Gene description for PRKACA
Gene name	protein kinase, cAMP-dependent, catalytic, alpha
Gene symbol	PRKACA
Other names/aliases	PKACA PPNAD4
Species	Homo sapiens
Database cross references - PRKACA
ExoCarta	ExoCarta_5566
Entrez Gene	5566
HGNC	9380
MIM	601639
UniProt	P17612
PRKACA identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for PRKACA

Molecular Function     ubiquitin protein ligase binding GO:0031625 IDA     cAMP-dependent protein kinase activity GO:0004691 NAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     protein kinase A regulatory subunit binding GO:0034237 IPI     protein kinase binding GO:0019901 IPI     protein serine/threonine/tyrosine kinase activity GO:0004712 IDA Biological Process     peptidyl-serine phosphorylation GO:0018105 IDA     calcium-mediated signaling using intracellular calcium source GO:0035584 TAS     regulation of bicellular tight junction assembly GO:2000810 IDA     cellular response to epinephrine stimulus GO:0071872 TAS     intracellular signal transduction GO:0035556 TAS     regulation of insulin secretion GO:0050796 TAS     regulation of proteasomal protein catabolic process GO:0061136 IDA     innate immune response GO:0045087 TAS     mesoderm formation GO:0001707 IEA     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     regulation of osteoblast differentiation GO:0045667 IDA     transmembrane transport GO:0055085 TAS     cell communication by electrical coupling involved in cardiac conduction GO:0086064 TAS     cellular response to glucagon stimulus GO:0071377 TAS     peptidyl-threonine phosphorylation GO:0018107 IEA     small molecule metabolic process GO:0044281 TAS     sperm capacitation GO:0048240 ISS     mitotic cell cycle GO:0000278 TAS     negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:1901621 IEA     signal transduction GO:0007165 TAS     regulation of cardiac muscle contraction GO:0055117 TAS     renal water homeostasis GO:0003091 TAS     protein phosphorylation GO:0006468 NAS     protein autophosphorylation GO:0046777 IEA     cellular response to parathyroid hormone stimulus GO:0071374 IEA     regulation of protein binding GO:0043393 TAS     regulation of protein processing GO:0070613 IEA     energy reserve metabolic process GO:0006112 TAS     neural tube closure GO:0001843 IEA     regulation of heart rate GO:0002027 TAS     activation of protein kinase A activity GO:0034199 TAS     positive regulation of protein export from nucleus GO:0046827 IEA     carbohydrate metabolic process GO:0005975 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 TAS     cytosolic calcium ion homeostasis GO:0051480 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     regulation of synaptic transmission GO:0050804 IEA     blood coagulation GO:0007596 TAS     activation of phospholipase C activity GO:0007202 TAS     cellular response to glucose stimulus GO:0071333 IDA     organelle organization GO:0006996 TAS     water transport GO:0006833 TAS     positive regulation of cell cycle arrest GO:0071158 ISS     triglyceride catabolic process GO:0019433 TAS     G2/M transition of mitotic cell cycle GO:0000086 TAS     gluconeogenesis GO:0006094 TAS     glucose metabolic process GO:0006006 TAS     regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 TAS Subcellular Localization     extracellular exosome GO:0070062 IDA     mitochondrion GO:0005739 IEA     AMP-activated protein kinase complex GO:0031588 IDA     cAMP-dependent protein kinase complex GO:0005952 NAS     nucleus GO:0005634 IDA     neuromuscular junction GO:0031594 IEA     calcium channel complex GO:0034704 TAS     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 TAS     centrosome GO:0005813 IDA     plasma membrane GO:0005886 IEA     motile cilium GO:0031514 IEA     membrane GO:0016020 IDA     sperm midpiece GO:0097225 IDA     ciliary base GO:0097546 TAS