Gene description for FAM133A
Gene name family with sequence similarity 133, member A
Gene symbol FAM133A
Other names/aliases CT115
Species Homo sapiens
 Database cross references - FAM133A
ExoCarta ExoCarta_286499
Vesiclepedia VP_286499
Entrez Gene 286499
HGNC 26748
UniProt Q8N9E0  
 FAM133A identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for FAM133A
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified FAM133A in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for FAM133A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CT45A1  
Two-hybrid Homo sapiens
2 DBT 1629
Affinity Capture-MS Homo sapiens
3 PBK  
Affinity Capture-MS Homo sapiens
4 FAM133B 257415
Affinity Capture-MS Homo sapiens
5 TP53 7157
Affinity Capture-MS Homo sapiens
6 UBE3A 7337
Affinity Capture-MS Homo sapiens
7 PRR13  
Two-hybrid Homo sapiens
8 ATPIF1 93974
Affinity Capture-MS Homo sapiens
9 RNF151  
Two-hybrid Homo sapiens
10 TRAF2 7186
Affinity Capture-MS Homo sapiens
11 GFER  
Affinity Capture-MS Homo sapiens
12 WRAP73 49856
Affinity Capture-MS Homo sapiens
13 C11orf57  
Two-hybrid Homo sapiens
14 PRKCA 5578
Affinity Capture-MS Homo sapiens
15 APPL1 26060
Affinity Capture-MS Homo sapiens
16 FOLR1 2348
Affinity Capture-MS Homo sapiens
17 SDCBP2 27111
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 KCTD9  
Affinity Capture-MS Homo sapiens
19 CASK 8573
Affinity Capture-MS Homo sapiens
20 STAC3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
21 DNM1L 10059
Affinity Capture-MS Homo sapiens
22 PNN 5411
Affinity Capture-MS Homo sapiens
23 NOS1AP  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
24 ADSL 158
Affinity Capture-MS Homo sapiens
25 JMJD6 23210
Affinity Capture-MS Homo sapiens
26 PRCP 5547
Affinity Capture-MS Homo sapiens
27 TJP1 7082
Affinity Capture-MS Homo sapiens
28 MAPK3 5595
Affinity Capture-MS Homo sapiens
29 DIS3 22894
Affinity Capture-MS Homo sapiens
30 SLC9A3R2 9351
Affinity Capture-MS Homo sapiens
31 HIST1H2BN 8341
Two-hybrid Homo sapiens
32 C1orf226  
Affinity Capture-MS Homo sapiens
33 C1orf35  
Two-hybrid Homo sapiens
34 CSNK2A1 1457
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
35 RFX1  
Affinity Capture-MS Homo sapiens
36 DHPS 1725
Affinity Capture-MS Homo sapiens
37 AGPAT3 56894
Two-hybrid Homo sapiens
38 IMPACT 55364
Affinity Capture-MS Homo sapiens
39 PRPF40A 55660
Affinity Capture-MS Homo sapiens
40 FAM120B 84498
Affinity Capture-MS Homo sapiens
41 SMEK1 55671
Affinity Capture-MS Homo sapiens
42 MAPK1 5594
Affinity Capture-MS Homo sapiens
43 CSNK2B 1460
Affinity Capture-MS Homo sapiens
44 THAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
45 NT5C2 22978
Affinity Capture-MS Homo sapiens
46 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
47 ACOX3 8310
Affinity Capture-MS Homo sapiens
48 KCTD10 83892
Affinity Capture-MS Homo sapiens
49 RFX2  
Affinity Capture-MS Homo sapiens
50 ACTR3B 57180
Affinity Capture-MS Homo sapiens
51 PPIL4  
Affinity Capture-MS Homo sapiens
52 EIF3J 8669
Affinity Capture-MS Homo sapiens
53 CEP70  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
54 TRIM23 373
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
55 AFF4 27125
Affinity Capture-MS Homo sapiens
56 CCNL1  
Two-hybrid Homo sapiens
57 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
58 C20orf27 54976
Affinity Capture-MS Homo sapiens
59 HSDL2 84263
Affinity Capture-MS Homo sapiens
60 CMTR1 23070
Affinity Capture-MS Homo sapiens
61 DNPEP 23549
Affinity Capture-MS Homo sapiens
62 BEND7 222389
Two-hybrid Homo sapiens
63 PPP2CA 5515
Affinity Capture-MS Homo sapiens
64 RBMX2  
Two-hybrid Homo sapiens
65 NAA35 60560
Affinity Capture-MS Homo sapiens
66 USP7 7874
Affinity Capture-MS Homo sapiens
67 TPP2 7174
Affinity Capture-MS Homo sapiens
68 SPECC1L 23384
Affinity Capture-MS Homo sapiens
69 HECTD1 25831
Affinity Capture-MS Homo sapiens
70 LMNA 4000
Cross-Linking-MS (XL-MS) Homo sapiens
71 H2AFY 9555
Two-hybrid Homo sapiens
72 DBN1 1627
Affinity Capture-MS Homo sapiens
73 LANCL2 55915
Affinity Capture-MS Homo sapiens
74 MMAB 326625
Affinity Capture-MS Homo sapiens
75 HDDC3  
Affinity Capture-MS Homo sapiens
76 HBS1L 10767
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM133A is involved
No pathways found





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