Gene description for CRK
Gene name v-crk avian sarcoma virus CT10 oncogene homolog
Gene symbol CRK
Other names/aliases CRKII
p38
Species Homo sapiens
 Database cross references - CRK
ExoCarta ExoCarta_1398
Vesiclepedia VP_1398
Entrez Gene 1398
HGNC 2362
MIM 164762
UniProt P46108  
 CRK identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Urine 19056867    
 Gene ontology annotations for CRK
Molecular Function
    phosphotyrosine residue binding GO:0001784 IPI
    insulin-like growth factor receptor binding GO:0005159 IEA
    protein binding GO:0005515 IPI
    cytoskeletal protein binding GO:0008092 IEA
    SH3 domain binding GO:0017124 IPI
    kinase binding GO:0019900 IPI
    signaling receptor complex adaptor activity GO:0030159 IEA
    receptor tyrosine kinase binding GO:0030971 IBA
    ubiquitin protein ligase binding GO:0031625 IEA
    signaling adaptor activity GO:0035591 IBA
    signaling adaptor activity GO:0035591 IDA
    SH2 domain binding GO:0042169 IPI
    protein phosphorylated amino acid binding GO:0045309 IDA
    ephrin receptor binding GO:0046875 IPI
    scaffold protein binding GO:0097110 IEA
    protein tyrosine kinase binding GO:1990782 IPI
Biological Process
    neuron migration GO:0001764 IEA
    response to yeast GO:0001878 IEA
    regulation of transcription by RNA polymerase II GO:0006357 TAS
    lipid metabolic process GO:0006629 IEA
    enzyme-linked receptor protein signaling pathway GO:0007167 IBA
    cell population proliferation GO:0008283 IEA
    regulation of cell shape GO:0008360 IMP
    regulation of signal transduction GO:0009966 IDA
    positive regulation of smooth muscle cell migration GO:0014911 IEA
    dendrite development GO:0016358 IEA
    cell migration GO:0016477 IBA
    hippocampus development GO:0021766 IEA
    cerebral cortex development GO:0021987 IEA
    establishment of cell polarity GO:0030010 IEA
    actin cytoskeleton organization GO:0030036 IMP
    positive regulation of cell growth GO:0030307 IDA
    regulation of actin cytoskeleton organization GO:0032956 IDA
    regulation of cell adhesion mediated by integrin GO:0033628 IEA
    positive regulation of Rac protein signal transduction GO:0035022 IEA
    helper T cell diapedesis GO:0035685 IEA
    response to hepatocyte growth factor GO:0035728 IEA
    reelin-mediated signaling pathway GO:0038026 IEA
    response to hydrogen peroxide GO:0042542 IEA
    regulation of GTPase activity GO:0043087 IDA
    negative regulation of natural killer cell mediated cytotoxicity GO:0045953 IEA
    positive regulation of JNK cascade GO:0046330 IEA
    ephrin receptor signaling pathway GO:0048013 IDA
    regulation of dendrite development GO:0050773 IEA
    cell chemotaxis GO:0060326 IEA
    regulation of wound healing GO:0061041 IDA
    negative regulation of wound healing GO:0061045 IDA
    negative regulation of wound healing GO:0061045 IMP
    response to cholecystokinin GO:0061847 IEA
    cellular response to transforming growth factor beta stimulus GO:0071560 IEA
    cellular response to nitric oxide GO:0071732 IEA
    protein localization to membrane GO:0072657 IEA
    postsynaptic specialization assembly GO:0098698 IEA
    cerebellar neuron development GO:0098749 IEA
    positive regulation of substrate adhesion-dependent cell spreading GO:1900026 IMP
    response to peptide GO:1901652 IEA
    regulation of intracellular signal transduction GO:1902531 IDA
    positive regulation of skeletal muscle acetylcholine-gated channel clustering GO:1904395 IEA
    cellular response to nerve growth factor stimulus GO:1990090 IEA
    cellular response to insulin-like growth factor stimulus GO:1990314 IEA
    cellular response to endothelin GO:1990859 IEA
    regulation of cell motility GO:2000145 IDA
    negative regulation of cell motility GO:2000146 IDA
    negative regulation of cell motility GO:2000146 IMP
    regulation of T cell migration GO:2000404 IEA
Subcellular Localization
    nucleus GO:0005634 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IC
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IEA
    actin cytoskeleton GO:0015629 IEA
    membrane GO:0016020 ISS
    neuromuscular junction GO:0031594 IEA
    protein-containing complex GO:0032991 IPI
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CRK in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
9
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
13
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CRK
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRT76 51350
Affinity Capture-MS Homo sapiens
2 KRT77 374454
Affinity Capture-MS Homo sapiens
3 SLC25A13 10165
Affinity Capture-MS Homo sapiens
4 KRT4 3851
Affinity Capture-MS Homo sapiens
5 KRT73 319101
Affinity Capture-MS Homo sapiens
6 ABL2  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 AP2B1 163
Affinity Capture-MS Homo sapiens
8 RNGTT 8732
Affinity Capture-MS Homo sapiens
9 LYZ 4069
Affinity Capture-MS Homo sapiens
10 KRT6B 3854
Affinity Capture-MS Homo sapiens
11 KRT1 3848
Affinity Capture-MS Homo sapiens
12 SHC1 6464
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
13 POT1  
Two-hybrid Homo sapiens
14 BUB1  
Two-hybrid Homo sapiens
15 STAT5A 6776
Co-localization Homo sapiens
16 RIN3  
Affinity Capture-MS Homo sapiens
17 KRT6A 3853
Affinity Capture-MS Homo sapiens
18 KRT17 3872
Affinity Capture-MS Homo sapiens
19 PHLPP1  
Proximity Label-MS Homo sapiens
20 SOS1 6654
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
21 SERPINB6 5269
Affinity Capture-MS Homo sapiens
22 HSPA1L 3305
Affinity Capture-MS Homo sapiens
23 TSG101 7251
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
24 ARHGAP42  
Affinity Capture-MS Homo sapiens
25 SOCS1  
Reconstituted Complex Homo sapiens
26 UBC 7316
Affinity Capture-MS Homo sapiens
27 CSE1L 1434
Affinity Capture-Western Homo sapiens
28 TERF2IP 54386
Two-hybrid Homo sapiens
29 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
30 RET 5979
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
31 PTPN1 5770
Reconstituted Complex Homo sapiens
32 PLG 5340
Affinity Capture-MS Homo sapiens
33 HSPA5 3309
Affinity Capture-MS Homo sapiens
34 PIK3CD 5293
Affinity Capture-MS Homo sapiens
35 DPPA4  
Two-hybrid Homo sapiens
36 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
37 MRPL48  
Affinity Capture-MS Homo sapiens
38 TUBB 203068
Affinity Capture-MS Homo sapiens
39 GFPT1 2673
Co-fractionation Homo sapiens
40 AP2A1 160
Affinity Capture-MS Homo sapiens
41 ZAP70 7535
Reconstituted Complex Homo sapiens
42 SH3BP1 23616
Reconstituted Complex Homo sapiens
43 PTPN4  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
44 SRC 6714
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
45 MAP4K5 11183
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
46 KHDRBS1 10657
Reconstituted Complex Homo sapiens
47 PSMC6 5706
Two-hybrid Homo sapiens
48 MICAL1 64780
Reconstituted Complex Homo sapiens
49 RPS5 6193
Affinity Capture-MS Homo sapiens
50 ARHGEF10 9639
Affinity Capture-MS Homo sapiens
51 KRT5 3852
Affinity Capture-MS Homo sapiens
52 KRT12 3859
Affinity Capture-MS Homo sapiens
53 KRT78 196374
Affinity Capture-MS Homo sapiens
54 SERPINH1 871
Co-fractionation Homo sapiens
55 PEAK1 79834
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 BCOR  
Proximity Label-MS Homo sapiens
57 ELMO2 63916
Affinity Capture-MS Homo sapiens
58 DDX6 1656
Affinity Capture-MS Homo sapiens
59 SFN 2810
Affinity Capture-MS Homo sapiens
60 HSPA6 3310
Affinity Capture-MS Homo sapiens
61 DOCK1 1793
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
62 ARPC1B 10095
Affinity Capture-MS Homo sapiens
63 YWHAG 7532
Affinity Capture-MS Homo sapiens
64 CBLB 868
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 MAPK4  
Two-hybrid Homo sapiens
66 BUD31 8896
Co-fractionation Homo sapiens
67 ERBB2 2064
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
68 FGFR1 2260
Co-localization Homo sapiens
69 USP53 54532
Two-hybrid Homo sapiens
70 EEF1A1 1915
Affinity Capture-MS Homo sapiens
71 TRIM15  
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
72 PRNP 5621
Affinity Capture-MS Homo sapiens
73 FAM154A  
Two-hybrid Homo sapiens
74 DSC1 1823
Affinity Capture-MS Homo sapiens
75 AGO2 27161
Affinity Capture-MS Homo sapiens
76 HSPA9 3313
Affinity Capture-MS Homo sapiens
77 EDC4 23644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 KRT8 3856
Affinity Capture-MS Homo sapiens
79 NEDD9 4739
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
80 PPP1CA 5499
Two-hybrid Homo sapiens
81 BCAR1 9564
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
82 KIT 3815
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
83 FASLG 356
Protein-peptide Homo sapiens
84 RPS19 6223
Affinity Capture-MS Homo sapiens
85 PLSCR1 5359
Two-hybrid Homo sapiens
86 PRPH 5630
Proximity Label-MS Homo sapiens
87 NCKIPSD 51517
Affinity Capture-MS Homo sapiens
88 PDGFRB 5159
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
89 ERBB3 2065
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
90 KRT24 192666
Affinity Capture-MS Homo sapiens
91 DCP2  
Affinity Capture-MS Homo sapiens
92 TUBA1A 7846
Affinity Capture-MS Homo sapiens
93 CBL 867
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
94 CAST 831
Co-fractionation Homo sapiens
95 ARAP1 116985
Affinity Capture-MS Homo sapiens
96 C12orf49  
Positive Genetic Homo sapiens
97 UBASH3B 84959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 CDH1 999
Proximity Label-MS Homo sapiens
99 FLT1 2321
Co-localization Homo sapiens
100 FUBP1 8880
Co-fractionation Homo sapiens
101 PIK3CB 5291
Affinity Capture-MS Homo sapiens
102 DDX5 1655
Affinity Capture-MS Homo sapiens
103 CRKL 1399
Negative Genetic Homo sapiens
104 SPR 6697
Co-fractionation Homo sapiens
105 KRT9 3857
Affinity Capture-MS Homo sapiens
106 KRT14 3861