Gene description for RANBP9
Gene name RAN binding protein 9
Gene symbol RANBP9
Other names/aliases BPM-L
BPM90
RANBPM
RanBP7
Species Homo sapiens
 Database cross references - RANBP9
ExoCarta ExoCarta_10048
Entrez Gene 10048
HGNC 13727
MIM 603854
UniProt Q96S59  
 RANBP9 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RANBP9
Molecular Function
    Ran GTPase binding GO:0008536 TAS
    enzyme binding GO:0019899 IPI
    protein binding GO:0005515 IPI
Biological Process
    microtubule nucleation GO:0007020 NAS
    negative regulation of ERK1 and ERK2 cascade GO:0070373 IMP
    axon guidance GO:0007411 TAS
    protein complex assembly GO:0006461 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
    microtubule associated complex GO:0005875 TAS
    nucleus GO:0005634 IDA
 Experiment description of studies that identified RANBP9 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RANBP9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MET 4233
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
2 HIPK2 28996
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
3 CALB1 793
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
4 DISC1 27185
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
5 UCHL1 7345
Two-hybrid Homo sapiens
6 AR 367
Invitro Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
7 RNPS1 10921
Affinity Capture-MS Homo sapiens
8 S100A7 6278
Invivo Homo sapiens
Two-hybrid Homo sapiens
9 USP11 8237
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
10 RAN 5901
Two-hybrid Homo sapiens
11 DYRK1B  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
12 NR3C1 2908
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
13 HSMPP8  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RANBP9 is involved
PathwayEvidenceSource
L1CAM interactions TAS Reactome





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