Gene description for KRT35
Gene name keratin 35, type I
Gene symbol KRT35
Other names/aliases HA5
Ha-5
KRTHA5
hHa5
Species Homo sapiens
 Database cross references - KRT35
ExoCarta ExoCarta_3886
Vesiclepedia VP_3886
Entrez Gene 3886
HGNC 6453
MIM 602764
UniProt Q92764  
 KRT35 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for KRT35
Molecular Function
    structural molecule activity GO:0005198 IEA
Biological Process
    anatomical structure morphogenesis GO:0009653 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    intermediate filament GO:0005882 IEA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified KRT35 in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
EV Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for KRT35
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDC25B 994
Affinity Capture-MS Homo sapiens
2 DLG3 1741
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KRT35 is involved
No pathways found





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