Gene description for ANKMY2
Gene name ankyrin repeat and MYND domain containing 2
Gene symbol ANKMY2
Other names/aliases ZMYND20
Species Homo sapiens
 Database cross references - ANKMY2
ExoCarta ExoCarta_57037
Vesiclepedia VP_57037
Entrez Gene 57037
HGNC 25370
UniProt Q8IV38  
 ANKMY2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ANKMY2
Molecular Function
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 IEA
    metal ion binding GO:0046872 IEA
Subcellular Localization
    cilium GO:0005929 IEA
 Experiment description of studies that identified ANKMY2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ANKMY2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACD  
Two-hybrid Homo sapiens
2 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 POT1  
Two-hybrid Homo sapiens
4 ADCY3 109
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 FBXL6  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
6 HSF1  
Co-fractionation Homo sapiens
7 TRPV5  
Affinity Capture-MS Homo sapiens
8 SNX4 8723
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 STAT5B 6777
Co-fractionation Homo sapiens
10 DNAAF1  
Affinity Capture-MS Homo sapiens
11 METTL13 51603
Co-fractionation Homo sapiens
12 DUSP8  
Affinity Capture-MS Homo sapiens
13 ADCY9 115
Affinity Capture-MS Homo sapiens
14 KLHL26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 GADL1  
Affinity Capture-MS Homo sapiens
16 PBDC1 51260
Co-fractionation Homo sapiens
17 SPSB4  
Affinity Capture-MS Homo sapiens
18 KANSL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SSB 6741
Co-fractionation Homo sapiens
20 FKBP8 23770
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 GUCY1B3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ADCY8  
Affinity Capture-MS Homo sapiens
23 SPSB2  
Affinity Capture-MS Homo sapiens
24 PLD5  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
25 RPS6KB2  
Affinity Capture-MS Homo sapiens
26 TUBB1 81027
Affinity Capture-MS Homo sapiens
27 PLD1 5337
Affinity Capture-Western Homo sapiens
28 Cep152  
Affinity Capture-MS Mus musculus
29 ARFGEF2 10564
Co-fractionation Homo sapiens
30 HSP90AB3P 3327
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 HNRNPF 3185
Co-fractionation Homo sapiens
32 SURF2  
Co-fractionation Homo sapiens
33 FKBP5 2289
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
34 AGO4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 AARS 16
Co-fractionation Homo sapiens
36 SERBP1 26135
Affinity Capture-MS Homo sapiens
37 CTSC 1075
Co-fractionation Homo sapiens
38 LRSAM1 90678
Co-fractionation Homo sapiens
39 ADCY2 108
Affinity Capture-MS Homo sapiens
40 ADCY6 112
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 DHPS 1725
Co-fractionation Homo sapiens
42 PARP6  
Co-fractionation Homo sapiens
43 PLIN3 10226
Co-fractionation Homo sapiens
44 SKIV2L2 23517
Co-fractionation Homo sapiens
45 PTGES3 10728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 AGO3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 KIF5C 3800
Co-fractionation Homo sapiens
48 CTNNA1 1495
Co-fractionation Homo sapiens
49 DTD1 92675
Co-fractionation Homo sapiens
50 TINF2  
Two-hybrid Homo sapiens
51 GUCY1A3  
Affinity Capture-MS Homo sapiens
52 PLD2 5338
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 RPRD1A  
Co-fractionation Homo sapiens
54 ARIH1 25820
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which ANKMY2 is involved
No pathways found





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