Gene description for MAP7
Gene name microtubule-associated protein 7
Gene symbol MAP7
Other names/aliases E-MAP-115
EMAP115
Species Homo sapiens
 Database cross references - MAP7
ExoCarta ExoCarta_9053
Entrez Gene 9053
HGNC 6869
MIM 604108
UniProt Q14244  
 MAP7 identified in exosomes derived from the following tissue/cell type
Mesothelioma cells 15111327    
 Gene ontology annotations for MAP7
Molecular Function
    receptor binding GO:0005102 ISS
    structural molecule activity GO:0005198 TAS
Biological Process
    establishment or maintenance of cell polarity GO:0007163 TAS
    protein localization to plasma membrane GO:0072659 ISS
    response to osmotic stress GO:0006970 ISS
    microtubule cytoskeleton organization GO:0000226 IEA
Subcellular Localization
    basolateral plasma membrane GO:0016323 IEA
    microtubule GO:0005874 IEA
    perinuclear region of cytoplasm GO:0048471 IEA
    microtubule cytoskeleton GO:0015630 IDA
    microtubule associated complex GO:0005875 TAS
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified MAP7 in exosomes
1
Experiment ID 25
ISEV standards
IEM
EV Biophysical techniques
HSP90|beta-tubulin
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15111327    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes secreted by human mesothelioma cells.
Authors Hegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN.
Journal name AJP
Publication year 2004
Sample Mesothelioma cells
Sample name PMR-MM7
PMR-MM8
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for MAP7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRPV4 59341
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which MAP7 is involved
No pathways found





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