Golgi apparatus GO:0005794 IDA     cell cortex GO:0005938 ISS     clathrin-coated vesicle membrane GO:0030665 IEA     lysosomal membrane GO:0005765 TAS     nucleoplasm GO:0005654 IDA     plasma membrane GO:0005886 TAS     microvillus GO:0005902 IEA