Gene description for REPS1
Gene name RALBP1 associated Eps domain containing 1
Gene symbol REPS1
Other names/aliases RALBP1
Species Homo sapiens
 Database cross references - REPS1
ExoCarta ExoCarta_85021
Vesiclepedia VP_85021
Entrez Gene 85021
HGNC 15578
MIM 614825
UniProt Q96D71  
 REPS1 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for REPS1
Molecular Function
    calcium ion binding GO:0005509 IEA
    SH3 domain binding GO:0017124 IPI
    protein binding GO:0005515 IPI
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    coated pit GO:0005905 IDA
 Experiment description of studies that identified REPS1 in exosomes
1
Experiment ID 834
MISEV standards
EM
EV Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
EV Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for REPS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSF1  
Affinity Capture-MS Homo sapiens
2 RALB 5899
Affinity Capture-MS Homo sapiens
3 GRB2 2885
Affinity Capture-MS Homo sapiens
4 RALBP1 10928
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
5 RAB11FIP2  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which REPS1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here