Gene description for PRKD2
Gene name	protein kinase D2
Gene symbol	PRKD2
Other names/aliases	HSPC187 PKD2 nPKC-D2
Species	Homo sapiens
Database cross references - PRKD2
ExoCarta	ExoCarta_25865
Vesiclepedia	VP_25865
Entrez Gene	25865
HGNC	17293
MIM	607074
UniProt	Q9BZL6
PRKD2 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for PRKD2

Molecular Function     protein kinase activity GO:0004672 IDA     protein serine/threonine kinase activity GO:0004674 IBA     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 IMP     protein serine/threonine kinase activity GO:0004674 NAS     diacylglycerol-dependent serine/threonine kinase activity GO:0004697 TAS     calcium,diacylglycerol-dependent serine/threonine kinase activity GO:0004698 IEA     diacylglycerol-dependent, calcium-independent serine/threonine kinase activity GO:0004699 IEA     protein kinase C binding GO:0005080 IPI     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     metal ion binding GO:0046872 IEA     protein serine kinase activity GO:0106310 IGI Biological Process     angiogenesis GO:0001525 IEA     positive regulation of endothelial cell proliferation GO:0001938 IGI     positive regulation of endothelial cell proliferation GO:0001938 IMP     adaptive immune response GO:0002250 IEA     protein phosphorylation GO:0006468 IDA     protein phosphorylation GO:0006468 NAS     cell adhesion GO:0007155 IEA     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IBA     positive regulation of endothelial cell migration GO:0010595 IMP     peptidyl-serine phosphorylation GO:0018105 IMP     peptidyl-threonine phosphorylation GO:0018107 IMP     sphingolipid biosynthetic process GO:0030148 TAS     positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 IMP     positive regulation of interleukin-2 production GO:0032743 ISS     positive regulation of interleukin-8 production GO:0032757 IMP     intracellular signal transduction GO:0035556 IBA     intracellular signal transduction GO:0035556 IMP     cellular response to vascular endothelial growth factor stimulus GO:0035924 IGI     cellular response to vascular endothelial growth factor stimulus GO:0035924 IMP     positive regulation of blood vessel endothelial cell migration GO:0043536 IGI     positive regulation of blood vessel endothelial cell migration GO:0043536 IMP     positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 IMP     positive regulation of angiogenesis GO:0045766 IGI     positive regulation of angiogenesis GO:0045766 IMP     positive regulation of cell adhesion GO:0045785 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IGI     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     protein autophosphorylation GO:0046777 IDA     protein autophosphorylation GO:0046777 TAS     vascular endothelial growth factor receptor signaling pathway GO:0048010 IGI     vascular endothelial growth factor receptor signaling pathway GO:0048010 IMP     T cell receptor signaling pathway GO:0050852 IDA     positive regulation of T cell receptor signaling pathway GO:0050862 ISS     positive regulation of DNA-binding transcription factor activity GO:0051091 IMP     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     endothelial tube morphogenesis GO:0061154 TAS     regulation of T cell apoptotic process GO:0070232 IMP     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     positive regulation of DNA biosynthetic process GO:2000573 ISS     positive regulation of endothelial cell chemotaxis GO:2001028 IGI     positive regulation of endothelial cell chemotaxis GO:2001028 IMP Subcellular Localization     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IDA     Golgi apparatus GO:0005794 IEA     cytosol GO:0005829 IBA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IEA