Gene ontology annotations for KRT79
Experiment description of studies that identified KRT79 in exosomes
1
Experiment ID
21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
PubMed ID
19837982
Organism
Homo sapiens
Experiment description
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors
"Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name
MCP
Publication year
2009
Sample
Colorectal cancer cells
Sample name
LIM1215
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.10-1.12 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [Orbitrap] Western blotting
2
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
6
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
7
Experiment ID
146
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
PubMed ID
22723089
Organism
Homo sapiens
Experiment description
Prostate cancer cell derived exosomes
Authors
"Hosseini-Beheshti E, Guns ES."
Journal name
MCP
Publication year
2012
Sample
Prostate cancer cells
Sample name
RWPE - Rep 2
Isolation/purification methods
Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [QTOF]
8
Experiment ID
66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19199708
Organism
Homo sapiens
Experiment description
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors
"Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name
JPR
Publication year
2009
Sample
Saliva
Sample name
Saliva
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy
9
Experiment ID
191
MISEV standards
✘
Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for KRT79
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ppp2r1a
51792
Affinity Capture-MS
Mus musculus
2
BAG3
9531
Affinity Capture-Luminescence
Homo sapiens
3
KRT18
3875
Two-hybrid
Homo sapiens
4
KRT84
3890
Cross-Linking-MS (XL-MS)
Homo sapiens
5
BTRC
8945
Affinity Capture-MS
Homo sapiens
6
KRT27
342574
Two-hybrid
Homo sapiens
7
LGR4
55366
Affinity Capture-MS
Homo sapiens
8
KRT36
8689
Two-hybrid
Homo sapiens
9
KRT25
147183
Two-hybrid
Homo sapiens
10
KRT33B
3884
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
11
CBL
867
Affinity Capture-MS
Homo sapiens
12
INPPL1
3636
Affinity Capture-MS
Homo sapiens
13
KRT6A
3853
Cross-Linking-MS (XL-MS)
Homo sapiens
14
KRT35
3886
Two-hybrid
Homo sapiens
15
CRK
1398
Affinity Capture-MS
Homo sapiens
16
KRT34
Two-hybrid
Homo sapiens
17
PDHA1
5160
Proximity Label-MS
Homo sapiens
18
EPS15
2060
Affinity Capture-MS
Homo sapiens
19
NHLRC2
374354
Affinity Capture-MS
Homo sapiens
20
KRT28
162605
Two-hybrid
Homo sapiens
21
HNRNPA1
3178
Affinity Capture-MS
Homo sapiens
22
SIRT1
Affinity Capture-MS
Homo sapiens
23
Cep152
Affinity Capture-MS
Mus musculus
24
TRIM54
Two-hybrid
Homo sapiens
25
TFCP2
7024
Affinity Capture-MS
Homo sapiens
26
AP2M1
1173
Affinity Capture-MS
Homo sapiens
27
KRT15
3866
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
28
KRT24
192666
Two-hybrid
Homo sapiens
29
UBASH3B
84959
Affinity Capture-MS
Homo sapiens
30
KRT20
54474
Cross-Linking-MS (XL-MS)
Homo sapiens
31
KRT38
8687
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
32
Dctn3
Affinity Capture-MS
Mus musculus
33
EVI5L
Two-hybrid
Homo sapiens
34
KRT75
9119
Cross-Linking-MS (XL-MS)
Homo sapiens
35
KRT13
3860
Two-hybrid
Homo sapiens
36
KRT14
3861
Two-hybrid
Homo sapiens
37
PIK3R2
5296
Affinity Capture-MS
Homo sapiens
38
USHBP1
Two-hybrid
Homo sapiens
39
SYCE3
Two-hybrid
Homo sapiens
40
KRT19
3880
Two-hybrid
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
41
KRT5
3852
Cross-Linking-MS (XL-MS)
Homo sapiens
42
YAP1
10413
Affinity Capture-MS
Homo sapiens
43
KRT31
3881
Two-hybrid
Homo sapiens
44
KRT16
3868
Two-hybrid
Homo sapiens
45
KIF2C
11004
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which KRT79 is involved