Gene description for CTSC
Gene name	cathepsin C
Gene symbol	CTSC
Other names/aliases	CPPI DPP-I DPP1 DPPI HMS JP JPD PALS PDON1 PLS
Species	Homo sapiens
Database cross references - CTSC
ExoCarta	ExoCarta_1075
Entrez Gene	1075
HGNC	2528
MIM	602365
UniProt	P53634
CTSC identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Saliva	19199708
Urine	19056867

Gene ontology annotations for CTSC

Molecular Function     cysteine-type endopeptidase activity GO:0004197 IBA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IEA     chaperone binding GO:0051087 ISS     cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 IBA     phosphatase binding GO:0019902 ISS     serine-type endopeptidase activity GO:0004252 IEA     chloride ion binding GO:0031404 IEA     cysteine-type peptidase activity GO:0008234 IDA     protein self-association GO:0043621 IEA Biological Process     proteolysis involved in cellular protein catabolic process GO:0051603 IBA     response to organic substance GO:0010033 IEA     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 IBA     positive regulation of apoptotic signaling pathway GO:2001235 IBA     positive regulation of peptidase activity GO:0010952 IBA     immune response GO:0006955 TAS     positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 ISS     T cell mediated cytotoxicity GO:0001913 IEA     aging GO:0007568 IEA     proteolysis GO:0006508 IDA Subcellular Localization     extracellular exosome GO:0070062 IDA     Golgi apparatus GO:0005794 IEA     lysosome GO:0005764 TAS     membrane GO:0016020 IDA     endoplasmic reticulum GO:0005783 IEA     extracellular space GO:0005615 IDA