Gene description for DBN1
Gene name drebrin 1
Gene symbol DBN1
Other names/aliases D0S117E
Species Homo sapiens
 Database cross references - DBN1
ExoCarta ExoCarta_1627
Vesiclepedia VP_1627
Entrez Gene 1627
HGNC 2695
MIM 126660
UniProt Q16643  
 DBN1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for DBN1
Molecular Function
    actin binding GO:0003779 NAS
    protein binding GO:0005515 IPI
    profilin binding GO:0005522 ISS
    cadherin binding GO:0045296 HDA
Biological Process
    in utero embryonic development GO:0001701 IEA
    actin filament organization GO:0007015 ISS
    cell communication by chemical coupling GO:0010643 IEA
    cell communication by electrical coupling GO:0010644 IEA
    positive regulation of synaptic plasticity GO:0031915 ISS
    maintenance of protein location in cell GO:0032507 IEA
    regulation of neuronal synaptic plasticity GO:0048168 NAS
    generation of neurons GO:0048699 IEA
    regulation of dendrite development GO:0050773 NAS
    cytoplasmic sequestering of protein GO:0051220 IBA
    cytoplasmic sequestering of protein GO:0051220 IDA
    positive regulation of dendritic spine morphogenesis GO:0061003 ISS
    neural precursor cell proliferation GO:0061351 IEA
    positive regulation of receptor localization to synapse GO:1902685 ISS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    cytoskeleton GO:0005856 IBA
    cytoskeleton GO:0005856 IDA
    gap junction GO:0005921 IEA
    postsynaptic density GO:0014069 IEA
    actin cytoskeleton GO:0015629 ISS
    dendrite GO:0030425 IDA
    dendrite GO:0030425 NAS
    growth cone GO:0030426 ISS
    cortical cytoskeleton GO:0030863 TAS
    actomyosin GO:0042641 NAS
    postsynaptic membrane GO:0045211 IEA
    glutamatergic synapse GO:0098978 IEA
    postsynaptic cytosol GO:0099524 IEA
 Experiment description of studies that identified DBN1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
21
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DBN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 ABCG2 9429
Affinity Capture-MS Homo sapiens
3 ARPC5 10092
Affinity Capture-MS Homo sapiens
4 ACTR2 10097
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 HOMER3 9454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 GOLGA6A  
Cross-Linking-MS (XL-MS) Homo sapiens
7 ABLIM1 3983
Affinity Capture-MS Homo sapiens
8 GOLGA6C  
Cross-Linking-MS (XL-MS) Homo sapiens
9 DCTN2 10540
Affinity Capture-MS Homo sapiens
10 PPP1CB 5500
Affinity Capture-MS Homo sapiens
11 Tpm1 22003
Affinity Capture-MS Mus musculus
12 GART 2618
Affinity Capture-MS Homo sapiens
13 POT1  
Two-hybrid Homo sapiens
14 SEC16A 9919
Affinity Capture-MS Homo sapiens
15 MARCKS 4082
Co-fractionation Homo sapiens
16 PDAP1 11333
Cross-Linking-MS (XL-MS) Homo sapiens
17 ARPC2 10109
Affinity Capture-MS Homo sapiens
18 KCTD10 83892
Affinity Capture-MS Homo sapiens
19 RRAS2 22800
Affinity Capture-MS Homo sapiens
20 DYNC1I2 1781
Cross-Linking-MS (XL-MS) Homo sapiens
21 SP1  
Affinity Capture-MS Homo sapiens
22 CARD10  
Affinity Capture-MS Homo sapiens
23 FBXO25  
Affinity Capture-MS Homo sapiens
24 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
25 GAK 2580
Affinity Capture-MS Homo sapiens
26 STON2 85439
Affinity Capture-MS Homo sapiens
27 DYNC1I1  
Cross-Linking-MS (XL-MS) Homo sapiens
28 KIF20A 10112
Affinity Capture-MS Homo sapiens
29 TAB1 10454
Two-hybrid Homo sapiens
30 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
31 ZC3H4 23211
Co-fractionation Homo sapiens
32 CALM1 801
Affinity Capture-MS Homo sapiens
33 Actb 11461
Affinity Capture-MS Mus musculus
34 CLTB 1212
Affinity Capture-MS Homo sapiens
35 PARK7 11315
Affinity Capture-MS Homo sapiens
36 SOX2  
Affinity Capture-MS Homo sapiens
37 PPP1CC 5501
Affinity Capture-MS Homo sapiens
38 MAP1LC3B 81631
Two-hybrid Homo sapiens
39 CAPZB 832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 PPP1R12A 4659
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
41 WDR76  
Affinity Capture-MS Homo sapiens
42 DCTN5 84516
Affinity Capture-MS Homo sapiens
43 ZDHHC5 25921
Affinity Capture-MS Homo sapiens
44 PPP1R3C  
Affinity Capture-MS Homo sapiens
45 KIF23 9493
Affinity Capture-MS Homo sapiens
46 MYO5B 4645
Affinity Capture-MS Homo sapiens
47 ACTR3 10096
Affinity Capture-MS Homo sapiens
48 AP2A1 160
Affinity Capture-MS Homo sapiens
49 CALD1 800
Affinity Capture-MS Homo sapiens
50 CDH2 1000
Co-fractionation Homo sapiens
51 YES1 7525
Affinity Capture-MS Homo sapiens
52 PRC1 9055
Affinity Capture-MS Homo sapiens
53 NUDT3 11165
Two-hybrid Homo sapiens
54 IQGAP1 8826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 KLF6  
Affinity Capture-MS Homo sapiens
56 MYRIP  
Cross-Linking-MS (XL-MS) Homo sapiens
57 SPECC1L 23384
Affinity Capture-MS Homo sapiens
58 DDRGK1 65992
Cross-Linking-MS (XL-MS) Homo sapiens
59 BASP1 10409
Affinity Capture-MS Homo sapiens
60 EIF5B 9669
Cross-Linking-MS (XL-MS) Homo sapiens
61 PIK3C3 5289
Affinity Capture-MS Homo sapiens
62 TINF2  
Two-hybrid Homo sapiens
63 MYO1D 4642
Affinity Capture-MS Homo sapiens
64 Flot2 14252
Affinity Capture-MS Mus musculus
65 AKAP2 11217
Affinity Capture-MS Homo sapiens
66 CEP162  
Affinity Capture-MS Homo sapiens
67 RAB1A 5861
Affinity Capture-MS Homo sapiens
68 MYO1B 4430
Affinity Capture-MS Homo sapiens
69 CPLX1 10815
Cross-Linking-MS (XL-MS) Homo sapiens
70 LEO1 123169
Cross-Linking-MS (XL-MS) Homo sapiens
71 DAB2 1601
Affinity Capture-MS Homo sapiens
72 CD44 960
Affinity Capture-MS Homo sapiens
73 STAT5B 6777
Affinity Capture-MS Homo sapiens
74 GTSE1 51512
Affinity Capture-MS Homo sapiens
75 MECP2 4204
Affinity Capture-MS Homo sapiens
76 BTRC 8945
Two-hybrid Homo sapiens
77 USP7 7874
Affinity Capture-MS Homo sapiens
78 POTEKP 440915
Affinity Capture-MS Homo sapiens
79 SOX5 6660
Affinity Capture-MS Homo sapiens
80 ATP6AP1 537
Affinity Capture-MS Homo sapiens
81 Lima1  
Affinity Capture-MS Mus musculus
82 Tmed10 68581
Affinity Capture-MS Mus musculus
83 STAT1 6772
Proximity Label-MS Homo sapiens
84 MEST 4232
Two-hybrid Homo sapiens
85 TPT1 7178
Two-hybrid Homo sapiens
86 AP2B1 163
Affinity Capture-MS Homo sapiens
87 ACTG1 71
Affinity Capture-MS Homo sapiens
88 CHMP4C 92421
Affinity Capture-MS Homo sapiens
89 CPM 1368
Affinity Capture-MS Homo sapiens
90 NF2 4771
Affinity Capture-MS Homo sapiens
91 PPP1CA 5499
Affinity Capture-MS Homo sapiens
92 GATA4  
Affinity Capture-MS Homo sapiens
93 MYO18A 399687
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 COX15 1355
Affinity Capture-MS Homo sapiens
95 TLX3  
Affinity Capture-MS Homo sapiens
96 SORBS2  
Affinity Capture-MS Homo sapiens
97 LUZP1 7798
Affinity Capture-MS Homo sapiens
98 PALMD  
Affinity Capture-MS Homo sapiens
99 STOM 2040
Affinity Capture-MS Homo sapiens
100 COBL  
Affinity Capture-MS Homo sapiens
101 TMOD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 MAPRE1 22919
Affinity Capture-MS Homo sapiens
103 RNF38  
Affinity Capture-MS Homo sapiens
104 CLTCL1 8218
Affinity Capture-MS Homo sapiens
105 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
106 C10orf88  
Affinity Capture-MS Homo sapiens
107 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
108 CAMK2G 818
Affinity Capture-MS Homo sapiens
109 UBR5 51366
Affinity Capture-MS Homo sapiens
110 CDH1 999
Proximity Label-MS Homo sapiens
111 CHMP4B 128866
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 LRRFIP1 9208
Affinity Capture-MS Homo sapiens
113 BTF3 689
Affinity Capture-MS Homo sapiens
114 MYH9 4627
Affinity Capture-MS Homo sapiens
115 ACTN4 81
Affinity Capture-MS Homo sapiens
116 NTRK1 4914
Affinity Capture-MS Homo sapiens
117 TWF1 5756
Affinity Capture-MS Homo sapiens
118 ARHGAP11A  
Affinity Capture-MS Homo sapiens
119 TAB2  
Affinity Capture-MS Homo sapiens
120 CYBRD1 79901
Affinity Capture-MS Homo sapiens
121 MKRN2 23609
Affinity Capture-RNA Homo sapiens
122 FLNB 2317
Affinity Capture-MS Homo sapiens
123 BMP2K 55589
Affinity Capture-MS Homo sapiens
124 Calml3  
Affinity Capture-MS Mus musculus
125 ACTB 60
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 PPP1R18 170954
Affinity Capture-MS Homo sapiens
127 UBE2D3 7323
Two-hybrid Homo sapiens
128 Coro1c 23790
Affinity Capture-MS Mus musculus
129 MAGOH 4116
Affinity Capture-MS Homo sapiens
130 RPLP0 6175
Co-fractionation Homo sapiens
131 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
132 EPB41L5 57669
Affinity Capture-MS Homo sapiens
133 FLOT2 2319
Affinity Capture-MS Homo sapiens
134 PICALM 8301
Affinity Capture-MS Homo sapiens
135 ARPC1A 10552
Affinity Capture-MS Homo sapiens
136 DUSP23 54935
Two-hybrid Homo sapiens
137 DNM1L 10059
Affinity Capture-MS Homo sapiens
138 NFATC4 4776
Affinity Capture-MS Homo sapiens
139 LRCH3 84859
Affinity Capture-MS Homo sapiens
140 ACD  
Two-hybrid Homo sapiens
141 TPRN 286262
Affinity Capture-MS Homo sapiens
142 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 DST 667
Affinity Capture-MS Homo sapiens
144 LIMA1 51474
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 TLX2  
Affinity Capture-MS Homo sapiens
146 ACTN1 87
Affinity Capture-MS Homo sapiens
147 OGT 8473
Reconstituted Complex Homo sapiens
148 BRF1  
Affinity Capture-MS Homo sapiens
149 PPP1R9B 84687
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 EPS15 2060
Affinity Capture-MS Homo sapiens
151 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
152 CLINT1 9685
Affinity Capture-MS Homo sapiens
153 Myh9 17886
Affinity Capture-MS Mus musculus
154 NKX2-5  
Affinity Capture-MS Homo sapiens
155 GOLGA6D  
Cross-Linking-MS (XL-MS) Homo sapiens
156 SPECC1 92521
Affinity Capture-MS Homo sapiens
157 ESPN  
Cross-Linking-MS (XL-MS) Homo sapiens
158 LGALS1 3956
Affinity Capture-MS Homo sapiens
159 ILKAP 80895
Affinity Capture-MS Homo sapiens
160 ECT2 1894
Affinity Capture-MS Homo sapiens
161 NAP1L4 4676
Affinity Capture-MS Homo sapiens
162 SCN11A 11280
Cross-Linking-MS (XL-MS) Homo sapiens
163 ERBB2IP 55914
Affinity Capture-MS Homo sapiens
164 LMO7 4008
Affinity Capture-MS Homo sapiens
165 RLIM 51132
Affinity Capture-MS Homo sapiens
166 NUMB 8650
Affinity Capture-MS Homo sapiens
167 BRD2  
Affinity Capture-MS Homo sapiens
168 ARPC3 10094
Affinity Capture-MS Homo sapiens
169 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
170 SURF6  
Affinity Capture-MS Homo sapiens
171 FN1 2335
Affinity Capture-MS Homo sapiens
172 MYO1E 4643
Affinity Capture-MS Homo sapiens
173 PALM 5064
Affinity Capture-MS Homo sapiens
174 CTTN 2017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 MYO5C 55930
Affinity Capture-MS Homo sapiens
176 MYO5A 4644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 MYO19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 FBXO6 26270
Affinity Capture-MS Homo sapiens
179 CD59 966
Affinity Capture-MS Homo sapiens
180 DIXDC1  
Affinity Capture-MS Homo sapiens
181 HNRNPUL1 11100
Co-fractionation Homo sapiens
182 HOMER1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 CORO1C 23603
Affinity Capture-MS Homo sapiens
184 SUZ12  
Affinity Capture-MS Homo sapiens
185 ECE1 1889
Co-fractionation Homo sapiens
186 MYO1C 4641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 CDC42 998
Affinity Capture-MS Homo sapiens
188 RAI14 26064
Affinity Capture-MS Homo sapiens
189 AURKB 9212
Affinity Capture-MS Homo sapiens
190 CDK2 1017
Affinity Capture-MS Homo sapiens
191 MAPK6  
Two-hybrid Homo sapiens
192 TPM1 7168
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 HOMER2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 SYNPO 11346
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 GNAS 2778
Affinity Capture-MS Homo sapiens
196 FOS 2353
Proximity Label-MS Homo sapiens
197 Flnb 286940
Affinity Capture-MS Mus musculus
198 MYC  
Affinity Capture-MS Homo sapiens
199 RPA3 6119
Proximity Label-MS Homo sapiens
200 XPR1 9213
Affinity Capture-MS Homo sapiens
201 GNB2 2783
Affinity Capture-MS Homo sapiens
202 NAP1L1 4673
Affinity Capture-MS Homo sapiens
203 ATP6V1A 523
Affinity Capture-MS Homo sapiens
204 DLST 1743
Affinity Capture-MS Homo sapiens
205 TMOD3 29766
Affinity Capture-MS Homo sapiens
206 AP2A2 161
Affinity Capture-MS Homo sapiens
207 CFL1 1072
Affinity Capture-MS Homo sapiens
208 CFL2 1073
Affinity Capture-MS Homo sapiens
209 CGN  
Affinity Capture-MS Homo sapiens
210 MLPH  
Cross-Linking-MS (XL-MS) Homo sapiens
211 FLII 2314
Affinity Capture-MS Homo sapiens
212 PARP1 142
Proximity Label-MS Homo sapiens
213 BMI1  
Affinity Capture-MS Homo sapiens
214 TXNDC5 81567
Co-fractionation Homo sapiens
215 CLTC 1213
Affinity Capture-MS Homo sapiens
216 MPRIP 23164
Affinity Capture-MS Homo sapiens
217 PACSIN3 29763
Affinity Capture-MS Homo sapiens
218 FSCN1 6624
Affinity Capture-MS Homo sapiens
219 Ppp1cb 19046
Affinity Capture-MS Mus musculus
220 ARPC5L 81873
Affinity Capture-MS Homo sapiens
221 LIMCH1 22998
Cross-Linking-MS (XL-MS) Homo sapiens
222 TPM4 7171
Co-fractionation Homo sapiens
223 ARPC1B 10095
Affinity Capture-MS Homo sapiens
224 FAM133A 286499
Affinity Capture-MS Homo sapiens
225 ACTBL2 345651
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 SPTBN1 6711
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
228 GSN 2934
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
229 DUSP19  
Affinity Capture-MS Homo sapiens
230 BTK 695
Affinity Capture-MS Homo sapiens
231 SVIL 6840
Affinity Capture-MS Homo sapiens
232 NUDT21 11051
Two-hybrid Homo sapiens
233 FHL1 2273
Two-hybrid Homo sapiens
234 ARRB2 409
Affinity Capture-MS Homo sapiens
235 SPTAN1 6709
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
236 Tmod3 50875
Affinity Capture-MS Mus musculus
237 ITPKA  
Affinity Capture-MS Homo sapiens
238 KIF14 9928
Affinity Capture-MS Homo sapiens
239 ACTA2 59
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 NUP133 55746
Co-fractionation Homo sapiens
241 IARS 3376
Affinity Capture-MS Homo sapiens
242 JUP 3728
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
243 SSFA2 6744
Affinity Capture-MS Homo sapiens
244 TP53 7157
Affinity Capture-MS Homo sapiens
245 AP2M1 1173
Affinity Capture-MS Homo sapiens
246 ERLIN1 10613
Affinity Capture-MS Homo sapiens
247 SIPA1 6494
Affinity Capture-MS Homo sapiens
248 SNUPN 10073
Two-hybrid Homo sapiens
249 GOLGA6B  
Cross-Linking-MS (XL-MS) Homo sapiens
250 CALU 813
Co-fractionation Homo sapiens
251 MISP 126353
Affinity Capture-MS Homo sapiens
252 PRNP 5621
Affinity Capture-MS Homo sapiens
253 SSH2  
Affinity Capture-MS Homo sapiens
254 CDK2AP2  
Two-hybrid Homo sapiens
255 WDR1 9948
Affinity Capture-MS Homo sapiens
256 PDHA1 5160
Affinity Capture-MS Homo sapiens
257 NEXN 91624
Affinity Capture-MS Homo sapiens
258 CAPZA2 830
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
259 PRMT1 3276
Affinity Capture-MS Homo sapiens
260 PTPN2 5771
Affinity Capture-MS Homo sapiens
261 FCHO2 115548
Affinity Capture-MS Homo sapiens
262 DNMBP 23268
Affinity Capture-MS Homo sapiens
263 MTHFD1 4522
Co-fractionation Homo sapiens
264 Myh10 77579
Affinity Capture-MS Mus musculus
265 ESR1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
266 BAK1 578
Two-hybrid Homo sapiens
267 PPP1R9A  
Affinity Capture-MS Homo sapiens
268 Samm50  
Affinity Capture-MS Mus musculus
269 TERF1 7013
Two-hybrid Homo sapiens
270 MCM5 4174
Affinity Capture-MS Homo sapiens
271 TMOD2 29767
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 AFAP1 60312
Affinity Capture-MS Homo sapiens
273 MOV10 4343
Affinity Capture-RNA Homo sapiens
274 EZH2  
Affinity Capture-MS Homo sapiens
275 INF2 64423
Affinity Capture-MS Homo sapiens
276 LRRK2 120892
Affinity Capture-MS Homo sapiens
277 CORO2A  
Affinity Capture-MS Homo sapiens
278 ARPC4 10093
Affinity Capture-MS Homo sapiens
279 FLNA 2316
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
280 PINK1  
Affinity Capture-MS Homo sapiens
281 CLTA 1211
Affinity Capture-MS Homo sapiens
282 SDC4 6385
Affinity Capture-MS Homo sapiens
283 ZIC3  
Affinity Capture-MS Homo sapiens
284 FLOT1 10211
Affinity Capture-MS Homo sapiens
285 C14orf166 51637
Affinity Capture-MS Homo sapiens
286 Flot1 14251
Affinity Capture-MS Mus musculus
287 ERG  
Affinity Capture-MS Homo sapiens
288 EZR 7430
Proximity Label-MS Homo sapiens
289 MYO6 4646
Affinity Capture-MS Homo sapiens
290 UHRF1 29128
Affinity Capture-MS Homo sapiens
291 UBE2Q2 92912
Affinity Capture-MS Homo sapiens
292 CPLX2 10814
Cross-Linking-MS (XL-MS) Homo sapiens
293 ANXA2 302
Affinity Capture-MS Homo sapiens
294 PTRF 284119
Affinity Capture-MS Homo sapiens
295 Myo1c 17913
Affinity Capture-MS Mus musculus
296 Supt5  
Two-hybrid Mus musculus
297 CAV1 857
Affinity Capture-MS Homo sapiens
298 GPRC5A 9052
Affinity Capture-MS Homo sapiens
299 TIMM13 26517
Affinity Capture-MS Homo sapiens
300 DSG2 1829
Affinity Capture-MS Homo sapiens
301 DYRK1A 1859
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here