Gene description for HSP90AB3P |
Gene name |
heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene |
Gene symbol |
HSP90AB3P |
Other names/aliases |
HSP90BC HSPCP1 |
Species |
Homo sapiens |
Database cross references - HSP90AB3P |
ExoCarta |
ExoCarta_3327 |
Entrez Gene |
3327 |
HGNC |
5259 |
HSP90AB3P identified in exosomes derived from the following tissue/cell type |
Colorectal cancer cells
|
17956143
|
Endothelial cells
|
26027894
|
Hepatocellular carcinoma cells
|
26054723
|
Gene ontology annotations for HSP90AB3P |
|
Experiment description of studies that identified HSP90AB3P in exosomes |
1 |
Experiment ID |
20 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSP90
|
EV Cytosolic markers |
✔
CD63|CD81|LAMP1
|
EV Membrane markers |
✔
GOLGA2|cytochrome c
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17956143
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of microvesicles derived from human colorectal cancer cells. |
Authors |
Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS |
Journal name |
JPR
|
Publication year |
2007 |
Sample |
Colorectal cancer cells |
Sample name |
HT29 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density |
1.16 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LTQ] Western blotting |
|
|
2 |
Experiment ID |
226 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
GAPDH
|
EV Cytosolic markers |
✔
CD9|FLOT1
|
EV Membrane markers |
✔
LMNA|H2AFX|ATP5A1|TOMM20
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
mRNA
|
Identification method |
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
|
PubMed ID |
26027894
|
Organism |
Homo sapiens |
Experiment description |
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting |
Authors |
Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar |
Journal name |
Journal of Extracellular Vesicles
|
Publication year |
2015 |
Sample |
Endothelial cells |
Sample name |
HMEC-1 |
Isolation/purification methods |
Differential ultracentrifugation Sucrose density gradient |
Flotation density |
1.10 g/mL
|
Molecules identified in the study |
miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA |
Methods used in the study |
Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting |
|
|
3 |
Experiment ID |
234 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|HSC70|GAPDH
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✔
HSP90B1
|
EV Negative markers |
✔
qNano
|
EV Particle analysis
|
|
Identified molecule |
mRNA
|
Identification method |
RNA Sequencing
|
PubMed ID |
26054723
|
Organism |
Homo sapiens |
Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
Authors |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N |
Journal name |
Carcinogenesis
|
Publication year |
2015 |
Sample |
Hepatocellular carcinoma cells |
Sample name |
HKCI-C3 |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein RNA |
Methods used in the study |
Western blotting Mass spectrometry RT-PCR RNA Sequencing |
|
|
Protein-protein interactions for HSP90AB3P |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which HSP90AB3P is involved |
No pathways found
|
|
|