Gene description for FAM133B
Gene name family with sequence similarity 133, member B
Gene symbol FAM133B
Other names/aliases -
Species Homo sapiens
 Database cross references - FAM133B
ExoCarta ExoCarta_257415
Vesiclepedia VP_257415
Entrez Gene 257415
HGNC 28629
UniProt Q5BKY9  
 FAM133B identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for FAM133B
Molecular Function
    RNA binding GO:0003723 HDA
 Experiment description of studies that identified FAM133B in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for FAM133B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 ATG16L1 55054
Affinity Capture-MS Homo sapiens
3 ATR  
Affinity Capture-MS Homo sapiens
4 UBE2H 7328
Affinity Capture-MS Homo sapiens
5 MYCN  
Affinity Capture-MS Homo sapiens
6 S100P 6286
Affinity Capture-MS Homo sapiens
7 PPP4R2  
Affinity Capture-MS Homo sapiens
8 TP53 7157
Affinity Capture-MS Homo sapiens
9 C6orf201  
Affinity Capture-MS Homo sapiens
10 DDX58 23586
Affinity Capture-RNA Homo sapiens
11 APP 351
Reconstituted Complex Homo sapiens
12 C20orf197  
Affinity Capture-MS Homo sapiens
13 CDK2 1017
Affinity Capture-MS Homo sapiens
14 MYC  
Affinity Capture-MS Homo sapiens
15 YAP1 10413
Affinity Capture-MS Homo sapiens
16 TSNAX 7257
Affinity Capture-MS Homo sapiens
17 RAD18  
Affinity Capture-MS Homo sapiens
18 HECTD1 25831
Affinity Capture-MS Homo sapiens
19 LMNA 4000
Cross-Linking-MS (XL-MS) Homo sapiens
20 HECW2  
Affinity Capture-MS Homo sapiens
21 PEA15 8682
Affinity Capture-MS Homo sapiens
22 FAM133A 286499
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM133B is involved
No pathways found





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