Gene description for PRKD1
Gene name	protein kinase D1
Gene symbol	PRKD1
Other names/aliases	PKC-MU PKCM PKD PRKCM
Species	Homo sapiens
Database cross references - PRKD1
ExoCarta	ExoCarta_5587
Entrez Gene	5587
HGNC	9407
MIM	605435
UniProt	Q15139
PRKD1 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells	25844599

Gene ontology annotations for PRKD1

Molecular Function     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IPI     protein serine/threonine kinase activity GO:0004674 TAS     metal ion binding GO:0046872 IEA     protein kinase C activity GO:0004697 IDA     ATP binding GO:0005524 IEA Biological Process     positive regulation of peptidyl-serine phosphorylation GO:0033138 IGI     regulation of keratinocyte proliferation GO:0010837 ISS     intracellular signal transduction GO:0035556 IMP     positive regulation of blood vessel endothelial cell migration GO:0043536 IMP     regulation of integrin-mediated signaling pathway GO:2001044 TAS     angiogenesis GO:0001525 IEA     protein kinase D signaling GO:0089700 IGI     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP     small molecule metabolic process GO:0044281 TAS     peptidyl-serine phosphorylation GO:0018105 IDA     integrin-mediated signaling pathway GO:0007229 TAS     cellular response to oxidative stress GO:0034599 IDA     positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 IMP     positive regulation of endothelial cell migration GO:0010595 IMP     signal transduction GO:0007165 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     cell proliferation GO:0008283 TAS     positive regulation of angiogenesis GO:0045766 IMP     sphingolipid biosynthetic process GO:0030148 TAS     Golgi organization GO:0007030 IMP     sphingolipid metabolic process GO:0006665 TAS     innate immune response GO:0045087 IEA     vascular endothelial growth factor receptor signaling pathway GO:0048010 IMP     positive regulation of histone deacetylase activity GO:1901727 IGI     cellular response to vascular endothelial growth factor stimulus GO:0035924 IMP     Golgi vesicle transport GO:0048193 ISS     positive regulation of CREB transcription factor activity GO:0032793 IGI     protein autophosphorylation GO:0046777 TAS     positive regulation of neuron projection development GO:0010976 IMP     positive regulation of endothelial cell proliferation GO:0001938 IGI     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP     negative regulation of cell death GO:0060548 IMP     apoptotic process GO:0006915 IEA     negative regulation of endocytosis GO:0045806 TAS     positive regulation of endothelial cell chemotaxis GO:2001028 IMP     inflammatory response GO:0006954 IEA     positive regulation of osteoblast differentiation GO:0045669 ISS Subcellular Localization     cytosol GO:0005829 TAS     cell cortex GO:0005938 IEA     trans-Golgi network GO:0005802 IDA     cell-cell junction GO:0005911 IEA     Golgi apparatus GO:0005794 IDA     cytoplasm GO:0005737 IDA     nucleus GO:0005634 IEA     plasma membrane GO:0005886 IDA     integral component of plasma membrane GO:0005887 TAS