Gene description for AKAP2
Gene name A kinase (PRKA) anchor protein 2
Gene symbol AKAP2
Other names/aliases AKAP-2
AKAPKL
PRKA2
Species Homo sapiens
 Database cross references - AKAP2
ExoCarta ExoCarta_11217
Vesiclepedia VP_11217
Entrez Gene 11217
HGNC 372
MIM 604582
UniProt Q9Y2D5  
 AKAP2 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for AKAP2
 Experiment description of studies that identified AKAP2 in sEVs
1
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for AKAP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ANLN 54443
Affinity Capture-MS Homo sapiens
2 LIMA1 51474
Affinity Capture-MS Homo sapiens
3 LUZP4  
Affinity Capture-MS Homo sapiens
4 PPP1CB 5500
Affinity Capture-MS Homo sapiens
5 Myh9 17886
Affinity Capture-MS Mus musculus
6 WDR77 79084
Affinity Capture-MS Homo sapiens
7 Lima1  
Affinity Capture-MS Mus musculus
8 KIAA0196 9897
Co-fractionation Homo sapiens
9 KIF14 9928
Affinity Capture-MS Homo sapiens
10 ATG5 9474
Proximity Label-MS Homo sapiens
11 ECT2 1894
Affinity Capture-MS Homo sapiens
12 CHMP4C 92421
Affinity Capture-MS Homo sapiens
13 Calml3  
Affinity Capture-MS Mus musculus
14 PRKAR2A 5576
Protein-peptide Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
15 DBN1 1627
Affinity Capture-MS Homo sapiens
16 PDHA1 5160
Affinity Capture-MS Homo sapiens
17 CAPZA2 830
Affinity Capture-MS Homo sapiens
18 PDLIM7 9260
Affinity Capture-MS Homo sapiens
19 MYO5C 55930
Affinity Capture-MS Homo sapiens
20 Actb 11461
Affinity Capture-MS Mus musculus
21 CSTF2 1478
Co-fractionation Homo sapiens
22 BRE 9577
Co-fractionation Homo sapiens
23 PRKAR2B 5577
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 Myh10 77579
Affinity Capture-MS Mus musculus
25 BABAM1 29086
Co-fractionation Homo sapiens
26 PRKACA 5566
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 SYNPO 11346
Affinity Capture-MS Homo sapiens
28 CDH1 999
Proximity Label-MS Homo sapiens
29 Flnb 286940
Affinity Capture-MS Mus musculus
30 MYC  
Affinity Capture-MS Homo sapiens
31 MYH9 4627
Affinity Capture-MS Homo sapiens
32 Tmod3 50875
Affinity Capture-MS Mus musculus
33 FLNA 2316
Affinity Capture-MS Homo sapiens
34 PINK1  
Affinity Capture-MS Homo sapiens
35 CIT 11113
Affinity Capture-MS Homo sapiens
36 KIF5B 3799
Co-fractionation Homo sapiens
37 Flot1 14251
Affinity Capture-MS Mus musculus
38 SART3 9733
Co-fractionation Homo sapiens
39 PIH1D1  
Co-fractionation Homo sapiens
40 IQGAP1 8826
Affinity Capture-MS Homo sapiens
41 CHMP4B 128866
Affinity Capture-MS Homo sapiens
42 CALM3 808
Affinity Capture-MS Homo sapiens
43 Coro1c 23790
Affinity Capture-MS Mus musculus
44 Sept9  
Affinity Capture-MS Mus musculus
45 Flot2 14252
Affinity Capture-MS Mus musculus
46 Prkar2a 19087
Affinity Capture-MS Mus musculus
47 RPP38 10557
Co-fractionation Homo sapiens
48 STIP1 10963
Cross-Linking-MS (XL-MS) Homo sapiens
49 MYO18A 399687
Affinity Capture-MS Homo sapiens
50 CCDC8  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which AKAP2 is involved
No pathways found





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