Gene description for GBA
Gene name	glucosidase, beta, acid
Gene symbol	GBA
Other names/aliases	GBA1 GCB GLUC
Species	Homo sapiens
Database cross references - GBA
ExoCarta	ExoCarta_2629
Entrez Gene	2629
HGNC	4177
MIM	606463
UniProt	P04062
GBA identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for GBA

Molecular Function     protein binding GO:0005515 IPI     glucosylceramidase activity GO:0004348 IMP     receptor binding GO:0005102 ISS Biological Process     glycosphingolipid metabolic process GO:0006687 TAS     skin morphogenesis GO:0043589 IEA     negative regulation of interleukin-6 production GO:0032715 IDA     sphingolipid metabolic process GO:0006665 TAS     carbohydrate metabolic process GO:0005975 IEA     negative regulation of inflammatory response GO:0050728 IC     response to glucocorticoid GO:0051384 IEA     sphingosine biosynthetic process GO:0046512 IMP     negative regulation of MAP kinase activity GO:0043407 IMP     response to thyroid hormone GO:0097066 IEA     positive regulation of protein dephosphorylation GO:0035307 IMP     ceramide biosynthetic process GO:0046513 IMP     response to pH GO:0009268 IEA     glucosylceramide catabolic process GO:0006680 IMP     response to testosterone GO:0033574 IEA     termination of signal transduction GO:0023021 IMP     cellular response to tumor necrosis factor GO:0071356 IMP     response to estrogen GO:0043627 IEA     positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 IMP     small molecule metabolic process GO:0044281 TAS     regulation of water loss via skin GO:0033561 IEA Subcellular Localization     extracellular exosome GO:0070062 IDA     lysosomal lumen GO:0043202 ISS     lysosomal membrane GO:0005765 TAS