Gene description for RPS6KA4
Gene name	ribosomal protein S6 kinase, 90kDa, polypeptide 4
Gene symbol	RPS6KA4
Other names/aliases	MSK2 RSK-B
Species	Homo sapiens
Database cross references - RPS6KA4
ExoCarta	ExoCarta_8986
Entrez Gene	8986
HGNC	10433
MIM	603606
UniProt	O75676
RPS6KA4 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for RPS6KA4

Molecular Function     ATP binding GO:0005524 IDA     magnesium ion binding GO:0000287 IEA     mitogen-activated protein kinase p38 binding GO:0048273 IGI     protein binding GO:0005515 IPI     protein serine/threonine kinase activity GO:0004674 IMP     ribosomal protein S6 kinase activity GO:0004711 NAS Biological Process     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP     regulation of transcription, DNA-templated GO:0006355 IDA     histone phosphorylation GO:0016572 TAS     inflammatory response GO:0006954 IEA     positive regulation of CREB transcription factor activity GO:0032793 TAS     intracellular signal transduction GO:0035556 IDA     positive regulation of histone acetylation GO:0035066 IMP     positive regulation of histone phosphorylation GO:0033129 IMP     axon guidance GO:0007411 TAS     histone H3-S10 phosphorylation GO:0043987 IMP     interleukin-1-mediated signaling pathway GO:0070498 IMP     histone H3-S28 phosphorylation GO:0043988 IMP     negative regulation of cytokine production GO:0001818 TAS     protein phosphorylation GO:0006468 IDA     positive regulation of NF-kappaB transcription factor activity GO:0051092 TAS Subcellular Localization     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     nucleoplasm GO:0005654 IDA