Experiment description of studies that identified PNMA1 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for PNMA1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 FOXD4L3   Two-hybrid Homo sapiens 2 MCM7 4176 Two-hybrid Homo sapiens 3 SLIRP 81892 Two-hybrid Homo sapiens 4 HDAC4   Two-hybrid Homo sapiens 5 C14orf105   Two-hybrid Homo sapiens 6 POLDIP3 84271 Two-hybrid Homo sapiens 7 MED8   Two-hybrid Homo sapiens 8 POLM   Two-hybrid Homo sapiens 9 ZNF438   Two-hybrid Homo sapiens 10 SUV39H2 79723 Two-hybrid Homo sapiens 11 SCNM1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 12 GTPBP10   Two-hybrid Homo sapiens 13 PARD3 56288 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 MYO15B 80022 Two-hybrid Homo sapiens 15 SHISA3   Two-hybrid Homo sapiens 16 TRIM33 51592 Affinity Capture-MS Homo sapiens 17 MRPL10 124995 Two-hybrid Homo sapiens 18 ENKD1   Two-hybrid Homo sapiens 19 RBM41   Two-hybrid Homo sapiens 20 SLC25A48   Two-hybrid Homo sapiens 21 TTC23   Two-hybrid Homo sapiens 22 HAPLN2   Two-hybrid Homo sapiens 23 SPG7   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 24 HOXB9   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 25 BTBD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 DCTN4 51164 Two-hybrid Homo sapiens 27 MRPL23 6150 Two-hybrid Homo sapiens 28 PER1   Two-hybrid Homo sapiens 29 ZNF148   Two-hybrid Homo sapiens 30 POLL   Two-hybrid Homo sapiens 31 CHMP2B 25978 Two-hybrid Homo sapiens 32 SEMA4C 54910 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 33 UBQLN1 29979 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 34 AGTR1   Two-hybrid Homo sapiens 35 CCDC33 80125 Two-hybrid Homo sapiens 36 ATP5O 539 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 37 PNMAL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 ZNF35   Two-hybrid Homo sapiens 39 IGFN1   Two-hybrid Homo sapiens 40 ABHD17A 81926 Two-hybrid Homo sapiens 41 MARK4   Affinity Capture-MS Homo sapiens 42 PKN3 29941 Two-hybrid Homo sapiens 43 SDCBP 6386 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 44 FBF1   Two-hybrid Homo sapiens 45 UBQLN4 56893 Two-hybrid Homo sapiens 46 NIF3L1 60491 Two-hybrid Homo sapiens 47 FAS 355 Proximity Label-MS Homo sapiens 48 KANSL1   Two-hybrid Homo sapiens 49 TRIM73   Two-hybrid Homo sapiens 50 ATP6V1G1 9550 Two-hybrid Homo sapiens 51 ACTA2 59 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 FMNL2 114793 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 53 GPR25   Two-hybrid Homo sapiens 54 BEX2   Two-hybrid Homo sapiens 55 FAM161B   Two-hybrid Homo sapiens 56 HCK 3055 Two-hybrid Homo sapiens 57 CCAR2 57805 Affinity Capture-MS Homo sapiens 58 FAM110A   Two-hybrid Homo sapiens 59 BTBD2   Affinity Capture-MS Homo sapiens 60 TCEA2   Two-hybrid Homo sapiens 61 TRIM42   Two-hybrid Homo sapiens 62 SCAND1   Two-hybrid Homo sapiens 63 PNMA5 114824 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 64 FOXD4L1   Two-hybrid Homo sapiens 65 CNNM3 26505 Two-hybrid Homo sapiens 66 FAM107A   Two-hybrid Homo sapiens 67 RSRC2   Two-hybrid Homo sapiens 68 NSMF   Two-hybrid Homo sapiens 69 GEM   Two-hybrid Homo sapiens 70 C5orf30   Two-hybrid Homo sapiens 71 MOAP1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 RAPGEF3 10411 Two-hybrid Homo sapiens 73 TSPYL4 23270 Two-hybrid Homo sapiens 74 PNMA2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 PKN1 5585 Two-hybrid Homo sapiens 76 TTC9C 283237 Two-hybrid Homo sapiens 77 ACTB 60 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 78 ARHGEF6 9459 Two-hybrid Homo sapiens 79 PRPF18   Two-hybrid Homo sapiens 80 ZNF581   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 81 HECTD1 25831 Affinity Capture-MS Homo sapiens 82 VAV2 7410 Two-hybrid Homo sapiens 83 MRPL11 65003 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 84 ACOX1 51 Affinity Capture-MS Homo sapiens 85 PRPF31 26121 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 86 PNMA6A   Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 87 TEAD4   Two-hybrid Homo sapiens 88 DAXX   Two-hybrid Homo sapiens 89 WDYHV1   Two-hybrid Homo sapiens 90 SNRPB2 6629 Two-hybrid Homo sapiens 91 TRPV6   Two-hybrid Homo sapiens 92 RAD51D   Two-hybrid Homo sapiens 93 RUSC1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 94 COX5B 1329 Two-hybrid Homo sapiens 95 MAP7 9053 Affinity Capture-MS Homo sapiens 96 MYOZ1   Two-hybrid Homo sapiens 97 ARID5A   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 98 BYSL 705 Two-hybrid Homo sapiens 99 SPATC1L   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 100 SNRPB 6628 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 101 ZNF564   Two-hybrid Homo sapiens 102 WDR25   Two-hybrid Homo sapiens 103 ACTBL2 345651 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 YWHAZ 7534 Affinity Capture-MS Homo sapiens 105 USP2   Two-hybrid Homo sapiens 106 MAB21L2   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 107 GADD45GIP1   Two-hybrid Homo sapiens 108 SMIM3   Two-hybrid Homo sapiens 109 NPBWR2   Two-hybrid Homo sapiens 110 TXNDC9 10190 Two-hybrid Homo sapiens 111 WT1-AS   Two-hybrid Homo sapiens 112 PRKCI 5584 Affinity Capture-MS Homo sapiens 113 GPANK1   Two-hybrid Homo sapiens 114 RPP25   Two-hybrid Homo sapiens 115 INO80B 83444 Two-hybrid Homo sapiens 116 FAM208B 54906 Two-hybrid Homo sapiens 117 MGC50722   Two-hybrid Homo sapiens 118 NUDT16L1 84309 Two-hybrid Homo sapiens 119 CCNG1   Two-hybrid Homo sapiens 120 CARHSP1 23589 Two-hybrid Homo sapiens 121 SHC3   Two-hybrid Homo sapiens 122 TCEANC   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 123 STAMBPL1   Two-hybrid Homo sapiens 124 ZC2HC1C   Two-hybrid Homo sapiens 125 ZCCHC12   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 PIN4 5303 Two-hybrid Homo sapiens 127 CFAP53   Two-hybrid Homo sapiens 128 ANKRD36BP1   Two-hybrid Homo sapiens 129 C8orf33 65265 Two-hybrid Homo sapiens 130 VBP1 7411 Two-hybrid Homo sapiens 131 CTNNA3   Two-hybrid Homo sapiens 132 RTP5   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 133 APTX   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 134 UBA5 79876 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 135 C21orf58   Two-hybrid Homo sapiens 136 RPP25L   Two-hybrid Homo sapiens 137 RSPH9   Two-hybrid Homo sapiens 138 CCDC146   Two-hybrid Homo sapiens 139 PIN1 5300 Two-hybrid Homo sapiens 140 KAT2B   Two-hybrid Homo sapiens 141 ATXN7   Two-hybrid Homo sapiens 142 FEM1C   Two-hybrid Homo sapiens 143 CDK18 5129 Two-hybrid Homo sapiens 144 TSHZ2   Two-hybrid Homo sapiens 145 ZG16B 124220 Two-hybrid Homo sapiens 146 PSMA1 5682 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 147 URB1-AS1   Two-hybrid Homo sapiens 148 ASMTL 8623 Two-hybrid Homo sapiens 149 CHIC2 26511 Two-hybrid Homo sapiens 150 TCL1B   Two-hybrid Homo sapiens 151 LAGE3   Two-hybrid Homo sapiens 152 REPS1 85021 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 153 FAM161A   Two-hybrid Homo sapiens 154 PCGF6   Two-hybrid Homo sapiens 155 CBX8 57332 Two-hybrid Homo sapiens 156 C1orf109   Two-hybrid Homo sapiens 157 FBXL18 80028 Two-hybrid Homo sapiens 158 EHHADH 1962 Two-hybrid Homo sapiens 159 TMSB4X 7114 Two-hybrid Homo sapiens 160 SH2D4A 63898 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 161 METTL17   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 162 ZFYVE26 23503 Two-hybrid Homo sapiens 163 ZNF318 24149 Affinity Capture-MS Homo sapiens 164 LIN37   Two-hybrid Homo sapiens 165 TNNI1 7135 Two-hybrid Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which PNMA1 is involved

No pathways found