Experiment description of studies that identified C1qbp in exosomes

1 Experiment ID 1020 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Tsg101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Western blotting Immuno-EM PubMed ID 33827783     Organism Mus musculus Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name Panc02 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM

2 Experiment ID 1021 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Tsg101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Western blotting Immuno-EM PubMed ID 33827783     Organism Mus musculus Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name KPC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM

3 Experiment ID 1038 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name Panc02 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

4 Experiment ID 1039 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name Panc02 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

5 Experiment ID 1040 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name KPC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

6 Experiment ID 1041 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name KPC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

7 Experiment ID 1042 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name Panc02 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

8 Experiment ID 1043 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name Panc02 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

9 Experiment ID 1044 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name KPC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

10 Experiment ID 1045 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Homo sapiens Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic cancer cells Sample name KPC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

11 Experiment ID 1019 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Tsg101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Mus musculus Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic duct epithelial cells Sample name Primary pancreatic duct epithelial cells Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

12 Experiment ID 1046 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Mus musculus Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic duct epithelial cells Sample name Primary pancreatic duct epithelial cells Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

13 Experiment ID 1047 MISEV standards ✘ Biophysical techniques ✔ Tsg101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting PubMed ID 33827783     Organism Mus musculus Experiment description Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Authors Xie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF. Journal name Gut Publication year 2022 Sample Pancreatic duct epithelial cells Sample name Primary pancreatic duct epithelial cells Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting

Protein-protein interactions for C1qbp

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PHB 5245 Affinity Capture-MS Homo sapiens 2 Nphs2   Affinity Capture-MS Mus musculus 3 LBR 3930 Affinity Capture-MS Homo sapiens 4 YBX1 4904 Affinity Capture-MS Homo sapiens 5 Slc25a3 18674 Co-fractionation Mus musculus 6 CLCN7 1186 Affinity Capture-MS Homo sapiens 7 RNF220   Affinity Capture-MS Homo sapiens 8 MBD6   Affinity Capture-MS Homo sapiens 9 COX5B 1329 Affinity Capture-MS Homo sapiens 10 CLPX 10845 Affinity Capture-MS Homo sapiens 11 MRPL47 57129 Affinity Capture-MS Homo sapiens 12 NDUFS1 4719 Affinity Capture-MS Homo sapiens 13 ATP6V1B2 526 Affinity Capture-MS Homo sapiens 14 Hspb2 69253 Affinity Capture-MS Mus musculus 15 ERLIN1 10613 Affinity Capture-MS Homo sapiens 16 ZNF579   Affinity Capture-MS Homo sapiens 17 STOML2 30968 Affinity Capture-MS Homo sapiens 18 GOLIM4 27333 Affinity Capture-MS Homo sapiens 19 TRPM7 54822 Affinity Capture-MS Homo sapiens 20 DHX29 54505 Affinity Capture-MS Homo sapiens 21 BNC2   Affinity Capture-MS Homo sapiens 22 ATP5A1 498 Affinity Capture-MS Homo sapiens 23 PRKCZ 5590 Two-hybrid Homo sapiens 24 CMAS 55907 Affinity Capture-MS Homo sapiens 25 ETFB 2109 Affinity Capture-MS Homo sapiens 26 ERLIN2 11160 Affinity Capture-MS Homo sapiens 27 LSM14B 149986 Affinity Capture-MS Homo sapiens 28 TMEM43 79188 Affinity Capture-MS Homo sapiens 29 PARK2   Reconstituted Complex Homo sapiens 30 LUC7L 55692 Affinity Capture-MS Homo sapiens 31 PUF60 22827 Affinity Capture-MS Homo sapiens 32 STOM 2040 Affinity Capture-MS Homo sapiens 33 CHCHD3 54927 Affinity Capture-MS Homo sapiens 34 SLC12A2 6558 Affinity Capture-MS Homo sapiens 35 KLHL13 90293 Affinity Capture-MS Homo sapiens 36 Mettl21e   Affinity Capture-MS Mus musculus 37 VDAC2 7417 Affinity Capture-MS Homo sapiens 38 RANBP9 10048 Affinity Capture-MS Homo sapiens 39 PHB2 11331 Affinity Capture-MS Homo sapiens 40 ALDH18A1 5832 Affinity Capture-MS Homo sapiens 41 SOAT1 6646 Affinity Capture-MS Homo sapiens 42 KIDINS220 57498 Affinity Capture-MS Homo sapiens 43 NDUFA2 4695 Affinity Capture-MS Homo sapiens 44 CHMP4B 128866 Affinity Capture-MS Homo sapiens 45 SS18L2   Affinity Capture-MS Homo sapiens 46 BAG1 573 Affinity Capture-MS Homo sapiens 47 PRKCDBP 112464 Affinity Capture-MS Homo sapiens 48 YBX3 8531 Affinity Capture-MS Homo sapiens 49 PTRF 284119 Affinity Capture-MS Homo sapiens 50 NDUFA7 4701 Affinity Capture-MS Homo sapiens 51 C14orf169   Affinity Capture-MS Homo sapiens 52 CHCHD2   Affinity Capture-MS Homo sapiens 53 ZFP91 80829 Affinity Capture-MS Homo sapiens 54 POLDIP2 26073 Affinity Capture-MS Homo sapiens 55 Zbtb7b   Affinity Capture-MS Mus musculus 56 UQCRC1 7384 Affinity Capture-MS Homo sapiens 57 RBBP7 5931 Affinity Capture-MS Homo sapiens 58 ABCD3 5825 Affinity Capture-MS Homo sapiens 59 ATP6V0A1 535 Affinity Capture-MS Homo sapiens 60 C1qbp 12261 Cross-Linking-MS (XL-MS) Mus musculus Cross-Linking-MS (XL-MS) Mus musculus 61 CHMP2B 25978 Affinity Capture-MS Homo sapiens 62 CC2D1B 200014 Affinity Capture-MS Homo sapiens 63 FLOT2 2319 Affinity Capture-MS Homo sapiens 64 CAV1 857 Affinity Capture-MS Homo sapiens 65 ATP5O 539 Affinity Capture-MS Homo sapiens 66 FLOT1 10211 Affinity Capture-MS Homo sapiens 67 Fancd2   Affinity Capture-MS Mus musculus 68 CHMP1A 5119 Affinity Capture-MS Homo sapiens View the network

Pathways in which C1qbp is involved

No pathways found