Gene description for MYH13
Gene name myosin, heavy chain 13, skeletal muscle
Gene symbol MYH13
Other names/aliases MyHC-IIL
MyHC-eo
Species Homo sapiens
 Database cross references - MYH13
ExoCarta ExoCarta_8735
Entrez Gene 8735
HGNC 7571
MIM 603487
UniProt Q9UKX3  
 MYH13 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for MYH13
Molecular Function
    microfilament motor activity GO:0000146 TAS
    ATP binding GO:0005524 IEA
    calmodulin binding GO:0005516 IEA
    actin binding GO:0003779 IEA
Biological Process
    muscle contraction GO:0006936 TAS
    metabolic process GO:0008152 TAS
    cellular response to starvation GO:0009267 IEA
Subcellular Localization
    myofibril GO:0030016 IEA
    extracellular exosome GO:0070062 IDA
    muscle myosin complex GO:0005859 TAS
    myosin filament GO:0032982 IEA
 Experiment description of studies that identified MYH13 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for MYH13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LSM7  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MYH13 is involved
PathwayEvidenceSource
Translocation of GLUT4 to the plasma membrane TAS Reactome





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