Experiment description of studies that identified LYST in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for LYST

Protein Interactor ExoCarta ID Identification method PubMed Species 1 LLGL2 3993 Affinity Capture-MS Homo sapiens 2 MYCN   Affinity Capture-MS Homo sapiens 3 DGCR14   Two-hybrid Homo sapiens 4 HNRNPH2 3188 Affinity Capture-MS Homo sapiens 5 CSNK2B 1460 Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 6 MYH13 8735 Affinity Capture-MS Homo sapiens 7 DAP3 7818 Affinity Capture-MS Homo sapiens 8 GAR1 54433 Affinity Capture-MS Homo sapiens 9 MRPL17   Two-hybrid Homo sapiens 10 YWHAB 7529 Two-hybrid Homo sapiens 11 ECT2 1894 Affinity Capture-MS Homo sapiens 12 Dync1li1 235661 Affinity Capture-MS Mus musculus 13 DNAJC14   Two-hybrid Homo sapiens 14 KLC3   Affinity Capture-MS Homo sapiens 15 CENPJ 55835 Two-hybrid Homo sapiens 16 KPNB1 3837 Two-hybrid Homo sapiens 17 MRPS31   Two-hybrid Homo sapiens 18 HNRNPM 4670 Two-hybrid Homo sapiens 19 YWHAZ 7534 Reconstituted Complex Homo sapiens 20 EFS   Two-hybrid Homo sapiens 21 PPIA 5478 Affinity Capture-MS Homo sapiens 22 MLH1 4292 Affinity Capture-MS Homo sapiens 23 SAP30 8819 Affinity Capture-MS Homo sapiens 24 VTA1 51534 Two-hybrid Homo sapiens 25 ATN1   Two-hybrid Homo sapiens 26 NCDN 23154 Two-hybrid Homo sapiens 27 YWHAQ 10971 Two-hybrid Homo sapiens 28 PLS1 5357 Cross-Linking-MS (XL-MS) Homo sapiens 29 PCBP4 57060 Two-hybrid Homo sapiens 30 CELF4   Two-hybrid Homo sapiens 31 MED12   Two-hybrid Homo sapiens 32 ZNF521   Two-hybrid Homo sapiens 33 MYC   Affinity Capture-MS Homo sapiens 34 Vamp2   Affinity Capture-MS Mus musculus 35 CNTROB   Two-hybrid Homo sapiens 36 ESRRA   Two-hybrid Homo sapiens 37 RAB7A 7879 Proximity Label-MS Homo sapiens 38 HGS 9146 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 39 Cep85l   Affinity Capture-MS Mus musculus 40 TACC1 6867 Affinity Capture-MS Homo sapiens 41 Tnpo1 238799 Affinity Capture-MS Mus musculus 42 ANAPC4 29945 Affinity Capture-MS Homo sapiens 43 TNNI3   Two-hybrid Homo sapiens 44 KIF1C 10749 Affinity Capture-MS Homo sapiens 45 Ccdc9   Affinity Capture-MS Mus musculus View the network

Pathways in which LYST is involved

No pathways found