Gene description for CASK
Gene name	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Gene symbol	CASK
Other names/aliases	CAGH39 CAMGUK CMG FGS4 LIN2 MICPCH MRXSNA TNRC8
Species	Homo sapiens
Database cross references - CASK
ExoCarta	ExoCarta_8573
Entrez Gene	8573
HGNC	1497
MIM	300172
UniProt	O14936
CASK identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for CASK

Molecular Function     protein serine/threonine kinase activity GO:0004674 IEA     neurexin family protein binding GO:0042043 IEA     ATP binding GO:0005524 IEA     guanylate kinase activity GO:0004385 TAS     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IEA Biological Process     extracellular matrix organization GO:0030198 TAS     negative regulation of cellular response to growth factor stimulus GO:0090288 IMP     positive regulation of calcium ion import GO:0090280 IEA     nucleotide phosphorylation GO:0046939 TAS     calcium ion import GO:0070509 IEA     neurotransmitter secretion GO:0007269 TAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     negative regulation of cell-matrix adhesion GO:0001953 IMP     protein phosphorylation GO:0006468 IEA     negative regulation of wound healing GO:0061045 IMP     synaptic transmission GO:0007268 TAS     cell adhesion GO:0007155 TAS     negative regulation of keratinocyte proliferation GO:0010839 IMP Subcellular Localization     basement membrane GO:0005604 IDA     cytoplasm GO:0005737 IDA     nuclear matrix GO:0016363 IDA     cell-cell junction GO:0005911 IDA     nuclear lamina GO:0005652 IDA     presynaptic membrane GO:0042734 ISS     focal adhesion GO:0005925 IDA     ciliary membrane GO:0060170 ISS     plasma membrane GO:0005886 TAS     nucleolus GO:0005730 IDA     basolateral plasma membrane GO:0016323 IEA     cytosol GO:0005829 TAS     actin cytoskeleton GO:0015629 TAS