Gene description for YWHAQ
Gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
Gene symbol YWHAQ
Other names/aliases 14-3-3
1C5
HS1
Species Homo sapiens
 Database cross references - YWHAQ
ExoCarta ExoCarta_10971
Vesiclepedia VP_10971
Entrez Gene 10971
HGNC 12854
MIM 609009
UniProt P27348  
 YWHAQ identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Keratinocytes 19530224    
Keratinocytes 19530224    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for YWHAQ
Molecular Function
    protein binding GO:0005515 IPI
    protein domain specific binding GO:0019904 IEA
    identical protein binding GO:0042802 IPI
    transmembrane transporter binding GO:0044325 IEA
    14-3-3 protein binding GO:0071889 IEA
Biological Process
    protein targeting GO:0006605 IEA
    signal transduction GO:0007165 IBA
    small GTPase-mediated signal transduction GO:0007264 IEA
    protein localization GO:0008104 IBA
    substantia nigra development GO:0021762 HEP
    negative regulation of monoatomic ion transmembrane transport GO:0034766 IEA
    negative regulation of DNA-templated transcription GO:0045892 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified YWHAQ in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
18
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
19
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
24
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
47
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
48
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
53
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
54
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
56
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
60
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
61
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
62
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
63
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
64
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
65
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
66
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
67
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
68
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
69
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
70
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
71
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
72
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
73
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
74
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
75
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
76
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
77
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
78
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
79
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
80
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
81
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
82
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
83
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
84
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for YWHAQ
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mdm2  
Affinity Capture-MS Mus musculus
2 HDAC4  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
3 ARHGEF2 9181
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
4 KRT1 3848
Affinity Capture-MS Homo sapiens
5 LNP1  
Affinity Capture-MS Homo sapiens
6 RALGPS2 55103
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TBC1D4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 LDHB 3945
Co-fractionation Homo sapiens
9 RIN3  
Affinity Capture-MS Homo sapiens
10 SH3BP4 23677
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SUCO  
Affinity Capture-MS Homo sapiens
12 DYNC1I2 1781
Proximity Label-MS Homo sapiens
13 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
14 CRK 1398
Affinity Capture-MS Homo sapiens
15 NFATC1 4772
Reconstituted Complex Homo sapiens
16 MIIP 60672
Affinity Capture-MS Homo sapiens
17 EMD 2010
Affinity Capture-MS Homo sapiens
18 MAP4 4134
Co-fractionation Homo sapiens
19 CDC25B 994
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
20 SLC25A1 6576
Affinity Capture-MS Homo sapiens
21 CSE1L 1434
Reconstituted Complex Homo sapiens
22 PARK7 11315
Affinity Capture-MS Homo sapiens
23 GCN1L1 10985
Reconstituted Complex Homo sapiens
24 VASP 7408
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
25 CKB 1152
Co-fractionation Homo sapiens
26 WDR62  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 MAP3K5 4217
Reconstituted Complex Homo sapiens
28 HDAC3 8841
Affinity Capture-Western Homo sapiens
29 ARL3 403
Affinity Capture-MS Homo sapiens
30 PFKL 5211
Reconstituted Complex Homo sapiens
31 KLC1 3831
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
32 ACTN2 88
Affinity Capture-MS Homo sapiens
33 CHAF1A  
Reconstituted Complex Homo sapiens
34 KIF23 9493
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 PLCH1  
Affinity Capture-MS Homo sapiens
36 ERC1 23085
Affinity Capture-MS Homo sapiens
37 HSPH1 10808
Co-fractionation Homo sapiens
38 PIK3C3 5289
Reconstituted Complex Homo sapiens
39 NCOA3  
Reconstituted Complex Homo sapiens
40 MYH7 4625
Affinity Capture-MS Homo sapiens
41 FAM86C1  
Affinity Capture-MS Homo sapiens
42 ARHGAP19  
Affinity Capture-MS Homo sapiens
43 SYDE2  
Affinity Capture-MS Homo sapiens
44 SFN 2810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
45 RIPK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
46 Wwtr1  
Affinity Capture-MS Mus musculus
47 RCOR3  
Two-hybrid Homo sapiens
48 RASGRP3  
Affinity Capture-MS Homo sapiens
49 ARHGEF4  
Affinity Capture-MS Homo sapiens
50 EEF1A1 1915
Affinity Capture-MS Homo sapiens
51 CKM  
Reconstituted Complex Homo sapiens
52 RNF11 26994
Affinity Capture-Western Homo sapiens
53 PPIP5K2 23262
Affinity Capture-MS Homo sapiens
54 CLASP2 23122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 HAT1 8520
Reconstituted Complex Homo sapiens
56 SUV420H1  
Affinity Capture-MS Homo sapiens
57 RASSF2 9770
Affinity Capture-MS Homo sapiens
58 CHMP4C 92421
Affinity Capture-MS Homo sapiens
59 ATG9A 79065
Affinity Capture-MS Homo sapiens
60 TCP1 6950
Reconstituted Complex Homo sapiens
61 SPTA1  
Reconstituted Complex Homo sapiens
62 WNK1 65125
Affinity Capture-MS Homo sapiens
63 MAP3K2 10746
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 CRY1  
Affinity Capture-MS Homo sapiens
65 PKP2 5318
Affinity Capture-Western Homo sapiens
66 PPP1R3D  
Affinity Capture-MS Homo sapiens
67 SRSF3 6428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 RRAS2 22800
Affinity Capture-MS Homo sapiens
69 HDAC7  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
70 ESRRB  
Affinity Capture-MS Homo sapiens
71 SMTNL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 YAP1 10413
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 MYH9 4627
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
74 TRIM21 6737
Affinity Capture-MS Homo sapiens
75 SPR 6697
Reconstituted Complex Homo sapiens
76 KRT9 3857
Affinity Capture-MS Homo sapiens
77 GPSM3  
Affinity Capture-MS Homo sapiens
78 NOS2  
Affinity Capture-MS Homo sapiens
79 P4HB 5034
Co-fractionation Homo sapiens
80 ENO1 2023
Reconstituted Complex Homo sapiens
81 SNRPD1 6632
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
82 TGIF2LY  
Affinity Capture-MS Homo sapiens
83 HECTD1 25831
Affinity Capture-MS Homo sapiens
84 C19orf26 255057
Affinity Capture-MS Homo sapiens
85 CUL2 8453
Affinity Capture-MS Homo sapiens
86 LYST 1130
Two-hybrid Homo sapiens
87 CAPN1 823
Co-fractionation Homo sapiens
88 MTMR4  
Affinity Capture-MS Homo sapiens
89 MS4A1 931
Affinity Capture-MS Homo sapiens
90 PARD3 56288
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 ANLN 54443
Affinity Capture-MS Homo sapiens
92 EPB41L1 2036
Affinity Capture-MS Homo sapiens
93 ARHGAP32  
Affinity Capture-MS Homo sapiens
94 C2orf49 79074
Affinity Capture-MS Homo sapiens
95 MYL3 4634
Affinity Capture-MS Homo sapiens
96 HADHA 3030
Reconstituted Complex Homo sapiens
97 SDHA 6389
Affinity Capture-MS Homo sapiens
98 LMO7 4008
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
99 ANXA1 301
Reconstituted Complex Homo sapiens
100 FOXO1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
101 PRKCZ 5590
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
102 SRGAP2 23380
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 CUL3 8452
Affinity Capture-MS Homo sapiens
104 YWHAZ 7534
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
105 DCPS 28960
Reconstituted Complex Homo sapiens
106 WDR37 22884
Affinity Capture-MS Homo sapiens
107 FRMD5 84978
Affinity Capture-MS Homo sapiens
108 PIK3C2B 5287
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
109 FN1 2335
Affinity Capture-MS Homo sapiens
110 TXNDC9 10190
Co-fractionation Homo sapiens
111 THRA  
Reconstituted Complex Homo sapiens
112 TP53BP2  
Reconstituted Complex Homo sapiens
113 FAM122B  
Affinity Capture-MS Homo sapiens
114 SOAT1 6646
Affinity Capture-MS Homo sapiens
115 TJP2 9414
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
116 CRTC3  
Affinity Capture-MS Homo sapiens
117 RPA3 6119
Proximity Label-MS Homo sapiens
118 SIK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
119 GIGYF1  
Affinity Capture-MS Homo sapiens
120 WWC1  
Affinity Capture-MS Homo sapiens
121 DLST 1743
Affinity Capture-MS Homo sapiens
122 RAB11FIP2  
Affinity Capture-MS Homo sapiens
123 HSPA4 3308
Co-fractionation Homo sapiens
124 HIST1H1A 3024
Co-fractionation Homo sapiens
125 BANK1  
Affinity Capture-MS Homo sapiens
126 CDKN1B 1027
Affinity Capture-Western Homo sapiens
127 NFATC2  
Affinity Capture-MS Homo sapiens
128 GRIP1  
Affinity Capture-MS Homo sapiens
129 PRKDC 5591
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
130 SPIRE2  
Affinity Capture-MS Homo sapiens
131 CDC25A  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
132 GRK5 2869
Affinity Capture-MS Homo sapiens
133 FASN 2194
Reconstituted Complex Homo sapiens
134 RAE1 8480
Affinity Capture-MS Homo sapiens
135 RNASE2 6036
Reconstituted Complex Homo sapiens
136 PDE4B  
Protein-RNA Homo sapiens
137 GRB2 2885
Affinity Capture-MS Homo sapiens
138 BAD  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
139 SSFA2 6744
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
140 SSH1  
Affinity Capture-MS Homo sapiens
141 SHROOM1 134549
Affinity Capture-MS Homo sapiens
142 RUVBL2 10856
Reconstituted Complex Homo sapiens
143 FRYL 285527
Affinity Capture-MS Homo sapiens
144 LARS2 23395
Reconstituted Complex Homo sapiens
145 LRPPRC 10128
Co-fractionation Homo sapiens
146 ATAT1  
Affinity Capture-MS Homo sapiens
147 CDC37 11140
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
148 IRS2 8660
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
149 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
150 ARL8A 127829
Affinity Capture-MS Homo sapiens
151 SH3BP5L  
Affinity Capture-MS Homo sapiens
152 ZNRF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
153 BMPR1A 657
Affinity Capture-MS Homo sapiens
154 CCNK  
Affinity Capture-MS Homo sapiens
155 HSP90AA1 3320
Co-fractionation Homo sapiens
156 MEF2D  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
157 TUT1  
Affinity Capture-MS Homo sapiens
158 SSBP1 6742
Reconstituted Complex Homo sapiens
159 DYNC1H1 1778
Reconstituted Complex Homo sapiens
160 WWP2 11060
Affinity Capture-MS Homo sapiens
161 CLASP1 23332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
163 GAPDH 2597
Reconstituted Complex Homo sapiens
164 HNRNPL 3191
Co-fractionation Homo sapiens
165 EIF4B 1975
Co-fractionation Homo sapiens
166 MARK1 4139
Affinity Capture-MS Homo sapiens
167 GLCCI1 113263
Affinity Capture-MS Homo sapiens
168 PLEKHA7 144100
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 DES 1674
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
170 NRIP1 8204
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Phenotypic Suppression Homo sapiens
171 PRPF4 9128
Co-fractionation Homo sapiens
172 CUL7 9820
Affinity Capture-MS Homo sapiens
173 ADRM1 11047
Co-fractionation Homo sapiens
174 ANXA2 302
Reconstituted Complex Homo sapiens
175 DNMT1 1786
Reconstituted Complex Homo sapiens
176 FAM117B  
Affinity Capture-MS Homo sapiens
177 SRSF12  
Affinity Capture-MS Homo sapiens
178 FXYD1 5348
Reconstituted Complex Homo sapiens
179 GNAI3 2773
Co-fractionation Homo sapiens
180 WWC2  
Reconstituted Complex Homo sapiens
181 HNRNPH1 3187
Reconstituted Complex Homo sapiens
182 CCAR1 55749
Affinity Capture-Western Homo sapiens
183 SRGAP1 57522
Affinity Capture-MS Homo sapiens
184 LDHA 3939
Reconstituted Complex Homo sapiens
185 MCM3 4172
Reconstituted Complex Homo sapiens
186 CDK17 5128
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
187 LCK 3932
Affinity Capture-Western Homo sapiens
188 IARS2 55699
Reconstituted Complex Homo sapiens
189 CCSER2 54462
Affinity Capture-MS Homo sapiens
190 KLC2 64837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 VARS 7407
Reconstituted Complex Homo sapiens
192 TSC2 7249
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 TH  
Affinity Capture-MS Homo sapiens
194 MYLK2 85366
Affinity Capture-MS Homo sapiens
195 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
196 TPD52L1 7164
Affinity Capture-MS Homo sapiens
197 DAPK1 1612
Affinity Capture-Western Homo sapiens
198 BTF3 689
Affinity Capture-MS Homo sapiens
199 E2F1 1869
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
200 ALB 213
Affinity Capture-MS Homo sapiens
201 APC  
Reconstituted Complex Homo sapiens
202 ZNF638 27332
Affinity Capture-MS Homo sapiens
203 CBWD2  
Affinity Capture-MS Homo sapiens
204 HSP90AB1 3326
Co-fractionation Homo sapiens
205 FSHR  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
206 PLG 5340
Affinity Capture-MS Homo sapiens
207 KIF1B 23095
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 ARL8B 55207
Affinity Capture-MS Homo sapiens
209 ARHGEF16 27237
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
210 RPS3 6188
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
211 HDGF 3068
Co-fractionation Homo sapiens
212 WTAP 9589
Reconstituted Complex Homo sapiens
213 ARL6IP6  
Affinity Capture-MS Homo sapiens
214 PGK1 5230
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
215 TNK1  
Affinity Capture-MS Homo sapiens
216 REM1  
Far Western Homo sapiens
217 UCP3  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
218 TUBB 203068
Reconstituted Complex Homo sapiens
219 FAM53B  
Affinity Capture-MS Homo sapiens
220 CDK11B 984
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
221 NME7 29922
Reconstituted Complex Homo sapiens
222 TLN1 7094
Reconstituted Complex Homo sapiens
223 NPM1 4869
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
224 OBSL1 23363
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 RPLP2 6181
Reconstituted Complex Homo sapiens
226 RACGAP1 29127
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
227 FANCD2  
Affinity Capture-MS Homo sapiens
228 FAM117A 81558
Affinity Capture-MS Homo sapiens
229 HNRNPA1 3178
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
230 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
231 DDX6 1656
Affinity Capture-MS Homo sapiens
232 FGD6  
Affinity Capture-MS Homo sapiens
233 LATS1  
Affinity Capture-MS Homo sapiens
234 CTPS1 1503
Reconstituted Complex Homo sapiens
235 RFX7  
Affinity Capture-MS Homo sapiens
236 P3H4 10609
Affinity Capture-MS Homo sapiens
237 DENND2C  
Affinity Capture-MS Homo sapiens
238 Mad2l1bp  
Affinity Capture-MS Mus musculus
239 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
240 PTPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
241 AGAP1  
Affinity Capture-MS Homo sapiens
242 PFN1 5216
Reconstituted Complex Homo sapiens
243 CDCA7  
Affinity Capture-MS Homo sapiens
244 CAMK2A 815
Affinity Capture-Western Homo sapiens
245 VRK3 51231
Affinity Capture-MS Homo sapiens
246 PPP5C 5536
Affinity Capture-MS Homo sapiens
247 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
248 CABIN1  
Affinity Capture-Western Homo sapiens
249 FBLN1 2192
Two-hybrid Homo sapiens
250 SPEG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 CDKN1A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
252 TAOK1 57551
Affinity Capture-MS Homo sapiens
253 FGA 2243
Affinity Capture-MS Homo sapiens
254 RAI14 26064
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 CDR2L  
Affinity Capture-MS Homo sapiens
256 KLC4 89953
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
257 OPTN 10133
Affinity Capture-MS Homo sapiens
258 PABPC4 8761
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
259 RNF115  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
260 MPL 4352
Protein-peptide Homo sapiens
261 KIF5A 3798
Affinity Capture-MS Homo sapiens
262 TUBA1C 84790
Affinity Capture-MS Homo sapiens
263 NELFE 7936
Affinity Capture-MS Homo sapiens
264 CBL 867
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
265 SIPA1L2  
Affinity Capture-MS Homo sapiens
266 NCL 4691
Reconstituted Complex Homo sapiens
267 LUC7L2 51631
Affinity Capture-MS Homo sapiens
268 PKM 5315
Reconstituted Complex Homo sapiens
269 MAGOH 4116
Affinity Capture-MS Homo sapiens
270 RPLP0 6175
Reconstituted Complex Homo sapiens
271 GAREM  
Affinity Capture-MS Homo sapiens
272 Ksr1  
Affinity Capture-MS Mus musculus
273 CYLD  
Affinity Capture-MS Homo sapiens
274 Mlxipl  
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
275 NADK 65220
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
276 ALDH7A1 501
Co-fractionation Homo sapiens
277 PTOV1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 PSMA3 5684
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
279 HUS1  
Reconstituted Complex Homo sapiens
280 PANK2 80025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 ULK4  
Two-hybrid Homo sapiens
282 SMEK2  
Co-fractionation Homo sapiens
283 R3HDM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 REEP3 221035
Affinity Capture-MS Homo sapiens
285 MTX2 10651
Affinity Capture-MS Homo sapiens
286 UBE2L6 9246
Affinity Capture-MS Homo sapiens
287 DAB2IP 153090
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
288 RICTOR 253260
Affinity Capture-MS Homo sapiens
289 TUBB4B 10383
Affinity Capture-MS Homo sapiens
290 EGFR 1956
Two-hybrid Homo sapiens
PCA Homo sapiens
291 HOOK3 84376
Proximity Label-MS Homo sapiens
292 CDSN 1041
Affinity Capture-MS Homo sapiens
293 FUS 2521
Affinity Capture-MS Homo sapiens
294 KIAA0930  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 RIPK4  
Affinity Capture-MS Homo sapiens
296 WEE1 7465
Reconstituted Complex Homo sapiens
297 TRAPPC1 58485
Affinity Capture-MS Homo sapiens
298 G6PD 2539
Co-fractionation Homo sapiens
299 MAP3K1 4214
Affinity Capture-Western Homo sapiens
300 CDC25C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 PRKCQ 5588
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
302 TPM1 7168
Affinity Capture-MS Homo sapiens
303 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
304 BAG1 573
Affinity Capture-MS Homo sapiens
305 PTPDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 DDRGK1 65992
Affinity Capture-MS Homo sapiens
307 Yap1  
Affinity Capture-MS Mus musculus
308 PCM1 5108
Reconstituted Complex Homo sapiens
309 ALS2  
Affinity Capture-MS Homo sapiens
310 CCDC88A 55704
Affinity Capture-MS Homo sapiens
311 MPRIP 23164
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
312 DOCK11 139818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
314 SOD1 6647
Affinity Capture-MS Homo sapiens
315 FRMD6 122786
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 ZC3H13 23091
Reconstituted Complex Homo sapiens
317 RPL19 6143
Reconstituted Complex Homo sapiens
318 DENND4C 55667
Affinity Capture-MS Homo sapiens
319 MARK3 4140
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
320 MAP2K2 5605
Affinity Capture-MS Homo sapiens
321 KIF21B 23046
Affinity Capture-MS Homo sapiens
322 UHRF1BP1L 23074
Affinity Capture-MS Homo sapiens
323 SPOP  
Affinity Capture-MS Homo sapiens
324 SGK1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
325 SAMD4B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 ZFP36  
Affinity Capture-Western Homo sapiens
327 FAM163A  
Affinity Capture-MS Homo sapiens
328 SLK 9748
Co-fractionation Homo sapiens
329 HOMEZ  
Affinity Capture-MS Homo sapiens
330 SIPA1 6494
Affinity Capture-MS Homo sapiens
331 PACS2 23241
Affinity Capture-MS Homo sapiens
332 SH2D3A  
Affinity Capture-MS Homo sapiens
333 SPIRE1 56907
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 SIPA1L3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
335 FGB 2244
Affinity Capture-MS Homo sapiens
336 PSME3 10197
Reconstituted Complex Homo sapiens
337 CDK2 1017
Affinity Capture-MS Homo sapiens
338 RNF20 56254
Affinity Capture-MS Homo sapiens
339 MAT2B 27430
Co-fractionation Homo sapiens
340 MED1 5469
Reconstituted Complex Homo sapiens
341 KIF5C 3800
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 CEP250 11190
Affinity Capture-MS Homo sapiens
343 MAP2K1 5604
Affinity Capture-MS Homo sapiens
344 HNRNPK 3190
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
345 ESR1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
346 TFE3  
Affinity Capture-MS Homo sapiens
347 MCFD2 90411
Co-fractionation Homo sapiens
348 DDX39A 10212
Co-fractionation Homo sapiens
349 R3HDM2  
Affinity Capture-MS Homo sapiens
350 OSBPL3 26031
Affinity Capture-MS Homo sapiens
351 BCL2L1 598
Affinity Capture-MS Homo sapiens
352 CALML5 51806
Affinity Capture-MS Homo sapiens
353 DENND4A 10260
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 UACA 55075
Affinity Capture-MS Homo sapiens
355 SLC9A3R1 9368
Co-fractionation Homo sapiens
356 CLK2 1196
Affinity Capture-MS Homo sapiens
357 C1QBP 708
Co-fractionation Homo sapiens
358 KRAS 3845
Affinity Capture-MS Homo sapiens
359 ARHGAP23 57636
Affinity Capture-MS Homo sapiens
360 PSMD1 5707
Co-fractionation Homo sapiens
361 IRS4 8471
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
362 PRMT1 3276
Affinity Capture-MS Homo sapiens
363 MYL12B 103910
Affinity Capture-MS Homo sapiens
364 RALY 22913
Affinity Capture-MS Homo sapiens
365 PFKFB4 5210
Affinity Capture-MS Homo sapiens
366 MIS12  
Affinity Capture-MS Homo sapiens
367 MRPS27 23107
Reconstituted Complex Homo sapiens
368 HNRNPC 3183
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
369 DLG5 9231
Affinity Capture-MS Homo sapiens
370 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
371 Cul1 26965
Affinity Capture-MS Mus musculus
372 SPTB 6710
Reconstituted Complex Homo sapiens
373 SNRPE 6635
Reconstituted Complex Homo sapiens
374 ANKRD18A  
Affinity Capture-MS Homo sapiens
375 KSR1  
Affinity Capture-MS Homo sapiens
376 AKAP13 11214
Affinity Capture-MS Homo sapiens
377 DLD 1738
Affinity Capture-MS Homo sapiens
378 TPD52L2 7165
Affinity Capture-MS Homo sapiens
379 WASF2 10163
Affinity Capture-MS Homo sapiens
380 CBLL1  
Reconstituted Complex Homo sapiens
381 KRT17 3872
Affinity Capture-MS Homo sapiens
382 YWHAE 7531
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
383 MAP3K3 4215
Affinity Capture-MS Homo sapiens
384 IGHM 3507
Affinity Capture-MS Homo sapiens
385 ARL14EP  
Affinity Capture-MS Homo sapiens
386 CAMSAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
387 CBY1  
Affinity Capture-MS Homo sapiens
388 CRTC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
389 ANKS1A 23294
Affinity Capture-MS Homo sapiens
390 RPS6KB2  
Affinity Capture-MS Homo sapiens
391 FOXO6  
Affinity Capture-MS Homo sapiens
392 CAPZB 832
Affinity Capture-MS Homo sapiens
393 RPL10A 4736
Reconstituted Complex Homo sapiens
394 TRIM28 10155
Reconstituted Complex Homo sapiens
395 MLLT4 4301
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 PAK4 10298
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
397 PFKFB2 5208
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
398 MCM2 4171
Affinity Capture-MS Homo sapiens
399 RASAL2 9462
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
400 COPE 11316
Affinity Capture-MS Homo sapiens
401 SPAG9 9043
Co-fractionation Homo sapiens
402 PTPN4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
403 RPS10 6204
Co-fractionation Homo sapiens
404 IQGAP1 8826
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
405 FAM83G  
Affinity Capture-MS Homo sapiens
406 PHLDB2 90102
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
407 TFEB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
408 ZNF395 55893
Affinity Capture-MS Homo sapiens
409 PGD 5226
Co-fractionation Homo sapiens
410 TESK2  
Affinity Capture-MS Homo sapiens
411 TICRR 90381
Affinity Capture-MS Homo sapiens
412 ATG16L1 55054
Affinity Capture-MS Homo sapiens
413 TUBA1A 7846
Reconstituted Complex Homo sapiens
414 PFKFB3 5209
Affinity Capture-MS Homo sapiens
415 TFCP2 7024
Affinity Capture-MS Homo sapiens
416 UBQLN4 56893
Two-hybrid Homo sapiens
417 YAF2  
Affinity Capture-MS Homo sapiens
418 NIF3L1 60491
Affinity Capture-Western Homo sapiens
419 HIST2H4A 8370
Reconstituted Complex Homo sapiens
420 APPL1 26060
Affinity Capture-MS Homo sapiens
421 IGLC7 28834
Affinity Capture-MS Homo sapiens
422 HSPA8 3312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 MELK  
Affinity Capture-MS Homo sapiens
424 NCOA1  
Reconstituted Complex Homo sapiens
425 MTNR1B  
Reconstituted Complex Homo sapiens
426 UBE2V1 7335
Co-fractionation Homo sapiens
427 VTN 7448
Affinity Capture-MS Homo sapiens
428 EPB41L3 23136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
429 AMOTL2 51421
Affinity Capture-MS Homo sapiens
430 BCAR1 9564
Affinity Capture-MS Homo sapiens
431 ATP5A1 498
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
432 LMNA 4000
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
433 REEP4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 PARK2  
Affinity Capture-MS Homo sapiens
435 IGF1R 3480
Affinity Capture-MS Homo sapiens
436 PNKP 11284
Affinity Capture-MS Homo sapiens
437 EXO1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
438 RABEP1 9135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
439 SAMD4A 23034
Affinity Capture-MS Homo sapiens
440 TRIM42  
Two-hybrid Homo sapiens
441 SPARC 6678
Co-fractionation Homo sapiens
442 WDR61 80349
Reconstituted Complex Homo sapiens
443 USP8 9101
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
444 HIST1H1D 3007
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
445 MAPT  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
446 C5orf30  
Affinity Capture-MS Homo sapiens
447 CHMP4B 128866
Affinity Capture-MS Homo sapiens
448 ZHX2  
Reconstituted Complex Homo sapiens
449 CEP170 9859
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
450 UBFD1 56061
Co-fractionation Homo sapiens
451 NTRK1 4914
Affinity Capture-MS Homo sapiens
452 TPI1 7167
Reconstituted Complex Homo sapiens
453 LRBA 987
Co-fractionation Homo sapiens
454 ADRB2  
Two-hybrid Homo sapiens
455 ACTB 60
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
456 DHX9 1660
Reconstituted Complex Homo sapiens
457 PDE7B  
Affinity Capture-MS Homo sapiens
458 ACTA2 59
Affinity Capture-MS Homo sapiens
459 FGG 2266
Affinity Capture-MS Homo sapiens
460 HDAC5 10014
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
461 MFF 56947
Affinity Capture-MS Homo sapiens
462 DNM1L 10059
Affinity Capture-MS Homo sapiens
463 RMDN3 55177
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
464 MYH2  
Affinity Capture-MS Homo sapiens
465 LARP1 23367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
466 PANK1  
Reconstituted Complex Homo sapiens
467 TTN 7273
Affinity Capture-MS Homo sapiens
468 DISC1 27185
Two-hybrid Homo sapiens
469 ZBTB2 57621
Affinity Capture-MS Homo sapiens
470 ZAK 51776
Affinity Capture-MS Homo sapiens
471 USP42  
Affinity Capture-MS Homo sapiens
472 AHCY 191
Reconstituted Complex Homo sapiens
473 SIK3 23387
Affinity Capture-MS Homo sapiens
474 KMT2A  
Cross-Linking-MS (XL-MS) Homo sapiens
475 METTL14  
Affinity Capture-MS Homo sapiens
476 KRT18 3875
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
477 SHROOM3 57619
Affinity Capture-MS Homo sapiens
478 UNC79 57578
Affinity Capture-MS Homo sapiens
479 EEF2 1938
Co-fractionation Homo sapiens
480 OSBPL6  
Affinity Capture-MS Homo sapiens
481 EPPK1 83481
Affinity Capture-MS Homo sapiens
482 UCP2  
Two-hybrid Homo sapiens
483 RPL21 6144
Affinity Capture-MS Homo sapiens
484 PRKD1 5587
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
485 H1F0 3005
Affinity Capture-MS Homo sapiens
486 FBXO6 26270
Affinity Capture-MS Homo sapiens
487 PDPK1 5170
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
488 MDM4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
489 DMTN  
Affinity Capture-MS Homo sapiens
490 RFC1 5981
Reconstituted Complex Homo sapiens
491 PDCD4 27250
Co-fractionation Homo sapiens
492 NRBP1 29959
Co-fractionation Homo sapiens
493 SMAD9  
Two-hybrid Homo sapiens
494 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
495 MTOR 2475
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
496 CGN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
497 RAF1 5894
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
498 RANBP1 5902
Cross-Linking-MS (XL-MS) Homo sapiens
499 CLPB 81570
Co-fractionation Homo sapiens
500 TXNDC5 81567
Co-fractionation Homo sapiens
501 SIK2  
Affinity Capture-Western Homo sapiens
502 ARAF 369
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
503 NEDD4L 23327
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
504 SMS 6611
Co-fractionation Homo sapiens
505 CBX4  
Affinity Capture-MS Homo sapiens
506 TUBB2A 7280
Affinity Capture-MS Homo sapiens
507 CACNA1S 779
Affinity Capture-MS Homo sapiens
508 MYCBP 26292
Affinity Capture-MS Homo sapiens
509 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
510 FOXO3  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
511 VASH2  
Affinity Capture-MS Homo sapiens
512 SHCBP1 79801
Affinity Capture-MS Homo sapiens
513 ILF3 3609
Co-fractionation Homo sapiens
514 NKD2 85409
Affinity Capture-MS Homo sapiens
515 NMI  
Co-fractionation Homo sapiens
516 LSR 51599
Affinity Capture-MS Homo sapiens
517 DDX3X 1654
Reconstituted Complex Homo sapiens
518 EIF4G1 1981
Co-fractionation Homo sapiens
519 RPTOR 57521
Affinity Capture-Western Homo sapiens
520 ADCK2  
Affinity Capture-MS Homo sapiens
521 EFNB1 1947
Two-hybrid Homo sapiens
522 ABL1 25
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
523 HSPB1 3315
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
524 Shoc2  
Affinity Capture-MS Mus musculus
525 EDC3 80153
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
526 GAB2 9846
Affinity Capture-MS Homo sapiens
527 ACSL4 2182
Reconstituted Complex Homo sapiens
528 PPFIBP2 8495
Affinity Capture-MS Homo sapiens
529 UFL1 23376
Affinity Capture-MS Homo sapiens
530 ACTG1 71
Affinity Capture-MS Homo sapiens
531 ZNRF2 223082
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
532 API5 8539
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
533 AARS2  
Reconstituted Complex Homo sapiens
534 LRRK2 120892
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
535 NDE1 54820
Reconstituted Complex Homo sapiens
536 F2 2147
Affinity Capture-MS Homo sapiens
537 HNRNPF 3185
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
538 SERBP1 26135
Affinity Capture-MS Homo sapiens
539 AR 367
Reconstituted Complex Homo sapiens
540 RC3H1 149041
Affinity Capture-MS Homo sapiens
541 COPS4 51138
Reconstituted Complex Homo sapiens
542 VIM 7431
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
543 EML3 256364
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
544 ABLIM1 3983
Affinity Capture-MS Homo sapiens
545 EIF5 1983
Co-fractionation Homo sapiens
546 SH3PXD2A 9644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
547 UBE2H 7328
Affinity Capture-MS Homo sapiens
548 SLFN11 91607
Proximity Label-MS Homo sapiens
549 TNFAIP3 7128
Two-hybrid Homo sapiens
550 ACTR2 10097
Affinity Capture-MS Homo sapiens
551 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
552 SLC4A7 9497
Affinity Capture-MS Homo sapiens
553 CRTC2 200186
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
554 CEP95  
Affinity Capture-MS Homo sapiens
555 Sgol2  
Affinity Capture-MS Mus musculus
556 RNASEH2B  
Affinity Capture-MS Homo sapiens
557 NOLC1 9221
Reconstituted Complex Homo sapiens
558 CEP89 84902
Affinity Capture-MS Homo sapiens
559 VAPA 9218
Affinity Capture-MS Homo sapiens
560 WWP1 11059
Reconstituted Complex Homo sapiens
561 IGHG1 3500
Affinity Capture-MS Homo sapiens
562 PSMD11 5717
Co-fractionation Homo sapiens
563 SPATA13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
564 RPL15 6138
Reconstituted Complex Homo sapiens
565 SASH1 23328
Affinity Capture-MS Homo sapiens
566 CALM1 801
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
567 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
568 CFL1 1072
Reconstituted Complex Homo sapiens
569 PRR5  
Affinity Capture-MS Homo sapiens
570 TMPO 7112
Affinity Capture-MS Homo sapiens
571 GSK3A 2931
Affinity Capture-MS Homo sapiens
572 KIAA1429 25962
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
573 RNH1 6050
Co-fractionation Homo sapiens
574 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
575 FBXW7  
Affinity Capture-MS Homo sapiens
576 MARK2 2011
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
577 C21orf2  
Affinity Capture-MS Homo sapiens
578 PDXK 8566
Reconstituted Complex Homo sapiens
579 PLEKHG5 57449
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
580 TGFB1 7040
Affinity Capture-MS Homo sapiens
581 SPECC1L 23384
Affinity Capture-MS Homo sapiens
582 PCK1 5105
Affinity Capture-MS Homo sapiens
583 WDR20 91833
Affinity Capture-MS Homo sapiens
584 EPN2 22905
Affinity Capture-MS Homo sapiens
585 KIF5B 3799
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
586 PLK4  
Affinity Capture-MS Homo sapiens
587 CEP112  
Affinity Capture-MS Homo sapiens
588 HBB 3043
Affinity Capture-MS Homo sapiens
589 SLC27A2 11001
Reconstituted Complex Homo sapiens
590 FBXW8 26259
Affinity Capture-MS Homo sapiens
591 YWHAG 7532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
592 TIAM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
593 AGTR1  
Two-hybrid Homo sapiens
594 MYCBP2 23077
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
595 WNK4  
Affinity Capture-MS Homo sapiens
596 TERT  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
597 CDC73  
Affinity Capture-MS Homo sapiens
598 SERPINA1 5265
Affinity Capture-MS Homo sapiens
599 ARL1 400
Affinity Capture-MS Homo sapiens
600 MYCN  
Affinity Capture-MS Homo sapiens
601 TRAPPC11 60684
Affinity Capture-MS Homo sapiens
602 ADSS 159
Affinity Capture-MS Homo sapiens
603 MYH13 8735
Affinity Capture-MS Homo sapiens
604 KIAA1804  
Affinity Capture-MS Homo sapiens
605 TRIP12 9320
Co-fractionation Homo sapiens
606 VPS13D 55187
Affinity Capture-MS Homo sapiens
607 HMGCS2 3158
Affinity Capture-MS Homo sapiens
608 KLC3  
Affinity Capture-MS Homo sapiens
609 KRT8 3856
Affinity Capture-MS Homo sapiens
610 CDK16 5127
Two-hybrid Homo sapiens
611 ARL2BP 23568
Affinity Capture-MS Homo sapiens
612 TGM2 7052
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
613 CCAR2 57805
Co-fractionation Homo sapiens
614 STAU1 6780
Affinity Capture-MS Homo sapiens
615 CPS1 1373
Affinity Capture-MS Homo sapiens
616 SRSF6 6431
Affinity Capture-MS Homo sapiens
617 TPD52 7163
Affinity Capture-MS Homo sapiens
618 PFDN2 5202
Co-fractionation Homo sapiens
619 VCL 7414
Co-fractionation Homo sapiens
620 VCP 7415
Affinity Capture-MS Homo sapiens
621 PLEKHM3 389072
Affinity Capture-MS Homo sapiens
622 DTL  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
623 IFI16 3428
Affinity Capture-MS Homo sapiens
624 PI4KB 5298
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
625 TRIM32 22954
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
626 CAMKK1  
Affinity Capture-MS Homo sapiens
627 CRY2  
Affinity Capture-MS Homo sapiens
628 DDX1 1653
Reconstituted Complex Homo sapiens
629 PABPN1 8106
Reconstituted Complex Homo sapiens
630 MYH11 4629
Affinity Capture-MS Homo sapiens
631 BRAF  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
632 ZBTB21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
633 PHACTR4 65979
Affinity Capture-MS Homo sapiens
634 UPF1 5976
Affinity Capture-MS Homo sapiens
635 TSC1 7248
Affinity Capture-MS Homo sapiens
636 ATP5B 506
Affinity Capture-MS Homo sapiens
637 SSX2IP  
Two-hybrid Homo sapiens
638 TUBA3C 7278
Affinity Capture-MS Homo sapiens
639 BAG3 9531
Affinity Capture-MS Homo sapiens
640 CAD 790
Co-fractionation Homo sapiens
641 LIMA1 51474
Reconstituted Complex Homo sapiens
642 NUMA1 4926
Reconstituted Complex Homo sapiens
643 BCAP31 10134
Reconstituted Complex Homo sapiens
644 BAX 581
Affinity Capture-Western Homo sapiens
Dosage Rescue Homo sapiens
Reconstituted Complex Homo sapiens
645 VAPB 9217
Affinity Capture-MS Homo sapiens
646 WWTR1 25937
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
647 CLK3  
Affinity Capture-MS Homo sapiens
648 OTUD1 220213
Affinity Capture-MS Homo sapiens
649 HIST2H3C 126961
Affinity Capture-Western Homo sapiens
650 PINK1  
Affinity Capture-MS Homo sapiens
651 NCKAP1 10787
Affinity Capture-MS Homo sapiens
652 CAMSAP3  
Affinity Capture-MS Homo sapiens
653 CTNNB1 1499
Affinity Capture-MS Homo sapiens
654 SRSF1 6426
Affinity Capture-MS Homo sapiens
655 PRDX1 5052
Reconstituted Complex Homo sapiens
656 RNF138  
Affinity Capture-MS Homo sapiens
657 RPL7 6129
Reconstituted Complex Homo sapiens
658 ECHS1 1892
Co-fractionation Homo sapiens
659 TBCD 6904
Co-fractionation Homo sapiens
660 SIPA1L1 26037
Affinity Capture-MS Homo sapiens
661 HIST1H2BG 8339
Reconstituted Complex Homo sapiens
662 AKT1S1 84335
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
663 LMNB1 4001
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
664 HIBADH 11112
Co-fractionation Homo sapiens
665 NFKB1 4790
Two-hybrid Homo sapiens
666 PPFIBP1 8496
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
667 BAZ1A 11177
Affinity Capture-MS Homo sapiens
668 SRSF10 10772
Affinity Capture-MS Homo sapiens
669 CLTC 1213
Reconstituted Complex Homo sapiens
670 FSCN1 6624
Reconstituted Complex Homo sapiens
671 PPFIA1 8500
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
672 CCDC125 202243
Two-hybrid Homo sapiens
673 BAIAP2 10458
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
674 PDE3A  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
675 MDM2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens