Gene description for SCOC
Gene name short coiled-coil protein
Gene symbol SCOC
Other names/aliases HRIHFB2072
SCOCO
Species Homo sapiens
 Database cross references - SCOC
ExoCarta ExoCarta_60592
Entrez Gene 60592
HGNC 20335
UniProt Q9UIL1  
 SCOC identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for SCOC
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of macroautophagy GO:0016239 IDA
Subcellular Localization
    endosome GO:0005768 IDA
    cytosol GO:0005829 IEA
    Golgi membrane GO:0000139 IEA
    trans-Golgi network GO:0005802 IDA
 Experiment description of studies that identified SCOC in exosomes
1
Experiment ID 275
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for SCOC
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SCOC is involved
No pathways found





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