Gene description for TBC1D30
Gene name TBC1 domain family, member 30
Gene symbol TBC1D30
Other names/aliases -
Species Homo sapiens
 Database cross references - TBC1D30
ExoCarta ExoCarta_23329
Entrez Gene 23329
HGNC 29164
MIM 615077
UniProt Q9Y2I9  
 TBC1D30 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for TBC1D30
Molecular Function
    GTPase activator activity GO:0005096 IDA
    Rab GTPase binding GO:0017137 IPI
Biological Process
    negative regulation of cilium assembly GO:1902018 IMP
    positive regulation of GTPase activity GO:0043547 IDA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    ciliary basal body GO:0036064 IDA
    primary cilium GO:0072372 IDA
 Experiment description of studies that identified TBC1D30 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for TBC1D30
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TBC1D30 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here