Gene description for TUBB4B
Gene name tubulin, beta 4B class IVb
Gene symbol TUBB4B
Other names/aliases Beta2
TUBB2
TUBB2C
Species Homo sapiens
 Database cross references - TUBB4B
ExoCarta ExoCarta_10383
Vesiclepedia VP_10383
Entrez Gene 10383
HGNC 20771
MIM 602660
UniProt P68371  
 TUBB4B identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Intestinal epithelial cells 11487543    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for TUBB4B
Molecular Function
    double-stranded RNA binding GO:0003725 IDA
    GTPase activity GO:0003924 IEA
    structural constituent of cytoskeleton GO:0005200 IBA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    MHC class I protein binding GO:0042288 TAS
    metal ion binding GO:0046872 IEA
    unfolded protein binding GO:0051082 NAS
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    mitotic cell cycle GO:0000278 IBA
    flagellated sperm motility GO:0030317 IEA
    natural killer cell mediated cytotoxicity GO:0042267 NAS
Subcellular Localization
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 HDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 TAS
    microtubule GO:0005874 IBA
    microtubule GO:0005874 IDA
    axonemal microtubule GO:0005879 IDA
    microtubule cytoskeleton GO:0015630 IDA
    azurophil granule lumen GO:0035578 TAS
    sperm flagellum GO:0036126 IEA
    intercellular bridge GO:0045171 IDA
    extracellular exosome GO:0070062 HDA
    mitotic spindle GO:0072686 IDA
    extracellular vesicle GO:1903561 HDA
 Experiment description of studies that identified TUBB4B in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 1221
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 1222
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213D5
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
20
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
21
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
22
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
30
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 4
MISEV standards
✔
IEM
Biophysical techniques
✔
CD63|MHCI|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 11487543    
Organism Homo sapiens
Experiment description Intestinal epithelial cells secrete exosome-like vesicles.
Authors "van Niel G, Raposo G, Candalh C, Boussac M, Hershberg R, Cerf-Bensussan N, Heyman M"
Journal name Not applicable
Publication year 2001
Sample Intestinal epithelial cells
Sample name HT29-19A
T84-DRB1*0401/CIITA
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
35
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
38
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
40
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
54
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
55
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
56
Experiment ID 146
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name RWPE - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
57
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
58
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
59
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
60
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
61
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
62
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TUBB4B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBL4A 8266
Affinity Capture-MS Homo sapiens
2 SHC1 6464
Affinity Capture-MS Homo sapiens
3 RIN3  
Affinity Capture-MS Homo sapiens
4 DYNC1I2 1781
Affinity Capture-MS Homo sapiens
5 CRK 1398
Affinity Capture-MS Homo sapiens
6 TUBB8 347688
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SETX  
Affinity Capture-MS Homo sapiens
8 VHL  
Affinity Capture-MS Homo sapiens
9 MID1 4281
Affinity Capture-MS Homo sapiens
10 SCG2  
Two-hybrid Homo sapiens
11 TACC2 10579
Affinity Capture-MS Homo sapiens
12 HMMR  
Affinity Capture-MS Homo sapiens
13 EFNA3  
Affinity Capture-MS Homo sapiens
14 WDR62  
Affinity Capture-MS Homo sapiens
15 WDR76  
Affinity Capture-MS Homo sapiens
16 ZBTB21  
Affinity Capture-MS Homo sapiens
17 GNS 2799
Co-fractionation Homo sapiens
18 GLMP 112770
Affinity Capture-MS Homo sapiens
19 PFDN4 5203
Affinity Capture-MS Homo sapiens
20 POU5F1  
Affinity Capture-MS Homo sapiens
21 PPEF1  
Affinity Capture-MS Homo sapiens
22 MAGED2 10916
Affinity Capture-MS Homo sapiens
23 HERC2 8924
Affinity Capture-MS Homo sapiens
24 ARIH2 10425
Affinity Capture-MS Homo sapiens
25 PFDN6 10471
Affinity Capture-MS Homo sapiens
26 DYNLT1 6993
Affinity Capture-MS Homo sapiens
27 KIF14 9928
Affinity Capture-MS Homo sapiens
28 CLASP2 23122
Affinity Capture-MS Homo sapiens
29 BAG5 9529
Affinity Capture-MS Homo sapiens
30 AURKA 6790
Affinity Capture-MS Homo sapiens
31 DNAL4  
Affinity Capture-MS Homo sapiens
32 USP11 8237
Affinity Capture-MS Homo sapiens
33 MAP1B 4131
Co-fractionation Homo sapiens
34 PSME1 5720
Two-hybrid Homo sapiens
35 CDH1 999
Proximity Label-MS Homo sapiens
36 YAP1 10413
Affinity Capture-MS Homo sapiens
37 MYH9 4627
Co-fractionation Homo sapiens
38 TRIM21 6737
Affinity Capture-MS Homo sapiens
39 SLX4  
Affinity Capture-MS Homo sapiens
40 PEX14 5195
Co-purification Homo sapiens
41 BICD2 23299
Affinity Capture-MS Homo sapiens
42 YWHAQ 10971
Affinity Capture-MS Homo sapiens
43 HECTD1 25831
Affinity Capture-MS Homo sapiens
44 CUL2 8453
Affinity Capture-MS Homo sapiens
45 TRMT2A 27037
Affinity Capture-MS Homo sapiens
46 KCNH5  
Affinity Capture-MS Homo sapiens
47 CCNT1  
Co-fractionation Homo sapiens
48 ID2  
Affinity Capture-MS Homo sapiens
49 MGMT 4255
Affinity Capture-MS Homo sapiens
50 ACD  
Two-hybrid Homo sapiens
51 PHLPP1  
Proximity Label-MS Homo sapiens
52 HADHA 3030
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
53 AHCYL1 10768
Co-fractionation Homo sapiens
54 ZNF622 90441
Affinity Capture-MS Homo sapiens
55 IQCB1  
Affinity Capture-MS Homo sapiens
56 MADD 8567
Affinity Capture-MS Homo sapiens
57 FN1 2335
Affinity Capture-MS Homo sapiens
58 TXNDC9 10190
Affinity Capture-MS Homo sapiens
59 TUBA4A 7277
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
60 PCBP1 5093
Affinity Capture-MS Homo sapiens
61 RPA3 6119
Affinity Capture-MS Homo sapiens
62 DLST 1743
Two-hybrid Homo sapiens
63 CDC20 991
Affinity Capture-MS Homo sapiens
64 TCP11L2  
Affinity Capture-MS Homo sapiens
65 STMN1 3925
Affinity Capture-MS Homo sapiens
66 TBCA 6902
Affinity Capture-MS Homo sapiens
67 CTNNA1 1495
Affinity Capture-MS Homo sapiens
68 PAFAH1B1 5048
Affinity Capture-MS Homo sapiens
69 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
70 Tubg1 103733
Affinity Capture-MS Mus musculus
71 CCT7 10574
Affinity Capture-MS Homo sapiens
72 GRB2 2885
Affinity Capture-MS Homo sapiens
73 ZEB1  
Affinity Capture-MS Homo sapiens
74 CENPJ 55835
Affinity Capture-MS Homo sapiens
75 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
76 PFDN1 5201
Affinity Capture-MS Homo sapiens
77 ZC2HC1A 51101
Affinity Capture-MS Homo sapiens
78 DCTN2 10540
Affinity Capture-MS Homo sapiens
79 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 RPS15A 6210
Co-fractionation Homo sapiens
81 SSBP1 6742
Affinity Capture-MS Homo sapiens
82 PSMA1 5682
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
83 Tuba3a 22144
Affinity Capture-MS Mus musculus
84 GPR50  
Affinity Capture-MS Homo sapiens
85 CNTRL  
Affinity Capture-MS Homo sapiens
86 CLASP1 23332
Affinity Capture-MS Homo sapiens
87 CAPS 828
Affinity Capture-MS Homo sapiens
88 CYLD  
Affinity Capture-MS Homo sapiens
89 STMN3  
Affinity Capture-MS Homo sapiens
90 TXNIP 10628
Affinity Capture-MS Homo sapiens
91 SNW1 22938
Affinity Capture-MS Homo sapiens
92 CLIP4  
Affinity Capture-MS Homo sapiens
93 CEP170 9859
Affinity Capture-MS Homo sapiens
94 RANGAP1 5905
Affinity Capture-MS Homo sapiens
95 TRAF1 7185
Affinity Capture-MS Homo sapiens
96 PTPRF 5792
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
97 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 CLIP1 6249
Affinity Capture-MS Homo sapiens
99 EML2 24139
Affinity Capture-MS Homo sapiens
100 RPA2 6118
Affinity Capture-MS Homo sapiens
101 ENOX2  
Two-hybrid Homo sapiens
102 APC  
Affinity Capture-MS Homo sapiens
103 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
104 FDXR 2232
Affinity Capture-MS Homo sapiens
105 LOC260334  
Affinity Capture-MS Homo sapiens
106 CAND1 55832
Affinity Capture-MS Homo sapiens
107 AFTPH  
Affinity Capture-MS Homo sapiens
108 MFAP5  
Affinity Capture-MS Homo sapiens
109 DNAJB6 10049
Affinity Capture-MS Homo sapiens
110 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
111 LRP1 4035
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 PIGN 23556
Affinity Capture-MS Homo sapiens
113 B3GNT2 10678
Affinity Capture-MS Homo sapiens
114 JAKMIP1 152789
Affinity Capture-MS Homo sapiens
115 PSMA3 5684
Affinity Capture-MS Homo sapiens
116 COPS6 10980
Affinity Capture-MS Homo sapiens
117 FAM83D 81610
Affinity Capture-MS Homo sapiens
118 PRC1 9055
Affinity Capture-MS Homo sapiens
119 ACTR1A 10121
Affinity Capture-MS Homo sapiens
120 RECQL4  
Affinity Capture-MS Homo sapiens
121 OBSL1 23363
Affinity Capture-MS Homo sapiens
122 TINF2  
Two-hybrid Homo sapiens
123 STIP1 10963
Affinity Capture-MS Homo sapiens
124 TUBA3C 7278
Co-fractionation Homo sapiens
125 VCAM1 7412
Affinity Capture-MS Homo sapiens
126 TUBB6 84617
Co-fractionation Homo sapiens
127 CUL1 8454
Affinity Capture-MS Homo sapiens
128 ZNHIT6 54680
Affinity Capture-MS Homo sapiens
129 DLGAP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
131 YWHAB 7529
Co-fractionation Homo sapiens
132 CCT2 10576
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 VRK3 51231
Affinity Capture-MS Homo sapiens
134 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
135 TBCE 6905
Affinity Capture-MS Homo sapiens
136 PSMD14 10213
Affinity Capture-MS Homo sapiens
137 CBL 867
Affinity Capture-MS Homo sapiens
138 CAPSL  
Affinity Capture-MS Homo sapiens
139 SNRNP200 23020
Co-fractionation Homo sapiens
140 TUBB2B 347733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 TUBA1C 84790
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 RLIM 51132
Affinity Capture-MS Homo sapiens
143 ACTR10 55860
Affinity Capture-MS Homo sapiens
144 Ksr1  
Affinity Capture-MS Mus musculus
145 RAD21 5885
Affinity Capture-Western Homo sapiens
146 FBXL4 26235
Affinity Capture-MS Homo sapiens
147 TUBB 203068
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
148 MAP7 9053
Affinity Capture-MS Homo sapiens
149 AIFM1 9131
Affinity Capture-MS Homo sapiens
150 XPO1 7514
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
151 TPR 7175
Co-fractionation Homo sapiens
152 IKZF3  
Affinity Capture-MS Homo sapiens
153 PRKAR2A 5576
Affinity Capture-MS Homo sapiens
154 CDC42EP1 11135
Affinity Capture-MS Homo sapiens
155 PRCP 5547
Co-fractionation Homo sapiens
156 TCP11L1 55346
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 EGFR 1956
Affinity Capture-MS Homo sapiens
158 HOOK3 84376
Affinity Capture-MS Homo sapiens
159 IKZF1  
Affinity Capture-MS Homo sapiens
160 RIPK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 EML3 256364
Affinity Capture-MS Homo sapiens
162 CDK2 1017
Affinity Capture-MS Homo sapiens
163 CEP250 11190
Affinity Capture-MS Homo sapiens
164 ZMYM6  
Affinity Capture-MS Homo sapiens
165 MYC  
Affinity Capture-MS Homo sapiens
166 IL12RB1  
Affinity Capture-MS Homo sapiens
167 CUL7 9820
Affinity Capture-MS Homo sapiens
168 DDRGK1 65992
Affinity Capture-MS Homo sapiens
169 Yap1  
Reconstituted Complex Mus musculus
170 ISOC1 51015
Co-fractionation Homo sapiens
171 PCM1 5108
Affinity Capture-MS Homo sapiens
172 PFDN5 5204
Affinity Capture-MS Homo sapiens
173 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 TACC3  
Affinity Capture-MS Homo sapiens
175 TAF6 6878
Co-fractionation Homo sapiens
176 EIF3F 8665
Affinity Capture-MS Homo sapiens
177 KIF21B 23046
Affinity Capture-MS Homo sapiens
178 SPOP  
Affinity Capture-MS Homo sapiens
179 TTC5  
Affinity Capture-MS Homo sapiens
180 TP53 7157
Affinity Capture-MS Homo sapiens
181 FOLR1 2348
Affinity Capture-MS Homo sapiens
182 MELK  
Affinity Capture-MS Homo sapiens
183 PLD6  
Affinity Capture-MS Homo sapiens
184 CLIP2 7461
Affinity Capture-MS Homo sapiens
185 GNL1 2794
Co-fractionation Homo sapiens
186 PLD3 23646
Affinity Capture-MS Homo sapiens
187 SPAG5 10615
Affinity Capture-MS Homo sapiens
188 C16orf72 29035
Affinity Capture-MS Homo sapiens
189 DYNLRB1 83658
Affinity Capture-MS Homo sapiens
190 PRMT1 3276
Affinity Capture-MS Homo sapiens
191 DYNC1LI1 51143
Affinity Capture-MS Homo sapiens
192 RANBP2 5903
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 TCP1 6950
Affinity Capture-MS Homo sapiens
194 ATP6V1B2 526
Co-fractionation Homo sapiens
195 HNRNPC 3183
Co-fractionation Homo sapiens
196 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
197 RAB1A 5861
Co-fractionation Homo sapiens
198 ALMS1  
Affinity Capture-MS Homo sapiens
199 PFKP 5214
Co-fractionation Homo sapiens
200 YWHAE 7531
Affinity Capture-MS Homo sapiens
201 RPS19 6223
Co-fractionation Homo sapiens
202 CAMSAP2  
Affinity Capture-MS Homo sapiens
203 RPS6KB2  
Affinity Capture-MS Homo sapiens
204 CEP97 79598
Affinity Capture-MS Homo sapiens
205 CAPZB 832
Affinity Capture-MS Homo sapiens
206 RPL10A 4736
Co-fractionation Homo sapiens
207 RUVBL1 8607
Co-fractionation Homo sapiens
208 TPSB2  
Affinity Capture-MS Homo sapiens
209 DYNC1LI2 1783
Affinity Capture-MS Homo sapiens
210 MCM2 4171
Affinity Capture-MS Homo sapiens
211 CAMSAP1 157922
Affinity Capture-MS Homo sapiens
212 COPB2 9276
Co-fractionation Homo sapiens
213 MCTS1 28985
Co-fractionation Homo sapiens
214 BAGE2  
Affinity Capture-MS Homo sapiens
215 PLD2 5338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 MID2 11043
Affinity Capture-MS Homo sapiens
217 ITGA4 3676
Affinity Capture-MS Homo sapiens
218 CKAP5 9793
Affinity Capture-MS Homo sapiens
219 RC3H2  
Affinity Capture-MS Homo sapiens
220 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
221 TFCP2 7024
Affinity Capture-MS Homo sapiens
222 CEP131 22994
Affinity Capture-MS Homo sapiens
223 GPRIN1 114787
Affinity Capture-MS Homo sapiens
224 HSPA8 3312
Affinity Capture-MS Homo sapiens
225 FAS 355
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 KLK5 25818
Affinity Capture-MS Homo sapiens
227 BSG 682
Affinity Capture-MS Homo sapiens
228 FOXC1  
Affinity Capture-MS Homo sapiens
229 EML4 27436
Affinity Capture-MS Homo sapiens
230 SOCS6  
Affinity Capture-MS Homo sapiens
231 CUL4B 8450
Affinity Capture-MS Homo sapiens
232 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
233 B4GALT2  
Affinity Capture-MS Homo sapiens
234 TUBA1A 7846
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
235 ASNA1 439
Co-fractionation Homo sapiens
236 PDCD5 9141
Affinity Capture-MS Homo sapiens
237 SLAIN1 122060
Affinity Capture-MS Homo sapiens
238 TNPO2 30000
Co-fractionation Homo sapiens
239 BTF3 689
Affinity Capture-MS Homo sapiens
240 NTRK1 4914
Affinity Capture-MS Homo sapiens
241 U2AF2 11338
Co-fractionation Homo sapiens
242 DNAJA1 3301
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
243 TACC1 6867
Affinity Capture-MS Homo sapiens
244 KPNB1 3837
Affinity Capture-MS Homo sapiens
245 TUBA1B 10376
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 Dlgap4  
Affinity Capture-MS Mus musculus
247 HDAC5 10014
Affinity Capture-MS Homo sapiens
248 Nek9  
Affinity Capture-MS Mus musculus
249 POLR2B 5431
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
250 TTL 150465
Affinity Capture-MS Homo sapiens
251 OGT 8473
Reconstituted Complex Homo sapiens
252 MYCBP2 23077
Affinity Capture-MS Homo sapiens
253 METTL14  
Affinity Capture-MS Homo sapiens
254 SMARCA5 8467
Co-fractionation Homo sapiens
255 DIRAS2 54769
Affinity Capture-MS Homo sapiens
256 MGARP  
Affinity Capture-MS Homo sapiens
257 NR3C1 2908
Affinity Capture-MS Homo sapiens
258 ACE2 59272
Affinity Capture-MS Homo sapiens
259 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
260 ARL2 402
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 VBP1 7411
Affinity Capture-MS Homo sapiens
262 AP2M1 1173
Affinity Capture-MS Homo sapiens
263 CEP170B  
Affinity Capture-MS Homo sapiens
264 NLRP1  
Affinity Capture-MS Homo sapiens
265 JUNB  
Co-fractionation Homo sapiens
266 RNF2  
Affinity Capture-MS Homo sapiens
267 KIAA0368 23392
Affinity Capture-MS Homo sapiens
268 HSPD1 3329
Co-fractionation Homo sapiens
269 NEUROG3  
Affinity Capture-MS Homo sapiens
270 MPHOSPH9  
Affinity Capture-MS Homo sapiens
271 TUBB2A 7280
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
272 KIF2A 3796
Affinity Capture-MS Homo sapiens
273 PHB2 11331
Co-fractionation Homo sapiens
274 CCT8 10694
Affinity Capture-MS Homo sapiens
275 CDC42SE2 56990
Affinity Capture-MS Homo sapiens
276 TUBA4B 80086
Co-fractionation Homo sapiens
277 MCM5 4174
Affinity Capture-MS Homo sapiens
278 EPHA4 2043
Affinity Capture-MS Homo sapiens
279 RPA1 6117
Affinity Capture-MS Homo sapiens
280 NME2P1 283458
Affinity Capture-MS Homo sapiens
281 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 AICDA  
Affinity Capture-Western Homo sapiens
283 PGAM2 5224
Affinity Capture-MS Homo sapiens
284 ZC2HC1B  
Affinity Capture-MS Homo sapiens
285 UFL1 23376
Affinity Capture-MS Homo sapiens
286 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 HDAC6 10013
Affinity Capture-MS Homo sapiens
288 RPL8 6132
Co-fractionation Homo sapiens
289 METTL3  
Affinity Capture-MS Homo sapiens
290 SERBP1 26135
Affinity Capture-MS Homo sapiens
291 ATXN3 4287
Affinity Capture-MS Homo sapiens
292 KIF4A 24137
Affinity Capture-MS Homo sapiens
293 CDKN2A 1029
Reconstituted Complex Homo sapiens
294 UBE2H 7328
Affinity Capture-MS Homo sapiens
295 INSIG1  
Affinity Capture-MS Homo sapiens
296 SLFN11 91607
Affinity Capture-MS Homo sapiens
297 CCT3 7203
Affinity Capture-MS Homo sapiens
298 POT1  
Two-hybrid Homo sapiens
299 SSR2  
Affinity Capture-MS Homo sapiens
300 SMURF1 57154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 NCALD 83988
Affinity Capture-MS Homo sapiens
302 FBXO25  
Affinity Capture-MS Homo sapiens
303 WNT7A  
Affinity Capture-MS Homo sapiens
304 CCT4 10575
Affinity Capture-MS Homo sapiens
305 ZBTB1  
Affinity Capture-MS Homo sapiens
306 POTEF 728378
Affinity Capture-MS Homo sapiens
307 USP36  
Affinity Capture-MS Homo sapiens
308 ASB17  
Affinity Capture-MS Homo sapiens
309 PPP1R12A 4659
Co-fractionation Homo sapiens
310 DCTN4 51164
Affinity Capture-MS Homo sapiens
311 COPS5 10987
Affinity Capture-MS Homo sapiens
312 AGO3  
Affinity Capture-MS Homo sapiens
313 ALK 238
Affinity Capture-MS Homo sapiens
314 NFXL1 152518
Affinity Capture-MS Homo sapiens
315 MYCN  
Affinity Capture-MS Homo sapiens
316 HAUS4  
Affinity Capture-MS Homo sapiens
317 STMN2  
Affinity Capture-MS Homo sapiens
318 TUBA3D 113457
Co-fractionation Homo sapiens
319 HAUS2  
Affinity Capture-MS Homo sapiens
320 EMD 2010
Affinity Capture-MS Homo sapiens
321 HSP90B1 7184
Affinity Capture-MS Homo sapiens
322 CCT5 22948
Affinity Capture-MS Homo sapiens
323 CPVL 54504
Affinity Capture-MS Homo sapiens
324 GCC2 9648
Affinity Capture-MS Homo sapiens
325 PFDN2 5202
Affinity Capture-MS Homo sapiens
326 VCP 7415
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
327 SUMO2 6613
Reconstituted Complex Homo sapiens
328 DCTN1 1639
Affinity Capture-MS Homo sapiens
329 BTK 695
Affinity Capture-MS Homo sapiens
330 CEP76  
Affinity Capture-MS Homo sapiens
331 CDK9 1025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
332 EFNB3 1949
Affinity Capture-MS Homo sapiens
333 H2AFY 9555
Co-fractionation Homo sapiens
334 CEBPA  
Protein-peptide Homo sapiens
335 SSX2IP  
Affinity Capture-MS Homo sapiens
336 DNAJC7 7266
Affinity Capture-MS Homo sapiens
337 ZMYM4  
Affinity Capture-MS Homo sapiens
338 NEURL4  
Affinity Capture-MS Homo sapiens
339 DLEU1  
Two-hybrid Homo sapiens
340 GAN 8139
Affinity Capture-MS Homo sapiens
341 GFER  
Affinity Capture-MS Homo sapiens
342 FANCD2  
Affinity Capture-MS Homo sapiens
343 CUL3 8452
Affinity Capture-MS Homo sapiens
344 RPL23 9349
Affinity Capture-MS Homo sapiens
345 OTUD1 220213
Affinity Capture-MS Homo sapiens
346 LETM1 3954
Affinity Capture-MS Homo sapiens
347 CCT6A 908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
348 CAMSAP3  
Affinity Capture-MS Homo sapiens
349 CTNNB1 1499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
350 ERCC8  
Affinity Capture-MS Homo sapiens
351 CCP110  
Affinity Capture-MS Homo sapiens
352 VARS 7407
Co-fractionation Homo sapiens
353 RPL7 6129
Co-fractionation Homo sapiens
354 TBCD 6904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
355 ADAM22  
Affinity Capture-MS Homo sapiens
356 AKAP8  
Co-fractionation Homo sapiens
357 MAP7D1 55700
Affinity Capture-MS Homo sapiens
358 AGO4  
Affinity Capture-MS Homo sapiens
359 SLAIN2  
Affinity Capture-MS Homo sapiens
360 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
361 NIN 51199
Affinity Capture-MS Homo sapiens
362 TXNL1 9352
Co-fractionation Homo sapiens
363 NUP214 8021
Affinity Capture-MS Homo sapiens
364 TMPRSS5  
Affinity Capture-MS Homo sapiens
365 ZMYM2  
Affinity Capture-MS Homo sapiens
366 ARRB2 409
Affinity Capture-MS Homo sapiens
367 TUBG1 7283
Affinity Capture-MS Homo sapiens
368 INPPL1 3636
Affinity Capture-MS Homo sapiens
369 DNAJA2 10294
Co-fractionation Homo sapiens
370 DSTYK 25778
Affinity Capture-MS Homo sapiens
371 OSTM1 28962
Affinity Capture-MS Homo sapiens
372 CUL5 8065
Affinity Capture-MS Homo sapiens
373 LMAN1 3998
Affinity Capture-MS Homo sapiens
374 GBA 2629
Affinity Capture-MS Homo sapiens
375 EPB41L2 2037
Co-fractionation Homo sapiens
376 TUBB1 81027
Affinity Capture-MS Homo sapiens
377 TUBB4A 10382
Affinity Capture-MS Homo sapiens
378 KIAA1429 25962
Affinity Capture-MS Homo sapiens
379 TERF1 7013
Two-hybrid Homo sapiens
380 EZH2  
Affinity Capture-MS Homo sapiens
381 SLC25A4 291
Co-fractionation Homo sapiens
382 CAD 790
Co-fractionation Homo sapiens
383 AIRE  
Affinity Capture-MS Homo sapiens
384 TRIM31  
Affinity Capture-MS Homo sapiens
385 PINK1  
Affinity Capture-MS Homo sapiens
386 CUL4A 8451
Affinity Capture-MS Homo sapiens
387 C9orf72  
Affinity Capture-MS Homo sapiens
388 NEDD8 4738
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
389 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TUBB4B is involved
PathwayEvidenceSource
Activation of AMPK downstream of NMDARs IEA Reactome
Activation of NMDA receptors and postsynaptic events IEA Reactome
Adaptive Immune System TAS Reactome
Aggrephagy TAS Reactome
Aggrephagy IEA Reactome
Anchoring of the basal body to the plasma membrane TAS Reactome
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Asparagine N-linked glycosylation TAS Reactome
Assembly and cell surface presentation of NMDA receptors IEA Reactome
AURKA Activation by TPX2 TAS Reactome
Autophagy TAS Reactome
Autophagy IEA Reactome
Axon guidance TAS Reactome
Axon guidance IEA Reactome
Carboxyterminal post-translational modifications of tubulin TAS Reactome
Carboxyterminal post-translational modifications of tubulin IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Centrosome maturation TAS Reactome
Chaperonin-mediated protein folding IEA Reactome
Cilium Assembly TAS Reactome
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding IEA Reactome
COPI-dependent Golgi-to-ER retrograde traffic TAS Reactome
COPI-independent Golgi-to-ER retrograde traffic TAS Reactome
COPI-mediated anterograde transport TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
EML4 and NUDC in mitotic spindle formation TAS Reactome
ER to Golgi Anterograde Transport TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
Formation of tubulin folding intermediates by CCT/TriC IEA Reactome
G2/M Transition TAS Reactome
Gap junction assembly IEA Reactome
Gap junction assembly TAS Reactome
Gap junction trafficking IEA Reactome
Gap junction trafficking TAS Reactome
Gap junction trafficking and regulation IEA Reactome
Gap junction trafficking and regulation TAS Reactome
Golgi-to-ER retrograde transport TAS Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
Hedgehog 'off' state TAS Reactome
Hemostasis TAS Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Innate Immune System TAS Reactome
Interferon Signaling TAS Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic TAS Reactome
Intraflagellar transport TAS Reactome
Kinesins TAS Reactome
L1CAM interactions TAS Reactome
L1CAM interactions IEA Reactome
Loss of Nlp from mitotic centrosomes TAS Reactome
Loss of proteins required for interphase microtubule organization from the centrosome TAS Reactome
M Phase TAS Reactome
Macroautophagy TAS Reactome
Macroautophagy IEA Reactome
Membrane Trafficking IEA Reactome
Membrane Trafficking TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of proteins TAS Reactome
MHC class II antigen presentation TAS Reactome
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Mitotic Prometaphase TAS Reactome
Nervous system development TAS Reactome
Nervous system development IEA Reactome
Neuronal System IEA Reactome
Neurotransmitter receptors and postsynaptic signal transmission IEA Reactome
Neutrophil degranulation TAS Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Organelle biogenesis and maintenance TAS Reactome
PKR-mediated signaling TAS Reactome
Post NMDA receptor activation events IEA Reactome
Post-chaperonin tubulin folding pathway IEA Reactome
Post-translational protein modification TAS Reactome
Post-translational protein modification IEA Reactome
Prefoldin mediated transfer of substrate to CCT/TriC IEA Reactome
Protein folding IEA Reactome
Recruitment of mitotic centrosome proteins and complexes TAS Reactome
Recruitment of NuMA to mitotic centrosomes TAS Reactome
Recycling pathway of L1 TAS Reactome
Recycling pathway of L1 IEA Reactome
Regulation of PLK1 Activity at G2/M Transition TAS Reactome
Resolution of Sister Chromatid Cohesion TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases Activate Formins TAS Reactome
RHO GTPases activate IQGAPs TAS Reactome
Sealing of the nuclear envelope (NE) by ESCRT-III TAS Reactome
Selective autophagy TAS Reactome
Selective autophagy IEA Reactome
Separation of Sister Chromatids TAS Reactome
Signal Transduction TAS Reactome
Signaling by Hedgehog TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
The role of GTSE1 in G2/M progression after G2 checkpoint TAS Reactome
Translocation of SLC2A4 (GLUT4) to the plasma membrane IEA Reactome
Transmission across Chemical Synapses IEA Reactome
Transport of connexons to the plasma membrane TAS Reactome
Transport to the Golgi and subsequent modification TAS Reactome
Vesicle-mediated transport IEA Reactome
Vesicle-mediated transport TAS Reactome
Viral Infection Pathways TAS Reactome





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